XPOT_ORYSJ
ID XPOT_ORYSJ Reviewed; 980 AA.
AC Q8H3A7; A0A0P0X8S3; Q8GTZ0;
DT 22-FEB-2012, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 03-AUG-2022, entry version 107.
DE RecName: Full=Exportin-T;
DE AltName: Full=Exportin(tRNA);
DE AltName: Full=Protein PAUSED homolog;
DE AltName: Full=tRNA exportin;
GN OrderedLocusNames=Os07g0613300, LOC_Os07g42180;
GN ORFNames=OJ1003_H02.130, P0616D06.103;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [5]
RP FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, AND DISRUPTION
RP PHENOTYPE.
RC STRAIN=cv. Dongjin;
RX PubMed=18850055; DOI=10.1093/abbs/40.10.893;
RA Yao C., Ge L., Li W., Zhao B., Li C., Ruan K., Lin H., Jin Y.;
RT "Expression and characterization of rice putative PAUSED gene.";
RL Acta Biochim. Biophys. Sin. 40:893-900(2008).
CC -!- FUNCTION: Probable tRNA nucleus export receptor which regulates tRNA
CC processing and facilitates tRNA translocation across the nuclear pore
CC complex. Is required for correct leaf initiation at different
CC developmental stages and may play a role in floral patterning.
CC {ECO:0000269|PubMed:18850055}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:18850055}. Cytoplasm
CC {ECO:0000269|PubMed:18850055}. Note=Shuttles between the nucleus and
CC the cytoplasm. {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Expressed in roots, stems, leaves, flowers and
CC embryos. {ECO:0000269|PubMed:18850055}.
CC -!- DISRUPTION PHENOTYPE: Reduced size in non-mature plants, delayed
CC panicle heading, reduced seed number and low seed fertility.
CC {ECO:0000269|PubMed:18850055}.
CC -!- SIMILARITY: Belongs to the exportin family. {ECO:0000305}.
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DR EMBL; AP003700; BAC79501.1; -; Genomic_DNA.
DR EMBL; AP005198; BAC16491.1; -; Genomic_DNA.
DR EMBL; AP008213; BAF22169.1; -; Genomic_DNA.
DR EMBL; AP014963; BAT02623.1; -; Genomic_DNA.
DR EMBL; AK067398; BAG90402.1; -; mRNA.
DR RefSeq; XP_015647679.1; XM_015792193.1.
DR AlphaFoldDB; Q8H3A7; -.
DR SMR; Q8H3A7; -.
DR STRING; 4530.OS07T0613300-01; -.
DR PaxDb; Q8H3A7; -.
DR PRIDE; Q8H3A7; -.
DR EnsemblPlants; Os07t0613300-01; Os07t0613300-01; Os07g0613300.
DR EnsemblPlants; Os07t0613300-02; Os07t0613300-02; Os07g0613300.
DR GeneID; 4343885; -.
DR Gramene; Os07t0613300-01; Os07t0613300-01; Os07g0613300.
DR Gramene; Os07t0613300-02; Os07t0613300-02; Os07g0613300.
DR KEGG; osa:4343885; -.
DR eggNOG; KOG2021; Eukaryota.
DR HOGENOM; CLU_004414_1_1_1; -.
DR InParanoid; Q8H3A7; -.
DR OMA; RFSPLCW; -.
DR OrthoDB; 142520at2759; -.
DR Proteomes; UP000000763; Chromosome 7.
DR Proteomes; UP000059680; Chromosome 7.
DR ExpressionAtlas; Q8H3A7; baseline and differential.
DR Genevisible; Q8H3A7; OS.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0016363; C:nuclear matrix; IBA:GO_Central.
DR GO; GO:0005643; C:nuclear pore; IBA:GO_Central.
DR GO; GO:0005049; F:nuclear export signal receptor activity; IEA:EnsemblPlants.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0000049; F:tRNA binding; IBA:GO_Central.
DR GO; GO:0009908; P:flower development; IEA:EnsemblPlants.
DR GO; GO:0010014; P:meristem initiation; IEA:EnsemblPlants.
DR GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR GO; GO:0071528; P:tRNA re-export from nucleus; IBA:GO_Central.
DR Gene3D; 1.25.10.10; -; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR013598; Exportin-1/Importin-b-like.
DR InterPro; IPR045546; Exportin-T_C.
DR InterPro; IPR040017; XPOT.
DR PANTHER; PTHR15952; PTHR15952; 1.
DR Pfam; PF19282; Exportin-T; 1.
DR Pfam; PF08389; Xpo1; 1.
DR SUPFAM; SSF48371; SSF48371; 1.
PE 2: Evidence at transcript level;
KW Cytoplasm; Nucleus; Receptor; Reference proteome; RNA-binding; Transport;
KW tRNA processing; tRNA-binding.
FT CHAIN 1..980
FT /note="Exportin-T"
FT /id="PRO_0000415613"
SQ SEQUENCE 980 AA; 108381 MW; 376D95A28E9584F0 CRC64;
MDDLEQAILL ASDSPAAAAA SPAVRAEALA YCARARDETP PSSLLHLCLY GLASSPHAHV
HFWCLQTIHD ALLLRRRLAL PDDLALLRSS LLSLAVSSNA ASPPFLRNKL AQLLALLVRF
EYPHVYPSYF LDLIPPSPPL PGPTDMFARV LVSLDDDLLS QDYPRNAEEA SDAGRVKDAM
RAQCVPQIAR HWHEAAVSLR AADPAVAAVA LDAARRCISW IDVSLVANDV FVPLLFDIAL
SPGSVAPLAA AAVGCLSAVA AKRMDARAKV ALLRSLMSAQ KGFGSPDSGL KMAHLVTAYA
VEALECYRKL GSSDADGAAA LEMLEEVLPA VFAAAESGDD DEVDSGSVLE FLSGYVSTMK
APTEKQLGHL GQILEVVRMQ MSYDPVYRGH LDVLDKIGKE EEDLMAEQRK DLIALFRSIC
RVAPGATQLF IRGLLVTALS SAEVSVEDVE VALTLFYRLG EIVGEEEIRT GAGLIRELVP
MLLSARFSCH THRLVALVYL DTISRYIKFM QENDQYVPHL LTVFLDERGI HHQNAHVSCH
AGYLLMRAIR LLKAKLVPYL DTILQSLQDA LVQFTATDWA NKDIKFSSSE DGSQIFEAVG
LLIGIEEVSP DKQVQCLTAL LNPLCQQIES LVMDAKAQGL EESSPRAIGL QQIIVALTMI
SKGFNERLVM GSRPTLGVMF KKTLDVVLQV LISFPNVKPL RSKIISFLHR MVEILGISVL
PCIPIALRQL LVDNEAKDMS EFLYLINQII CKFKSSANAL LEDVFPAIAS HLSVILSHDA
FSNGFASNTE EMRELQELEK RFYAFLLHIA THDLSTVLLT PSCRHYLENI MQLLLITSCS
HKEISHRKTC VQTFVNLIKD WCSSSEIEDK LPGFRVFMIE KFATGCCLQS VLDKSFNFRD
GISIALFGEI MMAQKVMYER FGENFVVNFV TKLREAHCPP DLAEQYYQKL QGNDIKAFKS
FYESLVMKIR QQQNGSLVFR
