ID   XPOT_PHANO              Reviewed;        1036 AA.
AC   Q0V6W0;
DT   01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-SEP-2006, sequence version 1.
DT   25-MAY-2022, entry version 72.
DE   RecName: Full=Exportin-T;
DE   AltName: Full=Exportin(tRNA);
DE   AltName: Full=Karyopherin-beta;
DE   AltName: Full=tRNA exportin;
GN   Name=LOS1; ORFNames=SNOG_00254;
OS   Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume
OS   blotch fungus) (Parastagonospora nodorum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Pleosporomycetidae; Pleosporales; Pleosporineae; Phaeosphaeriaceae;
OC   Parastagonospora.
OX   NCBI_TaxID=321614;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SN15 / ATCC MYA-4574 / FGSC 10173;
RX   PubMed=18024570; DOI=10.1105/tpc.107.052829;
RA   Hane J.K., Lowe R.G.T., Solomon P.S., Tan K.-C., Schoch C.L.,
RA   Spatafora J.W., Crous P.W., Kodira C.D., Birren B.W., Galagan J.E.,
RA   Torriani S.F.F., McDonald B.A., Oliver R.P.;
RT   "Dothideomycete-plant interactions illuminated by genome sequencing and EST
RT   analysis of the wheat pathogen Stagonospora nodorum.";
RL   Plant Cell 19:3347-3368(2007).
CC   -!- FUNCTION: tRNA nucleus export receptor which facilitates tRNA
CC       translocation across the nuclear pore complex. Involved in pre-tRNA
CC       splicing, probably by affecting the interaction of pre-tRNA with
CC       splicing endonuclease (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}.
CC       Note=Shuttles between the nucleus and the cytoplasm. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the exportin family. {ECO:0000305}.
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DR   EMBL; CH445325; EAT91749.1; -; Genomic_DNA.
DR   RefSeq; XP_001790945.1; XM_001790893.1.
DR   AlphaFoldDB; Q0V6W0; -.
DR   SMR; Q0V6W0; -.
DR   STRING; 13684.SNOT_00254; -.
DR   EnsemblFungi; SNOT_00254; SNOT_00254; SNOG_00254.
DR   GeneID; 5967693; -.
DR   KEGG; pno:SNOG_00254; -.
DR   eggNOG; KOG2021; Eukaryota.
DR   HOGENOM; CLU_004414_0_1_1; -.
DR   InParanoid; Q0V6W0; -.
DR   OMA; RFSPLCW; -.
DR   OrthoDB; 142520at2759; -.
DR   Proteomes; UP000001055; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0016363; C:nuclear matrix; IBA:GO_Central.
DR   GO; GO:0005643; C:nuclear pore; IBA:GO_Central.
DR   GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR   GO; GO:0000049; F:tRNA binding; IBA:GO_Central.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0071528; P:tRNA re-export from nucleus; IBA:GO_Central.
DR   Gene3D; 1.25.10.10; -; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR013598; Exportin-1/Importin-b-like.
DR   InterPro; IPR045546; Exportin-T_C.
DR   InterPro; IPR040017; XPOT.
DR   PANTHER; PTHR15952; PTHR15952; 1.
DR   Pfam; PF19282; Exportin-T; 1.
DR   Pfam; PF08389; Xpo1; 1.
DR   SUPFAM; SSF48371; SSF48371; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Nucleus; Reference proteome; RNA-binding; Transport;
KW   tRNA processing; tRNA-binding.
FT   CHAIN           1..1036
FT                   /note="Exportin-T"
FT                   /id="PRO_0000343101"
SQ   SEQUENCE   1036 AA;  116132 MW;  8402532FCC6578DC CRC64;
     MEAQVENAIQ IAFDPTSSQQ LRGQAVEFLE RLRSEGSAWQ ASLALFTRDP RPSDIIRHTS
     LDLVNNAVQE HRLDEQSLAY IKDTLMSHVR QSYAPGSSTA DTSHIQNKLM QTMTYLFAAL
     YPTSWRSFFD DFRALAGDQA TIGNVNTATT FLYLRMLVQV HDEIADQLVA RSKEETDRNT
     HLKDLIRDND IQKIALSWQE ILAKWRETDL SLVEMCLRTI GRYVSWIRLE LVINQDMITT
     FLEMAGQQGI SDPESPAGKV RDAAIDTFSE IVGKKMEPSN KIELILFLNL PDVVGQLITS
     PALAEFNSPN YDNDLAETVA KLVNNIVFDV VKILENDNVD EQTRQRADDL IRIFTPYLLR
     FFADQYDEVC STVIPSLTDL LTFLRKLQKK QGTVPPQYAA VLPPVLDAII AKMKYDETAD
     WGEEGEQTDE AEFQDLRRRL HVLQQTITTI DESYYIETLS RLVNGTFSGL SQGDQSLNWR
     DLELALYEMY LFGELAIRNQ GLFAKREPSS VAAQHLVGMM NSMIDSGLAN YPHPAVQLQY
     MEICVRYYQF FEQNPHLIPK VLENFVQLTH SSHVKVRSRS WYLFQRLVKH LRAQLGNVSY
     DIIQAVADLL TIKAELPDTS EDEMSSDEED QSADALFNSQ LYLFEAVGCI ASSNTVSAEN
     KKLYAQTIMS PLFVDLEQTL PQARNGDDRA TLQIHHIIMA LGTLARGYSD WVPSNNSSAV
     PHSDVADEFV KASEAILVAL ESLNSSSSIR HAARFAFSRM IAVLGSRLLQ QLPSWIEGLL
     SLSSSMDEIS TFLKVLGQVV FTFKSEISNI LDTVMTPVLQ RIFSALATTP SGTDDEIQLA
     ELRREYLNFL IVVLNQGLGS VLVSNTNQSS FETIISSIEN FARDTHDAPT ARLAIFVLIR
     MINVWCGPDK VGPGANQTPT SPATTQAPLP GFENYVVERF SPLAWSIPAS PGFNSKDAQA
     KQVLVEAANL QTEIVKKVGE PYVERLKSDL SGNGVAADGV DQYVRTLAGA LEGTKKEKEW
     RNFFVQFVDR MLSGRG