ID   XPOT_USTMA              Reviewed;        1106 AA.
AC   Q4PC84; A0A0D1E1F7;
DT   01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-2008, sequence version 2.
DT   25-MAY-2022, entry version 82.
DE   RecName: Full=Exportin-T;
DE   AltName: Full=Exportin(tRNA);
DE   AltName: Full=Karyopherin-beta;
DE   AltName: Full=tRNA exportin;
GN   Name=LOS1; ORFNames=UMAG_11401;
OS   Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC   Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Ustilago.
OX   NCBI_TaxID=237631;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=521 / FGSC 9021;
RX   PubMed=17080091; DOI=10.1038/nature05248;
RA   Kaemper J., Kahmann R., Boelker M., Ma L.-J., Brefort T., Saville B.J.,
RA   Banuett F., Kronstad J.W., Gold S.E., Mueller O., Perlin M.H.,
RA   Woesten H.A.B., de Vries R., Ruiz-Herrera J., Reynaga-Pena C.G.,
RA   Snetselaar K., McCann M., Perez-Martin J., Feldbruegge M., Basse C.W.,
RA   Steinberg G., Ibeas J.I., Holloman W., Guzman P., Farman M.L.,
RA   Stajich J.E., Sentandreu R., Gonzalez-Prieto J.M., Kennell J.C., Molina L.,
RA   Schirawski J., Mendoza-Mendoza A., Greilinger D., Muench K., Roessel N.,
RA   Scherer M., Vranes M., Ladendorf O., Vincon V., Fuchs U., Sandrock B.,
RA   Meng S., Ho E.C.H., Cahill M.J., Boyce K.J., Klose J., Klosterman S.J.,
RA   Deelstra H.J., Ortiz-Castellanos L., Li W., Sanchez-Alonso P.,
RA   Schreier P.H., Haeuser-Hahn I., Vaupel M., Koopmann E., Friedrich G.,
RA   Voss H., Schlueter T., Margolis J., Platt D., Swimmer C., Gnirke A.,
RA   Chen F., Vysotskaia V., Mannhaupt G., Gueldener U., Muensterkoetter M.,
RA   Haase D., Oesterheld M., Mewes H.-W., Mauceli E.W., DeCaprio D., Wade C.M.,
RA   Butler J., Young S.K., Jaffe D.B., Calvo S.E., Nusbaum C., Galagan J.E.,
RA   Birren B.W.;
RT   "Insights from the genome of the biotrophic fungal plant pathogen Ustilago
RT   maydis.";
RL   Nature 444:97-101(2006).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=521 / FGSC 9021;
RA   Gueldener U., Muensterkoetter M., Walter M.C., Mannhaupt G., Kahmann R.;
RL   Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: tRNA nucleus export receptor which facilitates tRNA
CC       translocation across the nuclear pore complex. Involved in pre-tRNA
CC       splicing, probably by affecting the interaction of pre-tRNA with
CC       splicing endonuclease (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}.
CC       Note=Shuttles between the nucleus and the cytoplasm. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the exportin family. {ECO:0000305}.
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DR   EMBL; CM003144; KIS69756.1; -; Genomic_DNA.
DR   RefSeq; XP_011388857.1; XM_011390555.1.
DR   AlphaFoldDB; Q4PC84; -.
DR   SMR; Q4PC84; -.
DR   STRING; 5270.UM02279P0; -.
DR   EnsemblFungi; KIS69756; KIS69756; UMAG_11401.
DR   GeneID; 23567289; -.
DR   KEGG; uma:UMAG_11401; -.
DR   VEuPathDB; FungiDB:UMAG_11401; -.
DR   eggNOG; KOG2021; Eukaryota.
DR   InParanoid; Q4PC84; -.
DR   OrthoDB; 142520at2759; -.
DR   Proteomes; UP000000561; Chromosome 5.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0016363; C:nuclear matrix; IBA:GO_Central.
DR   GO; GO:0005643; C:nuclear pore; IBA:GO_Central.
DR   GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR   GO; GO:0000049; F:tRNA binding; IBA:GO_Central.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0071528; P:tRNA re-export from nucleus; IBA:GO_Central.
DR   Gene3D; 1.25.10.10; -; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR013598; Exportin-1/Importin-b-like.
DR   InterPro; IPR045546; Exportin-T_C.
DR   InterPro; IPR040017; XPOT.
DR   PANTHER; PTHR15952; PTHR15952; 1.
DR   Pfam; PF19282; Exportin-T; 2.
DR   Pfam; PF08389; Xpo1; 1.
DR   SUPFAM; SSF48371; SSF48371; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Nucleus; Reference proteome; RNA-binding; Transport;
KW   tRNA processing; tRNA-binding.
FT   CHAIN           1..1106
FT                   /note="Exportin-T"
FT                   /id="PRO_0000343107"
FT   REGION          336..357
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1106 AA;  121188 MW;  87C1A63B446F5220 CRC64;
     MEEQLIQAVE IASNPLANAG PDVTSQALQF LEHLKTITHE SWSVGWSVWS ARNPQDNGPK
     YSQNARMFGL MLVDDFLANR ISLSTDPAAA VATLQQSAVE YIQNEYVAGS GDASVAYIKN
     KFAQVLAVLL LQTYNLPPPY TLLPTLLSMI RAHPAASPSQ QSTLQLPINP LTTDLVLRVL
     HDLSVTLGSD VTLRAVRSKE RLQRDAVIRD EIRANHASNI ADSVWRIVEE GFNRVNQGEH
     ASNPNSASGV RSMNFTNAVD LTAAATKIVE DYVSWIDINL VVTNQTVPLL FNVLHHPIPK
     IRTAAADALH GIVSKGMKPA DKLSLAQALN LPQVITPLES RTRTGPSAQN GQSDTSDSNI
     EFREHLAHLT NGLVLEMCKI LEESAAEEST RAAAEDLLNS LLPLVLAFLS DEYDDASEQT
     FSGVNMILSI YKKARRRGAE LTGARAEFLS NLIGVALQKM RFDDEAEWPA GSFGAAEDDD
     DDDDEEDAKF LEMRRSLQTI VGAIAAIDDK LFSTSVAQLV LSTFASFETS SSDSDGQISW
     QQIELALYVI HFYGDVMTTA TAAPKVGLSP AMFVQSPEAG SKGRAPKLGN EALAGLPLSN
     LGEMVQKLVQ SNVSSFPHPA VQLQFFECLV RYSNFFAARS GCVLDALPAF LDWRGVHHEK
     LGVCKRVNYL LYRFVRDLRA VAAVPMDYVE RLLQGLQDLL VVRAELPQVD ADEDPLIKAT
     APAGYFDSQL YLFETSGILV SLLNNAPNDQ VVLLKAISEP LSEQMRQAVQ AFQRNPTDLT
     SVLQVHHLML ALSSLSKGFP DLSPTSTQPE PQWVGVFKSI TEQVLVSIGA MNSFSVVREA
     ARGAFARMVS TCGKAVLPYI PGLIDALLSE VTSAELVDFV NFLSLVVNKY KDDVRSIVDQ
     LLLILVERIF FFLNQGVTGT DDAVEKSELQ KAYMNLLSSM VQSGMESVFV SDKNVGQLET
     VLQSVVFYST NSDAACQRTA FSILHRLVAS WAGSSAVNGS TEATLPGFER FIYEHLVPLI
     FEAPAKDTFD FKDAQSQIVL TEISTLAKTI FQKRGDEMIQ FLLEVYLPGI NCPPQLAQDF
     TTNLTTLDSK AFKKYLDAFI TRSRGG