CAP9_ARATH
ID CAP9_ARATH Reviewed; 692 AA.
AC P94017; Q8L644; Q9LQU0;
DT 13-APR-2004, integrated into UniProtKB/Swiss-Prot.
DT 13-APR-2004, sequence version 2.
DT 03-AUG-2022, entry version 126.
DE RecName: Full=Putative clathrin assembly protein At1g14910;
GN OrderedLocusNames=At1g14910; ORFNames=F10B6.32;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA], AND TISSUE SPECIFICITY.
RC STRAIN=cv. Columbia, and cv. Landsberg erecta;
RX PubMed=10231030; DOI=10.1093/dnares/6.1.51;
RA Gupta R., Gray J.C.;
RT "Characterization of a single-copy Arabidopsis gene encoding a protein
RT showing limited similarity to the N-terminus of the mammalian clathrin-
RT assembly protein AP180.";
RL DNA Res. 6:51-55(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
CC -!- SUBCELLULAR LOCATION: Membrane, clathrin-coated pit {ECO:0000250}.
CC Golgi apparatus {ECO:0000250}. Cytoplasmic vesicle, clathrin-coated
CC vesicle {ECO:0000250}. Note=Colocalized with clathrin in the Golgi
CC area. {ECO:0000250}.
CC -!- TISSUE SPECIFICITY: Expressed in the whole plant.
CC {ECO:0000269|PubMed:10231030}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF79231.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=CAA71879.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; Y10863; CAA71817.1; -; mRNA.
DR EMBL; Y10864; CAA71818.1; -; mRNA.
DR EMBL; Y10986; CAA71879.1; ALT_SEQ; Genomic_DNA.
DR EMBL; Y10987; CAA71880.1; -; mRNA.
DR EMBL; AC006917; AAF79231.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE29241.1; -; Genomic_DNA.
DR EMBL; AY096496; AAM20134.1; -; mRNA.
DR PIR; G86282; G86282.
DR PIR; T52617; T52617.
DR PIR; T52618; T52618.
DR RefSeq; NP_172944.1; NM_101360.4.
DR AlphaFoldDB; P94017; -.
DR SMR; P94017; -.
DR STRING; 3702.AT1G14910.1; -.
DR PaxDb; P94017; -.
DR PRIDE; P94017; -.
DR ProteomicsDB; 239191; -.
DR EnsemblPlants; AT1G14910.1; AT1G14910.1; AT1G14910.
DR GeneID; 838056; -.
DR Gramene; AT1G14910.1; AT1G14910.1; AT1G14910.
DR KEGG; ath:AT1G14910; -.
DR Araport; AT1G14910; -.
DR TAIR; locus:2006727; AT1G14910.
DR eggNOG; KOG0251; Eukaryota.
DR HOGENOM; CLU_014098_2_0_1; -.
DR InParanoid; P94017; -.
DR OrthoDB; 553740at2759; -.
DR PhylomeDB; P94017; -.
DR PRO; PR:P94017; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; P94017; baseline and differential.
DR Genevisible; P94017; AT.
DR GO; GO:0005905; C:clathrin-coated pit; IBA:GO_Central.
DR GO; GO:0030136; C:clathrin-coated vesicle; IBA:GO_Central.
DR GO; GO:0005576; C:extracellular region; HDA:TAIR.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR GO; GO:0005545; F:1-phosphatidylinositol binding; IBA:GO_Central.
DR GO; GO:0030276; F:clathrin binding; IDA:TAIR.
DR GO; GO:0032050; F:clathrin heavy chain binding; IBA:GO_Central.
DR GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IBA:GO_Central.
DR GO; GO:0000149; F:SNARE binding; IPI:TAIR.
DR GO; GO:0048268; P:clathrin coat assembly; IEA:InterPro.
DR GO; GO:0072583; P:clathrin-dependent endocytosis; IDA:TAIR.
DR GO; GO:0006900; P:vesicle budding from membrane; IBA:GO_Central.
DR Gene3D; 1.20.58.150; -; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR InterPro; IPR011417; ANTH_dom.
DR InterPro; IPR014712; ANTH_dom_sf.
DR InterPro; IPR045192; AP180-like.
DR InterPro; IPR013809; ENTH.
DR InterPro; IPR008942; ENTH_VHS.
DR PANTHER; PTHR22951; PTHR22951; 1.
DR Pfam; PF07651; ANTH; 1.
DR SMART; SM00273; ENTH; 1.
DR SUPFAM; SSF48464; SSF48464; 1.
DR PROSITE; PS50942; ENTH; 1.
PE 2: Evidence at transcript level;
KW Coated pit; Cytoplasmic vesicle; Endocytosis; Golgi apparatus; Membrane;
KW Phosphoprotein; Reference proteome; Repeat.
FT CHAIN 1..692
FT /note="Putative clathrin assembly protein At1g14910"
FT /id="PRO_0000187075"
FT DOMAIN 24..161
FT /note="ENTH"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00243"
FT REPEAT 532..548
FT /note="1"
FT REPEAT 549..564
FT /note="2; truncated"
FT REPEAT 565..581
FT /note="3"
FT REPEAT 582..598
FT /note="4"
FT REPEAT 599..615
FT /note="5"
FT REPEAT 616..632
FT /note="6"
FT REPEAT 633..649
FT /note="7"
FT REPEAT 650..666
FT /note="8"
FT REGION 325..383
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 532..666
FT /note="8 X 17 AA approximate tandem repeats"
FT COMPBIAS 348..375
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 363
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q9LHS0"
SQ SEQUENCE 692 AA; 75516 MW; A87E28F9A1D54609 CRC64;
MGTLQSWRRA YGALKDTTKV GLVRVNSDYA ELDVAIVKAT NHVECPPKDR HLRKIFLATS
AIRPRADVAY CIHALSRRLH KTRNWTVALK ALLVIHRLLR DGDPTFREEL LNFSQKGRIM
QISNFKDDSS PVAWDCSGWV RTYALFLEER LECFRVLKYD IEAERLPKVS PGQEKGYSKT
RDLDGEKLLE QLPALQQLLH RLIGCKPEGA AKHNHIIQYA LSLVLKESFK VYCAINEGII
NLVEKFFEMP RHEAIKALEI YKRAGLQAGN LSAFYEVCKG LELARNFQFP VLREPPQSFL
TTMEEYMRDA PQMVDVTSGP LLLTYTPDDG LTSEDVGPSH EEHETSSPSD SAVVPSEETQ
LSSQSPPSVE TPQNFIDTDD LLGLHDDTPD PLAILDQNAL ALALVSNDVD SSPFSFGQAR
DLDPSGWELA LVTTPSNDIS AATERQLAGG LDTLTLNSLY DDGALRAAQQ PAYGVPASNP
FEVQDLFAFS DSVSPPSAVN NPFGLYEPTY HQQEQQPQLQ VAPSPANPFG DFGEFPIVPV
SEPQSTTSFG AFPVPVSEPS NTTGFGEIPV VPVTEPPNTT AFGEFPVVPV SEPQNITGFG
ALPVTPASEP SNTTGFGEFP VVSVSAPQNT TGFGALPVIP VSEPSKTTGL GEFPVVPVSE
PQNTTGFGEF PVNAGAHEQH NSNNPFGSTG FL
