ID   CAPC_STAAU              Reviewed;         255 AA.
AC   P39852;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   25-MAY-2022, entry version 56.
DE   RecName: Full=Putative tyrosine-protein phosphatase CapC;
DE            EC=3.1.3.48;
GN   Name=capC;
OS   Staphylococcus aureus.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=1280;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 49951 / M / NCTC 10649;
RX   PubMed=7961465; DOI=10.1128/jb.176.22.7005-7016.1994;
RA   Lin W.S., Cunneen T., Lee C.Y.;
RT   "Sequence analysis and molecular characterization of genes required for the
RT   biosynthesis of type 1 capsular polysaccharide in Staphylococcus aureus.";
RL   J. Bacteriol. 176:7005-7016(1994).
CC   -!- FUNCTION: Required for the biosynthesis of type 1 capsular
CC       polysaccharide.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] +
CC         phosphate; Xref=Rhea:RHEA:10684, Rhea:RHEA-COMP:10136, Rhea:RHEA-
CC         COMP:10137, ChEBI:CHEBI:15377, ChEBI:CHEBI:43474, ChEBI:CHEBI:46858,
CC         ChEBI:CHEBI:82620; EC=3.1.3.48;
CC   -!- PATHWAY: Capsule biogenesis; capsule polysaccharide biosynthesis.
CC   -!- SIMILARITY: Belongs to the metallo-dependent hydrolases superfamily.
CC       CpsB/CapC family. {ECO:0000305}.
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DR   EMBL; U10927; AAA64642.1; -; Genomic_DNA.
DR   AlphaFoldDB; P39852; -.
DR   SMR; P39852; -.
DR   UniPathway; UPA00934; -.
DR   GO; GO:0030145; F:manganese ion binding; IEA:InterPro.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0045227; P:capsule polysaccharide biosynthetic process; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR016667; Caps_polysacc_synth_CpsB/CapC.
DR   InterPro; IPR016195; Pol/histidinol_Pase-like.
DR   PANTHER; PTHR39181; PTHR39181; 1.
DR   Pfam; PF19567; CpsB_CapC; 1.
DR   PIRSF; PIRSF016557; Caps_synth_CpsB; 1.
DR   SUPFAM; SSF89550; SSF89550; 1.
PE   3: Inferred from homology;
KW   Capsule biogenesis/degradation; Exopolysaccharide synthesis; Hydrolase;
KW   Protein phosphatase.
FT   CHAIN           1..255
FT                   /note="Putative tyrosine-protein phosphatase CapC"
FT                   /id="PRO_0000057886"
SQ   SEQUENCE   255 AA;  29377 MW;  C9DFC47BE8AD599F CRC64;
     MVDIHNHILV DVDDGPKSIN EAIELLKQAQ SENVTDIVAT PHHLHKRYSN DIEKVKIKLN
     ELKNNSEIKK LGLNLYVGQE IRITDQIIEG IKNKEIEGIN ESRYLLIEFP SNEIPYYTNQ
     LFYELQTMGY IPIIAHPERN KAIVQNLDLL FELINGGALS QITASSLLGD FGNNIRKLSL
     KMIDSNLAHF IASDAHSITN RPFMLKQLFN DRKLKAYYEE LESYLKNGKL VLTNERISKQ
     IPTQDYKQKK WFGLL