ID   XYLF_HAEIN              Reviewed;         332 AA.
AC   P45047;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   03-AUG-2022, entry version 113.
DE   RecName: Full=D-xylose-binding periplasmic protein;
DE   Flags: Precursor;
GN   Name=xylF; OrderedLocusNames=HI_1111;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
CC   -!- FUNCTION: Involved in the high-affinity D-xylose membrane transport
CC       system. Binds with high affinity to xylose (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the bacterial solute-binding protein 2 family.
CC       {ECO:0000305}.
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DR   EMBL; L42023; AAC22765.1; -; Genomic_DNA.
DR   PIR; C64183; C64183.
DR   RefSeq; NP_439268.1; NC_000907.1.
DR   RefSeq; WP_005693436.1; NC_000907.1.
DR   AlphaFoldDB; P45047; -.
DR   SMR; P45047; -.
DR   STRING; 71421.HI_1111; -.
DR   EnsemblBacteria; AAC22765; AAC22765; HI_1111.
DR   KEGG; hin:HI_1111; -.
DR   PATRIC; fig|71421.8.peg.1160; -.
DR   eggNOG; COG4213; Bacteria.
DR   HOGENOM; CLU_037628_13_0_6; -.
DR   OMA; YTDGWLP; -.
DR   PhylomeDB; P45047; -.
DR   BioCyc; HINF71421:G1GJ1-1146-MON; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0030288; C:outer membrane-bounded periplasmic space; IBA:GO_Central.
DR   GO; GO:0030246; F:carbohydrate binding; IBA:GO_Central.
DR   GO; GO:0048029; F:monosaccharide binding; IEA:InterPro.
DR   GO; GO:0015753; P:D-xylose transmembrane transport; IEA:InterPro.
DR   InterPro; IPR028082; Peripla_BP_I.
DR   InterPro; IPR025997; SBP_2_dom.
DR   InterPro; IPR013456; XylF.
DR   Pfam; PF13407; Peripla_BP_4; 1.
DR   SUPFAM; SSF53822; SSF53822; 1.
DR   TIGRFAMs; TIGR02634; xylF; 1.
PE   3: Inferred from homology;
KW   Periplasm; Reference proteome; Signal; Sugar transport; Transport.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000250"
FT   CHAIN           24..332
FT                   /note="D-xylose-binding periplasmic protein"
FT                   /id="PRO_0000031739"
SQ   SEQUENCE   332 AA;  35901 MW;  D5241F25CC0C3D34 CRC64;
     MKIKSALLTL VGALTVFSSS AHSKDLKIGL SIDDLRLERW QKDRDIFVNK AESMGAKVFV
     QSANGDDSAQ ISQIENMINK NIDVLVIIPH NGEVLSNVIS EAKKEGIKVL AYDRLINNAD
     LDFYVSFDNE KVGELQAKSI VAVKPEGNYF LMGGSPVDNN AKLFRKGQMK VLDPLIASGK
     IKVVGDQWVD SWLAEKALQI MENALTANKN NVDAVVASND ATAGGAIQAL SAQGLSGKVA
     ISGQDADLAA IKRIVNGSQT MTVYKPITKL ADKAAEIAVE LGKNEKIEAN AELNNGLKNV
     PAYLLDPIAV DKRNINETVI KDGFHTKESI YH