ID   XYLF_SULAC              Reviewed;         402 AA.
AC   Q4J710;
DT   22-APR-2020, integrated into UniProtKB/Swiss-Prot.
DT   02-AUG-2005, sequence version 1.
DT   25-MAY-2022, entry version 64.
DE   RecName: Full=Xylose/arabinose-binding protein XylF {ECO:0000305};
DE   AltName: Full=D-xylose/L-arabinose substrate binding protein {ECO:0000303|PubMed:29150511};
DE            Short=SBP {ECO:0000303|PubMed:29150511};
GN   Name=xylF {ECO:0000303|PubMed:29150511};
GN   OrderedLocusNames=Saci_2122 {ECO:0000312|EMBL:AAY81415.1};
OS   Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC
OS   15157 / NCIMB 11770).
OC   Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC   Sulfolobus.
OX   NCBI_TaxID=330779;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770;
RX   PubMed=15995215; DOI=10.1128/jb.187.14.4992-4999.2005;
RA   Chen L., Bruegger K., Skovgaard M., Redder P., She Q., Torarinsson E.,
RA   Greve B., Awayez M., Zibat A., Klenk H.-P., Garrett R.A.;
RT   "The genome of Sulfolobus acidocaldarius, a model organism of the
RT   Crenarchaeota.";
RL   J. Bacteriol. 187:4992-4999(2005).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY, FUNCTION, SUBUNIT, INDUCTION, AND
RP   DISRUPTION PHENOTYPE.
RC   STRAIN=MW001;
RX   PubMed=29150511; DOI=10.1128/aem.01273-17;
RA   Wagner M., Shen L., Albersmeier A., van der Kolk N., Kim S., Cha J.,
RA   Braesen C., Kalinowski J., Siebers B., Albers S.V.;
RT   "Sulfolobus acidocaldarius transports pentoses via a carbohydrate uptake
RT   transporter 2 (CUT2)-type ABC transporter and metabolizes them through the
RT   aldolase-independent Weimberg pathway.";
RL   Appl. Environ. Microbiol. 84:0-0(2018).
CC   -!- FUNCTION: Part of the ABC transporter complex XylFGH involved in the
CC       uptake of xylose and arabinose. {ECO:0000269|PubMed:29150511}.
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins (XylG),
CC       two transmembrane proteins (XylH) and a solute-binding protein (XylF).
CC       {ECO:0000305|PubMed:29150511}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000255}.
CC   -!- INDUCTION: Up-regulated in the presence of D-xylose, L-arabinose and D-
CC       arabinose. {ECO:0000269|PubMed:29150511}.
CC   -!- DISRUPTION PHENOTYPE: Deletion of the gene results in a growth defect
CC       on D-xylose and L-arabinose. {ECO:0000269|PubMed:29150511}.
CC   -!- SIMILARITY: Belongs to the bacterial solute-binding protein 2 family.
CC       {ECO:0000305}.
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DR   EMBL; CP000077; AAY81415.1; -; Genomic_DNA.
DR   RefSeq; WP_011278917.1; NC_007181.1.
DR   AlphaFoldDB; Q4J710; -.
DR   SMR; Q4J710; -.
DR   STRING; 330779.Saci_2122; -.
DR   EnsemblBacteria; AAY81415; AAY81415; Saci_2122.
DR   GeneID; 3472851; -.
DR   KEGG; sai:Saci_2122; -.
DR   PATRIC; fig|330779.12.peg.2127; -.
DR   eggNOG; arCOG07728; Archaea.
DR   HOGENOM; CLU_037628_3_5_2; -.
DR   OMA; DNIELRY; -.
DR   BRENDA; 7.5.2.13; 6160.
DR   Proteomes; UP000001018; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR   InterPro; IPR028082; Peripla_BP_I.
DR   InterPro; IPR025997; SBP_2_dom.
DR   Pfam; PF13407; Peripla_BP_4; 1.
DR   SUPFAM; SSF53822; SSF53822; 1.
PE   1: Evidence at protein level;
KW   Cell membrane; Membrane; Reference proteome; Sugar transport;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..402
FT                   /note="Xylose/arabinose-binding protein XylF"
FT                   /id="PRO_0000449396"
FT   TRANSMEM        38..58
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   402 AA;  42695 MW;  5A5C058F283FA0BD CRC64;
     MAKSKDEIKE EIAKAIINQV SKTDLSRRRA LSTLAKGGII AGVLAAFGAG FGSGYVTAPK
     GSSSSGVAPP QPGFMYGQVP EHPTWKIVFI NHVTTNPFFV PTQYGIQDAC LLLDCNYQWT
     GSETSDTTTM VNDMEAAISQ GANGIAVSVI SPNAFDKPTQ DALNAGIPVF AYNAYIPTDD
     PSYSQYHNPP YLGYIGQSLY ASGQLFGQRI LNLVPSGSRV ALFIATPGTA NIQPRIDGIQ
     SVIEGHYTID VVATGALVSD EQSAIESYFN SHPDVKGMFA VDAGSTQGVG NVLREHGIKT
     VSNGGTIAAG GYDLLPATIQ NIVDGYLDFT IDQQPYLQGF LPTLAIYLYL ISDTLVYPLN
     IDTGSKFITN SNIQPYLLAS RYEGSSTAYK PTSTTSSSSS SG