ID   XYLG_ECOL5              Reviewed;         513 AA.
AC   Q0TBN5;
DT   09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   09-JAN-2007, sequence version 2.
DT   03-AUG-2022, entry version 100.
DE   RecName: Full=Xylose import ATP-binding protein XylG {ECO:0000255|HAMAP-Rule:MF_01722};
DE            EC=7.5.2.10 {ECO:0000255|HAMAP-Rule:MF_01722};
GN   Name=xylG {ECO:0000255|HAMAP-Rule:MF_01722}; OrderedLocusNames=ECP_3670;
OS   Escherichia coli O6:K15:H31 (strain 536 / UPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=362663;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=536 / UPEC;
RX   PubMed=16879640; DOI=10.1111/j.1365-2958.2006.05255.x;
RA   Hochhut B., Wilde C., Balling G., Middendorf B., Dobrindt U.,
RA   Brzuszkiewicz E., Gottschalk G., Carniel E., Hacker J.;
RT   "Role of pathogenicity island-associated integrases in the genome
RT   plasticity of uropathogenic Escherichia coli strain 536.";
RL   Mol. Microbiol. 61:584-595(2006).
CC   -!- FUNCTION: Part of the ABC transporter complex XylFGH involved in xylose
CC       import. Responsible for energy coupling to the transport system.
CC       {ECO:0000255|HAMAP-Rule:MF_01722}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + D-xylose(out) + H2O = ADP + D-xylose(in) + H(+) +
CC         phosphate; Xref=Rhea:RHEA:29899, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474,
CC         ChEBI:CHEBI:53455, ChEBI:CHEBI:456216; EC=7.5.2.10;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01722};
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins (XylG),
CC       two transmembrane proteins (XylH) and a solute-binding protein (XylF).
CC       {ECO:0000255|HAMAP-Rule:MF_01722}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01722}; Peripheral membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01722}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. Xylose importer
CC       (TC 3.A.1.2.4) family. {ECO:0000255|HAMAP-Rule:MF_01722}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ABG71644.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; CP000247; ABG71644.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_001146503.1; NC_008253.1.
DR   AlphaFoldDB; Q0TBN5; -.
DR   SMR; Q0TBN5; -.
DR   STRING; 362663.ECP_3670; -.
DR   EnsemblBacteria; ABG71644; ABG71644; ECP_3670.
DR   KEGG; ecp:ECP_3670; -.
DR   HOGENOM; CLU_000604_92_3_6; -.
DR   OMA; VGREMSH; -.
DR   Proteomes; UP000009182; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015614; F:ABC-type D-xylose transporter activity; IEA:UniProtKB-EC.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 2.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR013455; ABC_transptr_xylose_ATP-bd.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00005; ABC_tran; 2.
DR   SMART; SM00382; AAA; 2.
DR   SUPFAM; SSF52540; SSF52540; 2.
DR   TIGRFAMs; TIGR02633; xylG; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
DR   PROSITE; PS51280; XYLG; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cell inner membrane; Cell membrane; Membrane;
KW   Nucleotide-binding; Repeat; Sugar transport; Translocase; Transport.
FT   CHAIN           1..513
FT                   /note="Xylose import ATP-binding protein XylG"
FT                   /id="PRO_0000271504"
FT   DOMAIN          5..242
FT                   /note="ABC transporter 1"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01722"
FT   DOMAIN          259..505
FT                   /note="ABC transporter 2"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01722"
FT   BINDING         37..44
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01722"
SQ   SEQUENCE   513 AA;  56484 MW;  4ACA069E470F6E42 CRC64;
     MPYLLEMKNI TKTFGSVKAI DNVSLRLNAG EIVSLCGENG SGKSTLMKVL CGIYPHGSYE
     GEIIFAGEEI QASHIRDTER KGIAIIHQEL ALVKELTVLE NIFLGNEITH NGIMDYDLMT
     LRCQKLLAQV SLSISPDTRV GDLGLGQQQL VEIAKALNKQ VRLLILDEPT ASLTEQETSV
     LLDIIRDLQQ HGIACIYISH KLNEVKAISD TICVIRDGQH IGTRDAAGMS EDDIITMMVG
     RELTALYPNE PHTTGDEILR IEHLTAWHPV NRHIKRVNDV SFSLKRGEIL GIAGLVGAGR
     TETIQCLFGV WPGQWEGKIY IDGKQVDIRN CQQAIAQGIA MVPEDRKRDG IVPVMAVGKN
     ITLAALKKFT GSISQLDDAA EQKCILESIQ QLKVKTSSPD LAIGRLSGGN QQKAILARCL
     LLNPRILILD EPTRGIDIGA KYEIYKLINQ LVQQGIAVIV ISSELPEVLG LSDRVLVMHE
     GKLKANLINH NLTQEQVMEA ALRSEHHVEK QSV