XYLG_ECOLI
ID XYLG_ECOLI Reviewed; 513 AA.
AC P37388; Q2M7N0;
DT 01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1994, sequence version 1.
DT 03-AUG-2022, entry version 165.
DE RecName: Full=Xylose import ATP-binding protein XylG {ECO:0000255|HAMAP-Rule:MF_01722};
DE EC=7.5.2.10 {ECO:0000255|HAMAP-Rule:MF_01722};
GN Name=xylG {ECO:0000255|HAMAP-Rule:MF_01722};
GN OrderedLocusNames=b3567, JW3539;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=8041620; DOI=10.1093/nar/22.13.2576;
RA Sofia H.J., Burland V., Daniels D.L., Plunkett G. III, Blattner F.R.;
RT "Analysis of the Escherichia coli genome. V. DNA sequence of the region
RT from 76.0 to 81.5 minutes.";
RL Nucleic Acids Res. 22:2576-2586(1994).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [4]
RP FUNCTION IN XYLOSE TRANSPORT, AND ABILITY TO TRANSPORT RIBOSE.
RC STRAIN=K12;
RX PubMed=9673030; DOI=10.1111/j.1574-6968.1998.tb13054.x;
RA Song S., Park C.;
RT "Utilization of D-ribose through D-xylose transporter.";
RL FEMS Microbiol. Lett. 163:255-261(1998).
CC -!- FUNCTION: Part of the ABC transporter complex XylFGH involved in xylose
CC import. Responsible for energy coupling to the transport system
CC (Probable). The XylFGH system can also transport ribose in absence of
CC xylose. {ECO:0000255|HAMAP-Rule:MF_01722, ECO:0000269|PubMed:9673030,
CC ECO:0000305}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + D-xylose(out) + H2O = ADP + D-xylose(in) + H(+) +
CC phosphate; Xref=Rhea:RHEA:29899, ChEBI:CHEBI:15377,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474,
CC ChEBI:CHEBI:53455, ChEBI:CHEBI:456216; EC=7.5.2.10;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_01722};
CC -!- SUBUNIT: The complex is composed of two ATP-binding proteins (XylG),
CC two transmembrane proteins (XylH) and a solute-binding protein (XylF).
CC {ECO:0000255|HAMAP-Rule:MF_01722}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_01722}; Peripheral membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_01722}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. Xylose importer
CC (TC 3.A.1.2.4) family. {ECO:0000255|HAMAP-Rule:MF_01722}.
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DR EMBL; U00039; AAB18544.1; -; Genomic_DNA.
DR EMBL; U00096; AAC76591.1; -; Genomic_DNA.
DR EMBL; AP009048; BAE77726.1; -; Genomic_DNA.
DR PIR; S47788; S47788.
DR RefSeq; NP_418024.1; NC_000913.3.
DR RefSeq; WP_001146473.1; NZ_LN832404.1.
DR AlphaFoldDB; P37388; -.
DR SMR; P37388; -.
DR BioGRID; 4262542; 7.
DR BioGRID; 852434; 1.
DR ComplexPortal; CPX-4388; Xylose ABC transporter complex.
DR IntAct; P37388; 7.
DR STRING; 511145.b3567; -.
DR TCDB; 3.A.1.2.4; the atp-binding cassette (abc) superfamily.
DR PaxDb; P37388; -.
DR PRIDE; P37388; -.
DR EnsemblBacteria; AAC76591; AAC76591; b3567.
DR EnsemblBacteria; BAE77726; BAE77726; BAE77726.
DR GeneID; 948127; -.
DR KEGG; ecj:JW3539; -.
DR KEGG; eco:b3567; -.
DR PATRIC; fig|1411691.4.peg.3145; -.
DR EchoBASE; EB2184; -.
DR eggNOG; COG1129; Bacteria.
DR HOGENOM; CLU_000604_92_3_6; -.
DR InParanoid; P37388; -.
DR OMA; VGREMSH; -.
DR PhylomeDB; P37388; -.
DR BioCyc; EcoCyc:XYLG-MON; -.
DR BioCyc; MetaCyc:XYLG-MON; -.
DR PRO; PR:P37388; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0055052; C:ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing; IC:ComplexPortal.
DR GO; GO:0016020; C:membrane; IC:ComplexPortal.
DR GO; GO:0015614; F:ABC-type D-xylose transporter activity; IEA:UniProtKB-EC.
DR GO; GO:0005524; F:ATP binding; ISM:EcoCyc.
DR GO; GO:0015148; F:D-xylose transmembrane transporter activity; IMP:EcoCyc.
DR GO; GO:0042732; P:D-xylose metabolic process; IMP:EcoCyc.
DR GO; GO:0015753; P:D-xylose transmembrane transport; IMP:EcoCyc.
DR Gene3D; 3.40.50.300; -; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR013455; ABC_transptr_xylose_ATP-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; SSF52540; 2.
DR TIGRFAMs; TIGR02633; xylG; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
DR PROSITE; PS51280; XYLG; 1.
PE 1: Evidence at protein level;
KW ATP-binding; Cell inner membrane; Cell membrane; Membrane;
KW Nucleotide-binding; Reference proteome; Repeat; Sugar transport;
KW Translocase; Transport.
FT CHAIN 1..513
FT /note="Xylose import ATP-binding protein XylG"
FT /id="PRO_0000093124"
FT DOMAIN 5..242
FT /note="ABC transporter 1"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01722"
FT DOMAIN 259..505
FT /note="ABC transporter 2"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01722"
FT BINDING 37..44
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01722"
SQ SEQUENCE 513 AA; 56470 MW; FAD2C65D178D50DF CRC64;
MPYLLEMKNI TKTFGSVKAI DNVCLRLNAG EIVSLCGENG SGKSTLMKVL CGIYPHGSYE
GEIIFAGEEI QASHIRDTER KGIAIIHQEL ALVKELTVLE NIFLGNEITH NGIMDYDLMT
LRCQKLLAQV SLSISPDTRV GDLGLGQQQL VEIAKALNKQ VRLLILDEPT ASLTEQETSI
LLDIIRDLQQ HGIACIYISH KLNEVKAISD TICVIRDGQH IGTRDAAGMS EDDIITMMVG
RELTALYPNE PHTTGDEILR IEHLTAWHPV NRHIKRVNDV SFSLKRGEIL GIAGLVGAGR
TETIQCLFGV WPGQWEGKIY IDGKQVDIRN CQQAIAQGIA MVPEDRKRDG IVPVMAVGKN
ITLAALNKFT GGISQLDDAA EQKCILESIQ QLKVKTSSPD LAIGRLSGGN QQKAILARCL
LLNPRILILD EPTRGIDIGA KYEIYKLINQ LVQQGIAVIV ISSELPEVLG LSDRVLVMHE
GKLKANLINH NLTQEQVMEA ALRSEHHVEK QSV
