ID   XYLG_ECOUT              Reviewed;         513 AA.
AC   Q1R528;
DT   09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   09-JAN-2007, sequence version 2.
DT   03-AUG-2022, entry version 101.
DE   RecName: Full=Xylose import ATP-binding protein XylG {ECO:0000255|HAMAP-Rule:MF_01722};
DE            EC=7.5.2.10 {ECO:0000255|HAMAP-Rule:MF_01722};
GN   Name=xylG {ECO:0000255|HAMAP-Rule:MF_01722}; OrderedLocusNames=UTI89_C4108;
OS   Escherichia coli (strain UTI89 / UPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=364106;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UTI89 / UPEC;
RX   PubMed=16585510; DOI=10.1073/pnas.0600938103;
RA   Chen S.L., Hung C.-S., Xu J., Reigstad C.S., Magrini V., Sabo A.,
RA   Blasiar D., Bieri T., Meyer R.R., Ozersky P., Armstrong J.R., Fulton R.S.,
RA   Latreille J.P., Spieth J., Hooton T.M., Mardis E.R., Hultgren S.J.,
RA   Gordon J.I.;
RT   "Identification of genes subject to positive selection in uropathogenic
RT   strains of Escherichia coli: a comparative genomics approach.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:5977-5982(2006).
CC   -!- FUNCTION: Part of the ABC transporter complex XylFGH involved in xylose
CC       import. Responsible for energy coupling to the transport system.
CC       {ECO:0000255|HAMAP-Rule:MF_01722}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + D-xylose(out) + H2O = ADP + D-xylose(in) + H(+) +
CC         phosphate; Xref=Rhea:RHEA:29899, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474,
CC         ChEBI:CHEBI:53455, ChEBI:CHEBI:456216; EC=7.5.2.10;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01722};
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins (XylG),
CC       two transmembrane proteins (XylH) and a solute-binding protein (XylF).
CC       {ECO:0000255|HAMAP-Rule:MF_01722}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01722}; Peripheral membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01722}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. Xylose importer
CC       (TC 3.A.1.2.4) family. {ECO:0000255|HAMAP-Rule:MF_01722}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ABE09536.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; CP000243; ABE09536.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_001146512.1; NC_007946.1.
DR   AlphaFoldDB; Q1R528; -.
DR   SMR; Q1R528; -.
DR   EnsemblBacteria; ABE09536; ABE09536; UTI89_C4108.
DR   KEGG; eci:UTI89_C4108; -.
DR   HOGENOM; CLU_000604_92_3_6; -.
DR   OMA; VGREMSH; -.
DR   Proteomes; UP000001952; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015614; F:ABC-type D-xylose transporter activity; IEA:UniProtKB-EC.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 2.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR013455; ABC_transptr_xylose_ATP-bd.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00005; ABC_tran; 2.
DR   SMART; SM00382; AAA; 2.
DR   SUPFAM; SSF52540; SSF52540; 2.
DR   TIGRFAMs; TIGR02633; xylG; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
DR   PROSITE; PS51280; XYLG; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cell inner membrane; Cell membrane; Membrane;
KW   Nucleotide-binding; Repeat; Sugar transport; Translocase; Transport.
FT   CHAIN           1..513
FT                   /note="Xylose import ATP-binding protein XylG"
FT                   /id="PRO_0000271501"
FT   DOMAIN          5..242
FT                   /note="ABC transporter 1"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01722"
FT   DOMAIN          259..505
FT                   /note="ABC transporter 2"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01722"
FT   BINDING         37..44
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01722"
SQ   SEQUENCE   513 AA;  56430 MW;  865A512B58A92D25 CRC64;
     MPYLLEMKNI TKTFGSVKAI DNVSLRLNAG EIVSLCGENG SGKSTLMKVL CGIYPHGSYE
     GEIIFAGEEI QASHIRDTER KGIAIIHQEL ALVKELTVLE NIFLGNEITH NGIMDYDLMT
     LRCQKLLAQV SLSISPDTRV GDLGLGQQQL VEIAKALNKQ VRLLILDEPT ASLTEQETSV
     LLDIIRDLQQ HGIACIYISH KLNEVKAISD TICVIRDGQH IGTRDAAGMS EDDIITMMVG
     RELTALYPNE PHTTGDEILR IEHLTAWHPV NRHIKRVNDV SFSLKRGEIL GIAGLVGAGR
     TETIQCLFGV WPGQWEGKIY IDGKQVDIRN CQQAIAQGIA MVPEDRKRDG IVPVMAVGKN
     ITLAALNKFT GGISQLDDAA EQKCILESIQ QLKVKTSSSD LAIGRLSGGN QQKAILARCL
     LLNPRILILD EPTRGIDIGA KYEIYKLINQ LVQQGIAVIV ISSELPEVLG LSDRVLVMHE
     GKLKANLINH NLTQEQVMEA ALRSEHHVEK QSV