ID   XYLG_HAEIN              Reviewed;         503 AA.
AC   P45046;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   03-AUG-2022, entry version 134.
DE   RecName: Full=Xylose import ATP-binding protein XylG {ECO:0000255|HAMAP-Rule:MF_01722};
DE            EC=7.5.2.10 {ECO:0000255|HAMAP-Rule:MF_01722};
GN   Name=xylG {ECO:0000255|HAMAP-Rule:MF_01722}; OrderedLocusNames=HI_1110;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
CC   -!- FUNCTION: Part of the ABC transporter complex XylFGH involved in xylose
CC       import. Responsible for energy coupling to the transport system.
CC       {ECO:0000255|HAMAP-Rule:MF_01722}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + D-xylose(out) + H2O = ADP + D-xylose(in) + H(+) +
CC         phosphate; Xref=Rhea:RHEA:29899, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474,
CC         ChEBI:CHEBI:53455, ChEBI:CHEBI:456216; EC=7.5.2.10;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01722};
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins (XylG),
CC       two transmembrane proteins (XylH) and a solute-binding protein (XylF).
CC       {ECO:0000255|HAMAP-Rule:MF_01722}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01722}; Peripheral membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01722}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. Xylose importer
CC       (TC 3.A.1.2.4) family. {ECO:0000255|HAMAP-Rule:MF_01722}.
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DR   EMBL; L42023; AAC22764.1; -; Genomic_DNA.
DR   PIR; B64183; B64183.
DR   RefSeq; NP_439267.1; NC_000907.1.
DR   RefSeq; WP_005693435.1; NC_000907.1.
DR   AlphaFoldDB; P45046; -.
DR   SMR; P45046; -.
DR   STRING; 71421.HI_1110; -.
DR   EnsemblBacteria; AAC22764; AAC22764; HI_1110.
DR   KEGG; hin:HI_1110; -.
DR   PATRIC; fig|71421.8.peg.1159; -.
DR   eggNOG; COG1129; Bacteria.
DR   HOGENOM; CLU_000604_92_3_6; -.
DR   OMA; VGREMSH; -.
DR   PhylomeDB; P45046; -.
DR   BioCyc; HINF71421:G1GJ1-1145-MON; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015614; F:ABC-type D-xylose transporter activity; IEA:UniProtKB-EC.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 2.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR013455; ABC_transptr_xylose_ATP-bd.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00005; ABC_tran; 2.
DR   SMART; SM00382; AAA; 2.
DR   SUPFAM; SSF52540; SSF52540; 2.
DR   TIGRFAMs; TIGR02633; xylG; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
DR   PROSITE; PS51280; XYLG; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cell inner membrane; Cell membrane; Membrane;
KW   Nucleotide-binding; Reference proteome; Repeat; Sugar transport;
KW   Translocase; Transport.
FT   CHAIN           1..503
FT                   /note="Xylose import ATP-binding protein XylG"
FT                   /id="PRO_0000093125"
FT   DOMAIN          4..241
FT                   /note="ABC transporter 1"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01722"
FT   DOMAIN          258..499
FT                   /note="ABC transporter 2"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01722"
FT   BINDING         36..43
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01722"
SQ   SEQUENCE   503 AA;  55680 MW;  B8D2FB066B83022C CRC64;
     MALLEMKHIT KKFGDVTALH NISIELEAGE ILSLCGENGS GKSTLMKILC GIYPCGDYSG
     DIYFSESELK ARNIRDTEEK GISIIHQELT LVKNMSVLEN IFLGNEITHK GLTADNEMYL
     RCKNLLQQVQ LDADPNTRVG ELGLGQQQLV EIAKALNKQV RLLILDEPTA SLTEKETEIL
     LNLIKDLKAH NIACIYISHK LNEVKAISDK ICVIRDGEHV GTKDASTMTE DDIITMMVGR
     EITSLYPHEP HEIKDEILRV ENLSAWHPIN THIKRVDNVS FSLHEGEILG VAGLVGSGRT
     DMVQCLFGSY EGKFEGNIFI NQKQVNIKNC AQAIEHKIVM VPEDRKKHGI VSIMGVGKNI
     TLSSLKSYCF GKMVVNEAKE EQIIGSAIKR LKVKTFSPDL PIGRLSGGNQ QKAILAKCLS
     LNPKILILDE PTRGIDVGAK YEIYKLINQL AQEGIAIIVI SSELPEVLGI SDRVLVMHQG
     KLKASLINTA LTQEQVMETA LKE