XYLG_SHIFL
ID XYLG_SHIFL Reviewed; 513 AA.
AC Q83J33; Q7BZ04;
DT 09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2003, sequence version 1.
DT 03-AUG-2022, entry version 144.
DE RecName: Full=Xylose import ATP-binding protein XylG {ECO:0000255|HAMAP-Rule:MF_01722};
DE EC=7.5.2.10 {ECO:0000255|HAMAP-Rule:MF_01722};
GN Name=xylG {ECO:0000255|HAMAP-Rule:MF_01722};
GN OrderedLocusNames=SF3611, S4158;
OS Shigella flexneri.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Shigella.
OX NCBI_TaxID=623;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=301 / Serotype 2a;
RX PubMed=12384590; DOI=10.1093/nar/gkf566;
RA Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J.,
RA Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L.,
RA Xue Y., Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H.,
RA Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J.;
RT "Genome sequence of Shigella flexneri 2a: insights into pathogenicity
RT through comparison with genomes of Escherichia coli K12 and O157.";
RL Nucleic Acids Res. 30:4432-4441(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700930 / 2457T / Serotype 2a;
RX PubMed=12704152; DOI=10.1128/iai.71.5.2775-2786.2003;
RA Wei J., Goldberg M.B., Burland V., Venkatesan M.M., Deng W., Fournier G.,
RA Mayhew G.F., Plunkett G. III, Rose D.J., Darling A., Mau B., Perna N.T.,
RA Payne S.M., Runyen-Janecky L.J., Zhou S., Schwartz D.C., Blattner F.R.;
RT "Complete genome sequence and comparative genomics of Shigella flexneri
RT serotype 2a strain 2457T.";
RL Infect. Immun. 71:2775-2786(2003).
CC -!- FUNCTION: Part of the ABC transporter complex XylFGH involved in xylose
CC import. Responsible for energy coupling to the transport system.
CC {ECO:0000255|HAMAP-Rule:MF_01722}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + D-xylose(out) + H2O = ADP + D-xylose(in) + H(+) +
CC phosphate; Xref=Rhea:RHEA:29899, ChEBI:CHEBI:15377,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474,
CC ChEBI:CHEBI:53455, ChEBI:CHEBI:456216; EC=7.5.2.10;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_01722};
CC -!- SUBUNIT: The complex is composed of two ATP-binding proteins (XylG),
CC two transmembrane proteins (XylH) and a solute-binding protein (XylF).
CC {ECO:0000255|HAMAP-Rule:MF_01722}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_01722}; Peripheral membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_01722}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. Xylose importer
CC (TC 3.A.1.2.4) family. {ECO:0000255|HAMAP-Rule:MF_01722}.
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DR EMBL; AE005674; AAN45060.1; -; Genomic_DNA.
DR EMBL; AE014073; AAP19129.1; -; Genomic_DNA.
DR RefSeq; NP_709353.1; NC_004337.2.
DR RefSeq; WP_001146516.1; NZ_WPGW01000060.1.
DR AlphaFoldDB; Q83J33; -.
DR SMR; Q83J33; -.
DR STRING; 198214.SF3611; -.
DR EnsemblBacteria; AAN45060; AAN45060; SF3611.
DR EnsemblBacteria; AAP19129; AAP19129; S4158.
DR GeneID; 1026269; -.
DR KEGG; sfl:SF3611; -.
DR KEGG; sft:NCTC1_03905; -.
DR KEGG; sfx:S4158; -.
DR PATRIC; fig|198214.7.peg.4263; -.
DR HOGENOM; CLU_000604_92_3_6; -.
DR OrthoDB; 551294at2; -.
DR Proteomes; UP000001006; Chromosome.
DR Proteomes; UP000002673; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015614; F:ABC-type D-xylose transporter activity; IEA:UniProtKB-EC.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; -; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR013455; ABC_transptr_xylose_ATP-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; SSF52540; 2.
DR TIGRFAMs; TIGR02633; xylG; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
DR PROSITE; PS51280; XYLG; 1.
PE 3: Inferred from homology;
KW ATP-binding; Cell inner membrane; Cell membrane; Membrane;
KW Nucleotide-binding; Reference proteome; Repeat; Sugar transport;
KW Translocase; Transport.
FT CHAIN 1..513
FT /note="Xylose import ATP-binding protein XylG"
FT /id="PRO_0000271515"
FT DOMAIN 5..242
FT /note="ABC transporter 1"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01722"
FT DOMAIN 259..505
FT /note="ABC transporter 2"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01722"
FT BINDING 37..44
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01722"
SQ SEQUENCE 513 AA; 56602 MW; FB7867EA11F81490 CRC64;
MPYLLEMKNI TKTFGSVKAI DNVSLRLNAG EIVSLCGENG SGKSTLMKVL CGIYPHGSYE
GEIIFAGEEI QASHIRDTER KGIAIIHQEL ALVKELTVLE NIFLGNEITH NGIMDYDLMT
LRYQKLLAQV SLSISPDTRV GDLGLGQQQL VEIAKALNKQ VRLLILDEPT ASLTEQETSV
LLDIIRDLQQ HGIACIYISH KLNEVKAISD TICVIRDGQH IGTRDAAGMS EDDIITMMVE
RELTAIYPNE PHTTGDEILR IEHLTAWHPV NRHIKRVNDV SFSLKRGEIL GIAGLVGAGR
TETIQCLFGV WPGQWEGKIY IDGKQVDIRN CQQAITQGIA MVPEDRKRDG IVPVMAVGKN
ITLAALNKFT GGISQLDDAA EQKCILESIQ QLKVKTSSPD LAIGRLSGGN QQKAILARCL
LLNPRILILD EPTRGIDIGA KYEIYKLINQ LVQQGIAVIV ISSELPEVLG LSDRVLVMHE
GKLKANLINH NLTQEQVMEA ALRSEHHVEK QSV
