XYLG_THEP3
ID XYLG_THEP3 Reviewed; 505 AA.
AC Q6VMN4;
DT 09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 74.
DE RecName: Full=Xylose import ATP-binding protein XylG {ECO:0000255|HAMAP-Rule:MF_01722};
DE EC=7.5.2.10 {ECO:0000255|HAMAP-Rule:MF_01722};
GN Name=xylG {ECO:0000255|HAMAP-Rule:MF_01722};
OS Thermoanaerobacter pseudethanolicus (strain ATCC 33223 / 39E) (Clostridium
OS thermohydrosulfuricum).
OC Bacteria; Firmicutes; Clostridia; Thermoanaerobacterales;
OC Thermoanaerobacteraceae; Thermoanaerobacter.
OX NCBI_TaxID=340099;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=15057456; DOI=10.1007/s00284-003-4202-6;
RA Erbeznik M., Hudson S.E., Herrman A.B., Strobel H.J.;
RT "Molecular analysis of the xylFGH operon, coding for xylose ABC transport,
RT in Thermoanaerobacter ethanolicus.";
RL Curr. Microbiol. 48:295-299(2004).
CC -!- FUNCTION: Part of the ABC transporter complex XylFGH involved in xylose
CC import. Responsible for energy coupling to the transport system.
CC {ECO:0000255|HAMAP-Rule:MF_01722}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + D-xylose(out) + H2O = ADP + D-xylose(in) + H(+) +
CC phosphate; Xref=Rhea:RHEA:29899, ChEBI:CHEBI:15377,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474,
CC ChEBI:CHEBI:53455, ChEBI:CHEBI:456216; EC=7.5.2.10;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_01722};
CC -!- SUBUNIT: The complex is composed of two ATP-binding proteins (XylG),
CC two transmembrane proteins (XylH) and a solute-binding protein (XylF).
CC {ECO:0000255|HAMAP-Rule:MF_01722}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01722};
CC Peripheral membrane protein {ECO:0000255|HAMAP-Rule:MF_01722}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. Xylose importer
CC (TC 3.A.1.2.4) family. {ECO:0000255|HAMAP-Rule:MF_01722}.
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DR EMBL; AY338239; AAQ93072.1; -; Genomic_DNA.
DR AlphaFoldDB; Q6VMN4; -.
DR SMR; Q6VMN4; -.
DR BRENDA; 7.5.2.10; 6284.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015614; F:ABC-type D-xylose transporter activity; IEA:UniProtKB-EC.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; -; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; SSF52540; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
DR PROSITE; PS51280; XYLG; 1.
PE 3: Inferred from homology;
KW ATP-binding; Cell membrane; Membrane; Nucleotide-binding; Repeat;
KW Sugar transport; Translocase; Transport.
FT CHAIN 1..505
FT /note="Xylose import ATP-binding protein XylG"
FT /id="PRO_0000271517"
FT DOMAIN 6..243
FT /note="ABC transporter 1"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01722"
FT DOMAIN 262..505
FT /note="ABC transporter 2"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01722"
FT BINDING 38..45
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01722"
SQ SEQUENCE 505 AA; 56706 MW; DAE3CC3FBFD7E92C CRC64;
MSEYILEMRN ITKEFPGVKA LDNVNFKVKR GEIHALVGEN GAGKSTLMKI LSGVYPYGTY
KGDIIIDGEV KQFRNIKDSE KSGIAIIYQE LTLVKYMTVG ENIFLGEEPV KGGIIDWMKV
YSETYRLLKE LQINVNPYTK VMNLGIGHQQ MVEIAKALSK KARILILDEP TSALTESETE
HLLNILKDLK KNGVTCIYIS HKLNEVFEIA DSITVLRDGK TIMTDKKENF TENKVISLMV
GRELTQRFPR AKHTPGEVVF EVKNYTVYDH EIPGKKIIDN VSFKARRGEI LGIAGLMGAG
RTELAASIFG AFKGRKEGEI YLNGKKIEIN TPSDAIKHGI AYLSEDRKRF GLVTLMDVQE
NIALPNYDRL SKFSIINNNA KIKHAEKYVK ELKIKTPTIR QRVANLSGGN QQKVVIAKWL
MSDPKVLILD EPTRGIDVGA KFEIYNLMNK LVDMGVCVIM ISSELPEILG MSDRILVIHE
GKINGEFPIE EADQEKIMYC ATGGK
