XYLG_YERPE
ID XYLG_YERPE Reviewed; 510 AA.
AC Q7CFR2; Q74QR4;
DT 09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 110.
DE RecName: Full=Xylose import ATP-binding protein XylG {ECO:0000255|HAMAP-Rule:MF_01722};
DE EC=7.5.2.10 {ECO:0000255|HAMAP-Rule:MF_01722};
GN Name=xylG {ECO:0000255|HAMAP-Rule:MF_01722};
GN OrderedLocusNames=YPO4036, y4055, YP_3398;
OS Yersinia pestis.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Yersinia.
OX NCBI_TaxID=632;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CO-92 / Biovar Orientalis;
RX PubMed=11586360; DOI=10.1038/35097083;
RA Parkhill J., Wren B.W., Thomson N.R., Titball R.W., Holden M.T.G.,
RA Prentice M.B., Sebaihia M., James K.D., Churcher C.M., Mungall K.L.,
RA Baker S., Basham D., Bentley S.D., Brooks K., Cerdeno-Tarraga A.-M.,
RA Chillingworth T., Cronin A., Davies R.M., Davis P., Dougan G., Feltwell T.,
RA Hamlin N., Holroyd S., Jagels K., Karlyshev A.V., Leather S., Moule S.,
RA Oyston P.C.F., Quail M.A., Rutherford K.M., Simmonds M., Skelton J.,
RA Stevens K., Whitehead S., Barrell B.G.;
RT "Genome sequence of Yersinia pestis, the causative agent of plague.";
RL Nature 413:523-527(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KIM10+ / Biovar Mediaevalis;
RX PubMed=12142430; DOI=10.1128/jb.184.16.4601-4611.2002;
RA Deng W., Burland V., Plunkett G. III, Boutin A., Mayhew G.F., Liss P.,
RA Perna N.T., Rose D.J., Mau B., Zhou S., Schwartz D.C., Fetherston J.D.,
RA Lindler L.E., Brubaker R.R., Plano G.V., Straley S.C., McDonough K.A.,
RA Nilles M.L., Matson J.S., Blattner F.R., Perry R.D.;
RT "Genome sequence of Yersinia pestis KIM.";
RL J. Bacteriol. 184:4601-4611(2002).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=91001 / Biovar Mediaevalis;
RX PubMed=15368893; DOI=10.1093/dnares/11.3.179;
RA Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D.,
RA Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L.,
RA Dai R., Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H.,
RA Wang J., Huang P., Yang R.;
RT "Complete genome sequence of Yersinia pestis strain 91001, an isolate
RT avirulent to humans.";
RL DNA Res. 11:179-197(2004).
CC -!- FUNCTION: Part of the ABC transporter complex XylFGH involved in xylose
CC import. Responsible for energy coupling to the transport system.
CC {ECO:0000255|HAMAP-Rule:MF_01722}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + D-xylose(out) + H2O = ADP + D-xylose(in) + H(+) +
CC phosphate; Xref=Rhea:RHEA:29899, ChEBI:CHEBI:15377,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474,
CC ChEBI:CHEBI:53455, ChEBI:CHEBI:456216; EC=7.5.2.10;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_01722};
CC -!- SUBUNIT: The complex is composed of two ATP-binding proteins (XylG),
CC two transmembrane proteins (XylH) and a solute-binding protein (XylF).
CC {ECO:0000255|HAMAP-Rule:MF_01722}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_01722}; Peripheral membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_01722}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. Xylose importer
CC (TC 3.A.1.2.4) family. {ECO:0000255|HAMAP-Rule:MF_01722}.
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DR EMBL; AL590842; CAL22612.1; -; Genomic_DNA.
DR EMBL; AE009952; AAM87599.1; -; Genomic_DNA.
DR EMBL; AE017042; AAS63559.1; -; Genomic_DNA.
DR PIR; AI0490; AI0490.
DR RefSeq; WP_002209590.1; NZ_WUCM01000040.1.
DR RefSeq; YP_002348899.1; NC_003143.1.
DR AlphaFoldDB; Q7CFR2; -.
DR SMR; Q7CFR2; -.
DR IntAct; Q7CFR2; 1.
DR STRING; 214092.YPO4036; -.
DR PaxDb; Q7CFR2; -.
DR DNASU; 1149002; -.
DR EnsemblBacteria; AAM87599; AAM87599; y4055.
DR EnsemblBacteria; AAS63559; AAS63559; YP_3398.
DR GeneID; 66843690; -.
DR KEGG; ype:YPO4036; -.
DR KEGG; ypk:y4055; -.
DR KEGG; ypm:YP_3398; -.
DR PATRIC; fig|214092.21.peg.4571; -.
DR eggNOG; COG1129; Bacteria.
DR HOGENOM; CLU_000604_92_3_6; -.
DR OMA; LPGGRMH; -.
DR Proteomes; UP000000815; Chromosome.
DR Proteomes; UP000001019; Chromosome.
DR Proteomes; UP000002490; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015614; F:ABC-type D-xylose transporter activity; IEA:UniProtKB-EC.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; -; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR013455; ABC_transptr_xylose_ATP-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; SSF52540; 2.
DR TIGRFAMs; TIGR02633; xylG; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
DR PROSITE; PS51280; XYLG; 1.
PE 3: Inferred from homology;
KW ATP-binding; Cell inner membrane; Cell membrane; Membrane;
KW Nucleotide-binding; Reference proteome; Repeat; Sugar transport;
KW Translocase; Transport.
FT CHAIN 1..510
FT /note="Xylose import ATP-binding protein XylG"
FT /id="PRO_0000271518"
FT DOMAIN 5..242
FT /note="ABC transporter 1"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01722"
FT DOMAIN 259..505
FT /note="ABC transporter 2"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01722"
FT BINDING 37..44
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01722"
SQ SEQUENCE 510 AA; 56249 MW; 0CA4A44A426A27E0 CRC64;
MPYLLEMKDI TKQFGVVKAV DNISLTLEAG QVLSLCGENG SGKSTLMKVL CGIYPVGSYQ
GEIIFSGETL QAKNIRETEQ KGIAIIHQEL ALVKQMSVLE NMFLGSEWGR FGIMDYDAMY
LRCQRMLAQV KLVVDPHTPV SELGLGQQQL VEIAKALNKQ VRLLVLDEPT ASLTESETAI
LLDIIRDLRN HGIACIYISH KLNEVKEISD HICVIRDGRH IGTRPASTMS EDDIIAMMVG
RELKELYPHE AHHIGEEILR VENLCAWHPV NRHIRRVDDV SFSLKRGEIL GIAGLVGSGR
TETVQCLFGV YPGRWQGDIF IKGQAATIRT CQQAMKLGIA MVPEDRKKDG IVPVMGVGAN
ITLAALDDFT GAFSLLDDAK EQSIIVQSLA RLKVKTSSSE LAIARLSGGN QQKAILAKCL
LLNPQILILD EPTRGIDIGA KYEIYKLINQ LVQQGIAVIV ISSELPEVLG LSDRVLVMHQ
GRIKADLINH NLTQEKVMEA ALRSETHVTS
