XYLH_SHIFL
ID XYLH_SHIFL Reviewed; 393 AA.
AC P0AGI7; P37389;
DT 20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT 20-DEC-2005, sequence version 1.
DT 25-MAY-2022, entry version 103.
DE RecName: Full=Xylose transport system permease protein XylH;
GN Name=xylH; OrderedLocusNames=SF3612, S4157;
OS Shigella flexneri.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Shigella.
OX NCBI_TaxID=623;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=301 / Serotype 2a;
RX PubMed=12384590; DOI=10.1093/nar/gkf566;
RA Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J.,
RA Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L.,
RA Xue Y., Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H.,
RA Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J.;
RT "Genome sequence of Shigella flexneri 2a: insights into pathogenicity
RT through comparison with genomes of Escherichia coli K12 and O157.";
RL Nucleic Acids Res. 30:4432-4441(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700930 / 2457T / Serotype 2a;
RX PubMed=12704152; DOI=10.1128/iai.71.5.2775-2786.2003;
RA Wei J., Goldberg M.B., Burland V., Venkatesan M.M., Deng W., Fournier G.,
RA Mayhew G.F., Plunkett G. III, Rose D.J., Darling A., Mau B., Perna N.T.,
RA Payne S.M., Runyen-Janecky L.J., Zhou S., Schwartz D.C., Blattner F.R.;
RT "Complete genome sequence and comparative genomics of Shigella flexneri
RT serotype 2a strain 2457T.";
RL Infect. Immun. 71:2775-2786(2003).
CC -!- FUNCTION: Part of the binding-protein-dependent transport system for D-
CC xylose. Probably responsible for the translocation of the substrate
CC across the membrane (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC permease family. AraH/RbsC subfamily. {ECO:0000305}.
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DR EMBL; AE005674; AAN45061.1; -; Genomic_DNA.
DR EMBL; AE014073; AAP19128.1; -; Genomic_DNA.
DR RefSeq; NP_709354.1; NC_004337.2.
DR RefSeq; WP_000045978.1; NZ_WPGW01000060.1.
DR AlphaFoldDB; P0AGI7; -.
DR STRING; 198214.SF3612; -.
DR EnsemblBacteria; AAN45061; AAN45061; SF3612.
DR EnsemblBacteria; AAP19128; AAP19128; S4157.
DR GeneID; 1026301; -.
DR GeneID; 67417213; -.
DR KEGG; sfl:SF3612; -.
DR KEGG; sfx:S4157; -.
DR PATRIC; fig|198214.7.peg.4264; -.
DR HOGENOM; CLU_028880_2_0_6; -.
DR OMA; FRTQAVQ; -.
DR OrthoDB; 1254678at2; -.
DR Proteomes; UP000001006; Chromosome.
DR Proteomes; UP000002673; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR InterPro; IPR001851; ABC_transp_permease.
DR Pfam; PF02653; BPD_transp_2; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW Sugar transport; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..393
FT /note="Xylose transport system permease protein XylH"
FT /id="PRO_0000060238"
FT TOPO_DOM 1..24
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 25..45
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 46..64
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 65..85
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 86..102
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 103..123
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 124..135
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 136..156
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 157..175
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 176..196
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 197..214
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 215..235
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 236..239
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 240..260
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 261..287
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 288..308
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 309..312
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 313..333
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 334..336
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 337..357
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 358..365
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 366..386
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 387..393
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
SQ SEQUENCE 393 AA; 41031 MW; 2BE94243CEDC2C9F CRC64;
MSKSNPSEVK LAVPTSGGFS GLKSLNLQVF VMIAAIIAIM LFFTWTTDGA YLSARNVSNL
LRQTAITGIL AVGMVFVIIS AEIDLSVGSM MGLLGGVAAI CDVWLGWPLP LTIIVTLVLG
LLLGAWNGWW VAYRKVPSFI VTLAGMLAFR GILIGITNGT TVSPTSAAMS QIGQSYLPAS
TGFIIGALGL MAFVGWQWRG RMRRQALGLQ SPASTAVVGR QALTAIIVLG AIWLLNDYRG
VPTPVLLLTL LLLGGMFMAT RTAFGRRIYA IGGNLEAARL SGINVERTKL AVFAINGLMV
AIAGLILSSR LGAGSPSAGN IAELDAIAAC VIGGTSLAGG VGSVAGAVMG AFIMASLDNG
MSMMDVPTFW QYIVKGAILL LAVWMDSATK RRS
