ID   XYLI_PSEPU              Reviewed;         264 AA.
AC   P49155;
DT   01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1996, sequence version 1.
DT   03-AUG-2022, entry version 81.
DE   RecName: Full=4-oxalocrotonate decarboxylase;
DE            Short=4-OD;
DE            EC=4.1.1.77;
GN   Name=xylI;
OS   Pseudomonas putida (Arthrobacter siderocapsulatus).
OG   Plasmid TOL pWW0.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=303;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 33015 / DSM 3931 / JCM 6156 / NCIMB 12182 / mt-2;
RX   PubMed=8510667; DOI=10.1007/bf00281605;
RA   Harayama S., Rekik M.;
RT   "Comparison of the nucleotide sequences of the meta-cleavage pathway genes
RT   of TOL plasmid pWW0 from Pseudomonas putida with other meta-cleavage genes
RT   suggests that both single and multiple nucleotide substitutions contribute
RT   to enzyme evolution.";
RL   Mol. Gen. Genet. 239:81-89(1993).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(3E)-2-oxohex-3-enedioate + H(+) = 2-oxopent-4-enoate + CO2;
CC         Xref=Rhea:RHEA:24260, ChEBI:CHEBI:11641, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:16526, ChEBI:CHEBI:64908; EC=4.1.1.77;
CC   -!- PATHWAY: Xenobiotic degradation; toluene degradation.
CC   -!- SIMILARITY: Belongs to the hydratase/decarboxylase family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; M94186; AAA25693.1; -; Genomic_DNA.
DR   PIR; S35224; S35224.
DR   RefSeq; NP_542860.1; NC_003350.1.
DR   RefSeq; WP_011005903.1; NC_003350.1.
DR   AlphaFoldDB; P49155; -.
DR   SMR; P49155; -.
DR   BioCyc; MetaCyc:MON-12752; -.
DR   UniPathway; UPA00273; -.
DR   GO; GO:0047437; F:4-oxalocrotonate decarboxylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0042203; P:toluene catabolic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.90.850.10; -; 1.
DR   InterPro; IPR017630; 4-oxalocrotonate_decarboxylase.
DR   InterPro; IPR036663; Fumarylacetoacetase_C_sf.
DR   SUPFAM; SSF56529; SSF56529; 1.
DR   TIGRFAMs; TIGR03218; catechol_dmpH; 1.
PE   3: Inferred from homology;
KW   Aromatic hydrocarbons catabolism; Lyase; Plasmid.
FT   CHAIN           1..264
FT                   /note="4-oxalocrotonate decarboxylase"
FT                   /id="PRO_0000066054"
SQ   SEQUENCE   264 AA;  28510 MW;  DDF93ACC910722F9 CRC64;
     MNRTLNREQV LALAEHIENA ELQAHDIHKV TNDYPEMTFA DAYTIQWEIR RRKEERGNKI
     VGLKMGLTSW AKMAQMGVET PIYGFLADYF SVPDGGVVDC SKLIHPKIEA EIAVVTKAPL
     VGPGCHIGDV IAAVDYVIPT VEVIDSRYEN FKFDLISVVA DNASSTRYIT GGRMANLEDV
     DLRTLGVVME KNGEVVELGA GAAVLGHPLS SVAMLANLLA ERGEHIPAGT FIMTGGITAA
     VAVAPGDNIT VRYQGLGSVS ARFV