XYLR_HAEIN
ID XYLR_HAEIN Reviewed; 387 AA.
AC P45043;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1995, sequence version 1.
DT 03-AUG-2022, entry version 127.
DE RecName: Full=Xylose operon regulatory protein;
GN Name=xylR; OrderedLocusNames=HI_1106;
OS Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC Pasteurellaceae; Haemophilus.
OX NCBI_TaxID=71421;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX PubMed=7542800; DOI=10.1126/science.7542800;
RA Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT Rd.";
RL Science 269:496-512(1995).
CC -!- FUNCTION: Regulatory protein for the xylBAFGHR operon. {ECO:0000250}.
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DR EMBL; L42023; AAC22761.1; -; Genomic_DNA.
DR PIR; H64182; H64182.
DR RefSeq; NP_439263.1; NC_000907.1.
DR RefSeq; WP_010869130.1; NC_000907.1.
DR AlphaFoldDB; P45043; -.
DR SMR; P45043; -.
DR STRING; 71421.HI_1106; -.
DR EnsemblBacteria; AAC22761; AAC22761; HI_1106.
DR KEGG; hin:HI_1106; -.
DR PATRIC; fig|71421.8.peg.1154; -.
DR eggNOG; COG1609; Bacteria.
DR eggNOG; COG2207; Bacteria.
DR HOGENOM; CLU_042405_1_0_6; -.
DR OMA; VEAAFMH; -.
DR PhylomeDB; P45043; -.
DR BioCyc; HINF71421:G1GJ1-1141-MON; -.
DR Proteomes; UP000000579; Chromosome.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IBA:GO_Central.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IBA:GO_Central.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR018060; HTH_AraC.
DR InterPro; IPR018062; HTH_AraC-typ_CS.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR028082; Peripla_BP_I.
DR InterPro; IPR020449; Tscrpt_reg_HTH_AraC-type.
DR Pfam; PF12833; HTH_18; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR PRINTS; PR00032; HTHARAC.
DR SMART; SM00342; HTH_ARAC; 1.
DR SUPFAM; SSF46689; SSF46689; 1.
DR SUPFAM; SSF53822; SSF53822; 1.
DR PROSITE; PS00041; HTH_ARAC_FAMILY_1; 1.
DR PROSITE; PS01124; HTH_ARAC_FAMILY_2; 1.
PE 3: Inferred from homology;
KW DNA-binding; Reference proteome; Transcription; Transcription regulation.
FT CHAIN 1..387
FT /note="Xylose operon regulatory protein"
FT /id="PRO_0000194600"
FT DOMAIN 288..386
FT /note="HTH araC/xylS-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00593"
FT DNA_BIND 305..326
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00593"
FT DNA_BIND 353..376
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00593"
SQ SEQUENCE 387 AA; 44932 MW; 4601673E413828CA CRC64;
MTEQYYKIAL LFNANKVYDR QVVEGIGQYI QASQCMWDIF VEDEFIYHTD TINQLSIDGI
IADFDDPKTV ELLQHTLIPT IAVGGSYKQA DFYPHFPYIA TDNMALVEMA LSHLQEKGLS
QFAFYGLQVN THKHWSIERR DAFVELMEKN HYPIYLYEGV QVHAQNWLEE QQKLIVWLKS
LPSHTGIIAV TDARARHLLQ ACEYSKIAVP EELCVVGIDN EELIQYLSRM SLSSVEQGTR
EIGYQAAKLL HKLLNGQKVS HTPILIPPIT VHSRNSTDYR SLTDPLVIQA MHYIRHRACH
RIKVGQVLDH LETSRSNLEQ RFKNEMNKTI HQVIHEEKIS RAKNLLQQTD ISIKEITEIC
GYPSIQYFYS VFKKEFEMTP KEFRLNC
