ID   XYLR_LACPE              Reviewed;         388 AA.
AC   P21940;
DT   01-MAY-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-1992, sequence version 2.
DT   25-MAY-2022, entry version 70.
DE   RecName: Full=Xylose repressor;
GN   Name=xylR;
OS   Lactiplantibacillus pentosus (Lactobacillus pentosus).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Lactiplantibacillus.
OX   NCBI_TaxID=1589;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=MD353;
RX   PubMed=1660563; DOI=10.1007/bf00290664;
RA   Lokman B.C., van Santen P., Verdoes J.C., Kruese J., Leer R.J., Posno M.,
RA   Pouwels P.H.;
RT   "Organization and characterization of three genes involved in D-xylose
RT   catabolism in Lactobacillus pentosus.";
RL   Mol. Gen. Genet. 230:161-169(1991).
CC   -!- FUNCTION: Transcriptional repressor of xylose-utilizing enzymes.
CC   -!- SIMILARITY: Belongs to the ROK (NagC/XylR) family. {ECO:0000305}.
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DR   EMBL; M57384; AAA25257.1; -; Genomic_DNA.
DR   PIR; S18560; S18560.
DR   AlphaFoldDB; P21940; -.
DR   SMR; P21940; -.
DR   STRING; 1589.GCA_001188985_00557; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR000600; ROK.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR18964; PTHR18964; 1.
DR   Pfam; PF00480; ROK; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF53067; SSF53067; 1.
DR   PROSITE; PS01125; ROK; 1.
PE   3: Inferred from homology;
KW   Carbohydrate metabolism; DNA-binding; Repressor; Transcription;
KW   Transcription regulation; Xylose metabolism.
FT   CHAIN           1..388
FT                   /note="Xylose repressor"
FT                   /id="PRO_0000095713"
FT   DNA_BIND        31..50
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   388 AA;  43604 MW;  2CB03049F6A75412 CRC64;
     MENRSISRTQ LRNRNLKLVL QQIINHPATS RIAISHELNL NKSTISSLYN SLSADHFIEE
     LGEGAASNVG GRKPIMARLN KKYGYTITFD LGYRQLHAMA NYLDAEIIDY QEIDTKGRPI
     EAMLDDCRHF VQEMQTQVHA IHGLLGICFS IHGIINDNQI VHSPWIDMHD IDIVKQFKAE
     FDVPVILENE ANLSAIYERD FNAGLDYRNS ITLSIHRGIG AGIILDKHLF RGKQGEAGEV
     GRSLTLLGPN TAGQSVESIC SEEAIINRVK RIKQDETTNR QTVVQLYQQH DREVERILSQ
     SCSVIAGLIY NVVTTLNPDA IFINSELLAE TPELLGDIQD NYRDIAQDQL PITLTKNTQF
     ATSLGGCSLI THYVLGMVDY ELQFKEAD