ID   XYLS2_PSEPU             Reviewed;         157 AA.
AC   Q05092;
DT   01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1994, sequence version 1.
DT   03-AUG-2022, entry version 91.
DE   RecName: Full=XylDLEGF operon transcriptional activator 2;
GN   Name=xylS2;
OS   Pseudomonas putida (Arthrobacter siderocapsulatus).
OG   Plasmid TOL pDK1, and Plasmid TOL pWW53.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=303;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=HS1, and MT53;
RX   PubMed=1331988; DOI=10.1093/nar/20.20.5476;
RA   Assinder S.J., de Marco P., Sayers J.R., Shaw L.E., Winson M.K.,
RA   Williams P.A.;
RT   "Identical resolvases are encoded by Pseudomonas TOL plasmids pWW53 and
RT   pDK1.";
RL   Nucleic Acids Res. 20:5476-5476(1992).
CC   -!- FUNCTION: Regulatory protein of the TOL plasmid xyl operons. XylS
CC       activates the xylXYZLTEGFJQKIH operon required for the degradation of
CC       toluene, m-xylene and p-xylene.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
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DR   EMBL; L02642; AAA71889.1; -; Unassigned_DNA.
DR   EMBL; L02643; AAA71891.1; -; Unassigned_DNA.
DR   PIR; S35486; S35486.
DR   AlphaFoldDB; Q05092; -.
DR   SMR; Q05092; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0009893; P:positive regulation of metabolic process; IEA:UniProt.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR018060; HTH_AraC.
DR   InterPro; IPR018062; HTH_AraC-typ_CS.
DR   Pfam; PF12833; HTH_18; 1.
DR   SMART; SM00342; HTH_ARAC; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   PROSITE; PS00041; HTH_ARAC_FAMILY_1; 1.
DR   PROSITE; PS01124; HTH_ARAC_FAMILY_2; 1.
PE   4: Predicted;
KW   Activator; Aromatic hydrocarbons catabolism; Cytoplasm; DNA-binding;
KW   Plasmid; Transcription; Transcription regulation.
FT   CHAIN           1..157
FT                   /note="XylDLEGF operon transcriptional activator 2"
FT                   /id="PRO_0000194603"
FT   DOMAIN          39..140
FT                   /note="HTH araC/xylS-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00593"
FT   DNA_BIND        56..77
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00593"
FT   DNA_BIND        107..130
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00593"
SQ   SEQUENCE   157 AA;  17895 MW;  A5FBB035F3F8F674 CRC64;
     MSMTLVAEHY TKIIATKLLE TLSSNVSRKG FVEGNPCFER VVQFIEENVK RSISLEQLAE
     LALMSPRSLY TMFEKHTGTT PMNYIRNRKL ECVRACLSNP TTNIRSITEV ALDYGFLHLG
     RFAEKYRSTF GELPSDTLSL HKMKCIDSRE SSLSSLF