ID   CAPE_STAAU              Reviewed;         440 AA.
AC   P39854;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   25-MAY-2022, entry version 62.
DE   RecName: Full=Protein CapE;
GN   Name=capE;
OS   Staphylococcus aureus.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=1280;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 49951 / M / NCTC 10649;
RX   PubMed=7961465; DOI=10.1128/jb.176.22.7005-7016.1994;
RA   Lin W.S., Cunneen T., Lee C.Y.;
RT   "Sequence analysis and molecular characterization of genes required for the
RT   biosynthesis of type 1 capsular polysaccharide in Staphylococcus aureus.";
RL   J. Bacteriol. 176:7005-7016(1994).
CC   -!- FUNCTION: Required for the biosynthesis of type 1 capsular
CC       polysaccharide.
CC   -!- PATHWAY: Capsule biogenesis; capsule polysaccharide biosynthesis.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; U10927; AAA64644.1; -; Genomic_DNA.
DR   AlphaFoldDB; P39854; -.
DR   SMR; P39854; -.
DR   UniPathway; UPA00934; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0045227; P:capsule polysaccharide biosynthetic process; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR029468; O-ag_pol_Wzy.
DR   Pfam; PF14296; O-ag_pol_Wzy; 1.
PE   4: Predicted;
KW   Capsule biogenesis/degradation; Cell membrane; Exopolysaccharide synthesis;
KW   Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..440
FT                   /note="Protein CapE"
FT                   /id="PRO_0000089312"
FT   TRANSMEM        7..27
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        31..51
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        60..80
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        102..122
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        141..161
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        179..199
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        204..224
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        249..269
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        324..344
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        360..380
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        382..402
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        409..429
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   440 AA;  50635 MW;  FDD89A1CB022BB34 CRC64;
     MKLKYKVILI INFVTVLFSI FTFIGYLNNL IGFRVVTISL CITIAMTVYL LYKKRKGFLL
     VYLIYLFLTN FGVFVTNIFL ANPLVEYHGD LSWYYINTSN LFSIATFAIL TFTILSNFIS
     VFSKINPSRK FDIKSKGNNL FYYTGILFII GFTIQFLFYI ITGRLAINTY GDYVSSIQEL
     PMYTYGIFFF SIGIAFAFSN VKKTHIKYLV IILTPQVLFF LITGNRGEVF YPILSALGVL
     IVRNYKIKWW MIITIVFTLF FVIPFIKVFR NMDSSSIEKV DINWFSSLVE IGYTLRPLGY
     VTRWIDGGES IVYGKSYLAP IQNIFSYIIP GLQPVNYEMV GYGFRYRLPG MGFNVIAEAY
     YNGAIVGVLI VMVLLVLLLW KFTNFKSFEM LSMGTAIVSV LINNIRNAFS FVPAYILIII
     VIVIILLFID SYLKKETKAD