ID   CAPH_STAAU              Reviewed;         355 AA.
AC   P39857;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   25-MAY-2022, entry version 54.
DE   RecName: Full=Capsular polysaccharide biosynthesis glycosyltransferase CapH;
DE            EC=2.4.-.-;
GN   Name=capH;
OS   Staphylococcus aureus.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=1280;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 49951 / M / NCTC 10649;
RX   PubMed=7961465; DOI=10.1128/jb.176.22.7005-7016.1994;
RA   Lin W.S., Cunneen T., Lee C.Y.;
RT   "Sequence analysis and molecular characterization of genes required for the
RT   biosynthesis of type 1 capsular polysaccharide in Staphylococcus aureus.";
RL   J. Bacteriol. 176:7005-7016(1994).
CC   -!- FUNCTION: Required for the biosynthesis of type 1 capsular
CC       polysaccharide.
CC   -!- PATHWAY: Capsule biogenesis; capsule polysaccharide biosynthesis.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase group 1 family.
CC       Glycosyltransferase 4 subfamily. {ECO:0000305}.
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DR   EMBL; U10927; AAA64647.1; -; Genomic_DNA.
DR   AlphaFoldDB; P39857; -.
DR   SMR; P39857; -.
DR   CAZy; GT4; Glycosyltransferase Family 4.
DR   UniPathway; UPA00934; -.
DR   GO; GO:0016757; F:glycosyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0045227; P:capsule polysaccharide biosynthetic process; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR001296; Glyco_trans_1.
DR   InterPro; IPR028098; Glyco_trans_4-like_N.
DR   Pfam; PF13439; Glyco_transf_4; 1.
DR   Pfam; PF00534; Glycos_transf_1; 1.
PE   3: Inferred from homology;
KW   Capsule biogenesis/degradation; Exopolysaccharide synthesis;
KW   Glycosyltransferase; Transferase.
FT   CHAIN           1..355
FT                   /note="Capsular polysaccharide biosynthesis
FT                   glycosyltransferase CapH"
FT                   /id="PRO_0000080293"
SQ   SEQUENCE   355 AA;  41410 MW;  13162200810C8EB5 CRC64;
     MIKVMHIFSR MNRGGAELRT MDTMKLLNRE FEFHVCATSG KRGELDDELE SMGITIHYLD
     IKKFSFPFKF IKLLKKKNID VVHSHILFMS GLIQLLSFSA NVRNRITHFR TSKDSKEQYN
     KIRKARNKVL KAIIEIFSTK ILYVSNIANR NLISMKLFPK KHKTIYNGFE ISNINKNFKK
     EENSFIYVGR FIHTKNQLFL LDVIEILKKE FNTNIEITFV GNIQTDYGKK FLSIANERGL
     NKNIKVIGEV NNPLDYLKTS EYFLFPSELE GLPGALIEAH HHNCIVISSN IKENSEVNQY
     FKDSSFELEL IPKTWASTIK KLISRKKHIS FNDSNVFDIN MTTQELKEIY MSKTL