ID   CAPM_STAAU              Reviewed;         380 AA.
AC   P39862;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   25-MAY-2022, entry version 52.
DE   RecName: Full=Capsular polysaccharide biosynthesis glycosyltransferase CapM;
DE            EC=2.4.-.-;
GN   Name=capM;
OS   Staphylococcus aureus.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=1280;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 49951 / M / NCTC 10649;
RX   PubMed=7961465; DOI=10.1128/jb.176.22.7005-7016.1994;
RA   Lin W.S., Cunneen T., Lee C.Y.;
RT   "Sequence analysis and molecular characterization of genes required for the
RT   biosynthesis of type 1 capsular polysaccharide in Staphylococcus aureus.";
RL   J. Bacteriol. 176:7005-7016(1994).
CC   -!- FUNCTION: Required for the biosynthesis of type 1 capsular
CC       polysaccharide.
CC   -!- PATHWAY: Capsule biogenesis; capsule polysaccharide biosynthesis.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase group 1 family.
CC       Glycosyltransferase 4 subfamily. {ECO:0000305}.
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DR   EMBL; U10927; AAA64652.1; -; Genomic_DNA.
DR   AlphaFoldDB; P39862; -.
DR   SMR; P39862; -.
DR   CAZy; GT4; Glycosyltransferase Family 4.
DR   UniPathway; UPA00934; -.
DR   GO; GO:0016757; F:glycosyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0045227; P:capsule polysaccharide biosynthetic process; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR001296; Glyco_trans_1.
DR   InterPro; IPR028098; Glyco_trans_4-like_N.
DR   Pfam; PF13477; Glyco_trans_4_2; 1.
DR   Pfam; PF00534; Glycos_transf_1; 1.
PE   3: Inferred from homology;
KW   Capsule biogenesis/degradation; Exopolysaccharide synthesis;
KW   Glycosyltransferase; Transferase.
FT   CHAIN           1..380
FT                   /note="Capsular polysaccharide biosynthesis
FT                   glycosyltransferase CapM"
FT                   /id="PRO_0000080294"
SQ   SEQUENCE   380 AA;  43166 MW;  0264E8376CD1A9EF CRC64;
     MKNQKIFHLV TVSKSIPLMR GQIEFLRKKN MDVHIVSSDG KELKQYDNEI AHVIPMKRDI
     ALFSDLKSLL KMILLFHKEK PFIVNSGTPK AGLIGTIAAF ITQRPIRIYT VRGLRLETVK
     GFKYFVLYLM EKIAMFCATD IIAISESLKH KIITSNLAKE NKITVLGFGS SNGIQFEKFQ
     LDNNKLEEKY HKLLNDNFVI GYVGRIVKDK GIHELIQSFK IIVSKGYNVK LLVIGSLETE
     NSIDESDYLF LTQNPNVVLI KHVSDPISFY NNMNVFVFPT HREGFGNVSI EAQALEVPVI
     TTNVTGAIDT VVNGETGFIV EKGDFKAIAE KIEKLINDES LRETIGHNGR KRVENKFSSQ
     IIWEELESMY NTFLKESEGK