ID   Y0074_EMENI             Reviewed;         554 AA.
AC   C8VTR6; Q5BGF9;
DT   19-OCT-2011, integrated into UniProtKB/Swiss-Prot.
DT   03-NOV-2009, sequence version 1.
DT   03-AUG-2022, entry version 58.
DE   RecName: Full=Putative acyl-coenzyme A synthetase;
DE            EC=6.2.1.-;
GN   ORFNames=AN10074;
OS   Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 /
OS   M139) (Aspergillus nidulans).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Nidulantes.
OX   NCBI_TaxID=227321;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX   PubMed=16372000; DOI=10.1038/nature04341;
RA   Galagan J.E., Calvo S.E., Cuomo C., Ma L.-J., Wortman J.R., Batzoglou S.,
RA   Lee S.-I., Bastuerkmen M., Spevak C.C., Clutterbuck J., Kapitonov V.,
RA   Jurka J., Scazzocchio C., Farman M.L., Butler J., Purcell S., Harris S.,
RA   Braus G.H., Draht O., Busch S., D'Enfert C., Bouchier C., Goldman G.H.,
RA   Bell-Pedersen D., Griffiths-Jones S., Doonan J.H., Yu J., Vienken K.,
RA   Pain A., Freitag M., Selker E.U., Archer D.B., Penalva M.A., Oakley B.R.,
RA   Momany M., Tanaka T., Kumagai T., Asai K., Machida M., Nierman W.C.,
RA   Denning D.W., Caddick M.X., Hynes M., Paoletti M., Fischer R., Miller B.L.,
RA   Dyer P.S., Sachs M.S., Osmani S.A., Birren B.W.;
RT   "Sequencing of Aspergillus nidulans and comparative analysis with A.
RT   fumigatus and A. oryzae.";
RL   Nature 438:1105-1115(2005).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX   PubMed=19146970; DOI=10.1016/j.fgb.2008.12.003;
RA   Wortman J.R., Gilsenan J.M., Joardar V., Deegan J., Clutterbuck J.,
RA   Andersen M.R., Archer D., Bencina M., Braus G., Coutinho P., von Dohren H.,
RA   Doonan J., Driessen A.J., Durek P., Espeso E., Fekete E., Flipphi M.,
RA   Estrada C.G., Geysens S., Goldman G., de Groot P.W., Hansen K.,
RA   Harris S.D., Heinekamp T., Helmstaedt K., Henrissat B., Hofmann G.,
RA   Homan T., Horio T., Horiuchi H., James S., Jones M., Karaffa L.,
RA   Karanyi Z., Kato M., Keller N., Kelly D.E., Kiel J.A., Kim J.M.,
RA   van der Klei I.J., Klis F.M., Kovalchuk A., Krasevec N., Kubicek C.P.,
RA   Liu B., Maccabe A., Meyer V., Mirabito P., Miskei M., Mos M., Mullins J.,
RA   Nelson D.R., Nielsen J., Oakley B.R., Osmani S.A., Pakula T., Paszewski A.,
RA   Paulsen I., Pilsyk S., Pocsi I., Punt P.J., Ram A.F., Ren Q., Robellet X.,
RA   Robson G., Seiboth B., van Solingen P., Specht T., Sun J.,
RA   Taheri-Talesh N., Takeshita N., Ussery D., vanKuyk P.A., Visser H.,
RA   van de Vondervoort P.J., de Vries R.P., Walton J., Xiang X., Xiong Y.,
RA   Zeng A.P., Brandt B.W., Cornell M.J., van den Hondel C.A., Visser J.,
RA   Oliver S.G., Turner G.;
RT   "The 2008 update of the Aspergillus nidulans genome annotation: a community
RT   effort.";
RL   Fungal Genet. Biol. 46:S2-13(2009).
CC   -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=EAA65777.1; Type=Erroneous gene model prediction; Note=The predicted gene AN0371 has been split into 2 genes: AN10067 and AN10074.; Evidence={ECO:0000305};
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DR   EMBL; AACD01000006; EAA65777.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; BN001308; CBF89623.1; -; Genomic_DNA.
DR   RefSeq; XP_657975.1; XM_652883.1.
DR   AlphaFoldDB; C8VTR6; -.
DR   SMR; C8VTR6; -.
DR   STRING; 162425.CADANIAP00002332; -.
DR   EnsemblFungi; CBF89623; CBF89623; ANIA_10074.
DR   EnsemblFungi; EAA65777; EAA65777; AN0371.2.
DR   GeneID; 2876146; -.
DR   KEGG; ani:AN0371.2; -.
DR   VEuPathDB; FungiDB:AN10074; -.
DR   eggNOG; KOG1176; Eukaryota.
DR   HOGENOM; CLU_413324_0_0_1; -.
DR   InParanoid; C8VTR6; -.
DR   OMA; GKIYMVD; -.
DR   OrthoDB; 683933at2759; -.
DR   Proteomes; UP000000560; Chromosome VIII.
DR   Proteomes; UP000005890; Unassembled WGS sequence.
DR   GO; GO:0016405; F:CoA-ligase activity; IBA:GO_Central.
DR   GO; GO:0019748; P:secondary metabolic process; IBA:GO_Central.
DR   Gene3D; 3.30.300.30; -; 1.
DR   Gene3D; 3.40.50.12780; -; 1.
DR   InterPro; IPR025110; AMP-bd_C.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig.
DR   InterPro; IPR042099; ANL_N_sf.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF13193; AMP-binding_C; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
PE   3: Inferred from homology;
KW   Ligase; Reference proteome.
FT   CHAIN           1..554
FT                   /note="Putative acyl-coenzyme A synthetase"
FT                   /id="PRO_0000413174"
FT   BINDING         195..206
FT                   /ligand="AMP"
FT                   /ligand_id="ChEBI:CHEBI:456215"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   554 AA;  60480 MW;  84369F0BEBE5BE23 CRC64;
     MQYLPEKDYE LPRLDLLTLL FESQLSLTTE STILHAEAAD PTNHITKAQA RTITKRLAHV
     FRSEFGIGAD GPGKDAVMCI SANQVLLPAV FCGIIGAGGV YTAASTALTA SEVSKQLRQS
     RSKVIVACPE NRAKARDAAR ECGIPPDRVL VLESMGHRRL LCQGNFGRNY LQATAELDWE
     RIADIDALEN TTICLLYSSG TTGPPKGVML SHMNLVSEAL FTQLVLRDSK EGKPHLNVPY
     RTVGHLPTAH IAGCLGCFIT PAVAGGTVYW MPRFNIDEFI DYCKKYAVTF LSTAPPVYHG
     IVRSDRVTDQ FKTLVRAESG AAPLSLELQE QAEKMLGCTI SQRWGMTEST GSVTTMPWGQ
     SDNTGGISPL LPNMRLRLVD ERMRDVRSGD EGEILLKGPM ITKGYFENPE ATAEAFTTDG
     WYKTGDIGVY KDGKIIMVDR KKELIKYKGL QVSPVEIEGF LLTHPGVADV AVVGARDPEA
     PGNELPRAYV VIKAGSSVSE AELKEYVKSN LAGHKQLRGG VVFIDEIPKS ASGKILRRIL
     RDQARSSAGR EAKL