ID   Y007_MYCLE              Reviewed;         303 AA.
AC   O32870;
DT   02-NOV-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   25-MAY-2022, entry version 95.
DE   RecName: Full=Uncharacterized protein ML0007;
GN   OrderedLocusNames=ML0007; ORFNames=MLB1770.07;
OS   Mycobacterium leprae (strain TN).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium.
OX   NCBI_TaxID=272631;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Fsihi H., Salazar L., Takiff H.E., Cole S.T.;
RL   Submitted (APR-1996) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TN;
RX   PubMed=11234002; DOI=10.1038/35059006;
RA   Cole S.T., Eiglmeier K., Parkhill J., James K.D., Thomson N.R.,
RA   Wheeler P.R., Honore N., Garnier T., Churcher C.M., Harris D.E.,
RA   Mungall K.L., Basham D., Brown D., Chillingworth T., Connor R.,
RA   Davies R.M., Devlin K., Duthoy S., Feltwell T., Fraser A., Hamlin N.,
RA   Holroyd S., Hornsby T., Jagels K., Lacroix C., Maclean J., Moule S.,
RA   Murphy L.D., Oliver K., Quail M.A., Rajandream M.A., Rutherford K.M.,
RA   Rutter S., Seeger K., Simon S., Simmonds M., Skelton J., Squares R.,
RA   Squares S., Stevens K., Taylor K., Whitehead S., Woodward J.R.,
RA   Barrell B.G.;
RT   "Massive gene decay in the leprosy bacillus.";
RL   Nature 409:1007-1011(2001).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: To M.tuberculosis Rv0007. {ECO:0000305}.
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DR   EMBL; Z70722; CAA94717.1; -; Genomic_DNA.
DR   EMBL; AL583917; CAC29515.1; -; Genomic_DNA.
DR   PIR; T10007; T10007.
DR   RefSeq; NP_301135.1; NC_002677.1.
DR   RefSeq; WP_010907460.1; NC_002677.1.
DR   AlphaFoldDB; O32870; -.
DR   STRING; 272631.ML0007; -.
DR   EnsemblBacteria; CAC29515; CAC29515; CAC29515.
DR   KEGG; mle:ML0007; -.
DR   PATRIC; fig|272631.5.peg.7; -.
DR   Leproma; ML0007; -.
DR   eggNOG; COG3266; Bacteria.
DR   HOGENOM; CLU_046697_0_1_11; -.
DR   OMA; ALFFIWM; -.
DR   Proteomes; UP000000806; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR021949; DUF3566_TM.
DR   Pfam; PF12089; DUF3566; 1.
PE   4: Predicted;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..303
FT                   /note="Uncharacterized protein ML0007"
FT                   /id="PRO_0000103638"
FT   TRANSMEM        205..225
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        264..284
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          1..89
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          132..159
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        52..89
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   303 AA;  32237 MW;  9761DD87391C11E4 CRC64;
     MTSPNESRAF NAADDLIGDG SVERAGLHRA TSVPGESSEG LQRGHSPEPN DSPPWQRGSA
     RASQSGYRPS DPLTTTRQSN PAPGANVRSN RFISGMTAPA LSGQLPKKNN STQALEPVLM
     SNEVPFTESY ASELPDLSGP VQRTVPCKPS PDRGSSTPRM GRLEITKVRG TGEIRSQISR
     RSHGPVRASM QIRRIDPWSM LKVSLLLSVA LFFVWMIAVA FLYLLLGGMG VWAKLNSNVG
     DLLNNTGGNS GELVSNSTIF GCAVLVGLVN IVLMTTMAAI AAFVYNLSSD LVGGVEVTLA
     DLD