Y014_MYCGE
ID Y014_MYCGE Reviewed; 623 AA.
AC P47260; Q49343;
DT 01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1996, sequence version 1.
DT 03-AUG-2022, entry version 139.
DE RecName: Full=Putative ABC transporter ATP-binding protein MG014;
GN OrderedLocusNames=MG014;
OS Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37)
OS (Mycoplasmoides genitalium).
OC Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX NCBI_TaxID=243273;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33530 / DSM 19775 / NCTC 10195 / G37;
RX PubMed=7569993; DOI=10.1126/science.270.5235.397;
RA Fraser C.M., Gocayne J.D., White O., Adams M.D., Clayton R.A.,
RA Fleischmann R.D., Bult C.J., Kerlavage A.R., Sutton G.G., Kelley J.M.,
RA Fritchman J.L., Weidman J.F., Small K.V., Sandusky M., Fuhrmann J.L.,
RA Nguyen D.T., Utterback T.R., Saudek D.M., Phillips C.A., Merrick J.M.,
RA Tomb J.-F., Dougherty B.A., Bott K.F., Hu P.-C., Lucier T.S.,
RA Peterson S.N., Smith H.O., Hutchison C.A. III, Venter J.C.;
RT "The minimal gene complement of Mycoplasma genitalium.";
RL Science 270:397-403(1995).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 227-333.
RC STRAIN=ATCC 33530 / DSM 19775 / NCTC 10195 / G37;
RX PubMed=8253680; DOI=10.1128/jb.175.24.7918-7930.1993;
RA Peterson S.N., Hu P.-C., Bott K.F., Hutchison C.A. III;
RT "A survey of the Mycoplasma genitalium genome by using random sequencing.";
RL J. Bacteriol. 175:7918-7930(1993).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000255|PROSITE-ProRule:PRU00441}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. {ECO:0000305}.
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DR EMBL; L43967; AAC71230.1; -; Genomic_DNA.
DR EMBL; U02235; AAA03387.1; -; Genomic_DNA.
DR PIR; E64201; E64201.
DR RefSeq; WP_010869290.1; NC_000908.2.
DR AlphaFoldDB; P47260; -.
DR SMR; P47260; -.
DR STRING; 243273.MG_014; -.
DR EnsemblBacteria; AAC71230; AAC71230; MG_014.
DR KEGG; mge:MG_014; -.
DR eggNOG; COG1132; Bacteria.
DR HOGENOM; CLU_000604_84_3_14; -.
DR OMA; STLAICW; -.
DR OrthoDB; 643917at2; -.
DR BioCyc; MGEN243273:G1GJ2-16-MON; -.
DR Proteomes; UP000000807; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0042626; F:ATPase-coupled transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0055085; P:transmembrane transport; IBA:GO_Central.
DR Gene3D; 1.20.1560.10; -; 1.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011527; ABC1_TM_dom.
DR InterPro; IPR036640; ABC1_TM_sf.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR039421; Type_1_exporter.
DR PANTHER; PTHR24221; PTHR24221; 1.
DR Pfam; PF00664; ABC_membrane; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR SUPFAM; SSF90123; SSF90123; 1.
DR PROSITE; PS50929; ABC_TM1F; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 3: Inferred from homology;
KW ATP-binding; Cell membrane; Membrane; Nucleotide-binding;
KW Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..623
FT /note="Putative ABC transporter ATP-binding protein MG014"
FT /id="PRO_0000093235"
FT TRANSMEM 27..47
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 81..101
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 157..177
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 181..201
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 266..286
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 307..327
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT DOMAIN 16..325
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT DOMAIN 365..611
FT /note="ABC transporter"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT BINDING 400..407
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT CONFLICT 331..333
FT /note="FNR -> LIV (in Ref. 2; AAA03387)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 623 AA; 69537 MW; F5D46215C9A95DDB CRC64;
MGLVLKEFNN KIRTALILAP FFTFAQIVID LIIPSFLASA ISVVFSIDKL KQDESGGKTI
SVDFIGGANI NFANVREAQI VLATTVILLA LCGLFFGLIS IYCASYVSAN TSFLLRKKIF
AKLMRITTPS HDHYGSSTLL VRLTNDVYLM EVIAFDFLRL IIRAPLLFIG GLVFAVTTNQ
DMSISLLITF PLILLVIGIL NRKSIPLFKE NQKSVDKINE RVEEDVSGYK VIQSFNLHSF
TNNKFKIANE GWKKNSTSSL FINSLNIPFT FFLSSLTIII ALLLVFQLDS SVSVDPLPQD
AAIRPNIFAF FQYNFYIVLG FILTSLTMVN FNRSRVALGR IKDILSQPEI KTITNKDQKE
LLPTLEFRNI SFGLGNKNNN NFLQNLSFKF EAYKTYGIVG PTGSGKSLIA NIIGGLYEPN
EGEILIGGEK IQSIDSLYLS EMIGIVFQQN ILFKGTISSN IKIGIETRSD WKNQSDLQKN
EAMKNAAKIA CADTFIEKFS DSYDHNVEQL GKNLSGGQKQ RVAIARTLIT KPRILVFDDS
MSALDALTEK KVRENIENDL KLTTKIIISQ NINSIKHADK ILVIDNGRIV GFDSDQKLMK
NCSLYQKMKE SQKDLGGDFD AVN
