ID   Y015_CLOK5              Reviewed;         904 AA.
AC   A5N466;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   10-JUL-2007, sequence version 1.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=UPF0182 protein CKL_0015 {ECO:0000255|HAMAP-Rule:MF_01600};
GN   OrderedLocusNames=CKL_0015;
OS   Clostridium kluyveri (strain ATCC 8527 / DSM 555 / NCIMB 10680).
OC   Bacteria; Firmicutes; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=431943;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8527 / DSM 555 / NCIMB 10680;
RX   PubMed=18218779; DOI=10.1073/pnas.0711093105;
RA   Seedorf H., Fricke W.F., Veith B., Brueggemann H., Liesegang H.,
RA   Strittmatter A., Miethke M., Buckel W., Hinderberger J., Li F.,
RA   Hagemeier C., Thauer R.K., Gottschalk G.;
RT   "The genome of Clostridium kluyveri, a strict anaerobe with unique
RT   metabolic features.";
RL   Proc. Natl. Acad. Sci. U.S.A. 105:2128-2133(2008).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01600};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01600}.
CC   -!- SIMILARITY: Belongs to the UPF0182 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01600}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000673; EDK32097.1; -; Genomic_DNA.
DR   RefSeq; WP_011988623.1; NC_009706.1.
DR   AlphaFoldDB; A5N466; -.
DR   SMR; A5N466; -.
DR   STRING; 431943.CKL_0015; -.
DR   EnsemblBacteria; EDK32097; EDK32097; CKL_0015.
DR   KEGG; ckl:CKL_0015; -.
DR   eggNOG; COG1615; Bacteria.
DR   HOGENOM; CLU_007733_0_0_9; -.
DR   OMA; HLRYPQD; -.
DR   OrthoDB; 170146at2; -.
DR   Proteomes; UP000002411; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   HAMAP; MF_01600; UPF0182; 1.
DR   InterPro; IPR005372; UPF0182.
DR   PANTHER; PTHR39344; PTHR39344; 1.
DR   Pfam; PF03699; UPF0182; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..904
FT                   /note="UPF0182 protein CKL_0015"
FT                   /id="PRO_0000335545"
FT   TRANSMEM        9..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        47..67
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        96..116
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        157..177
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        208..228
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        253..273
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        279..299
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
SQ   SEQUENCE   904 AA;  104290 MW;  1DACE6F28C627BD3 CRC64;
     MKRKMLWSSL IVILFVCILF LNKIVDFIIN VEWYKEVGYL TVYFTKLIAI CKLMIPLFII
     IYISIVLYWR SLRLSIIKYR RAFEVNNDKV KNEKRIFIIV NLIVSFLFSY AFAATYWYRI
     LQFNNSVPFN IKDPILNLDV SFYIFKLPLI QSLHSMILSL IIFLGLITLV TYFTLSVKDK
     VIWRNFKKDS GKIDILNSGI TRFAGKQLAV LAALVMICVS IGYILKCIGL VYSQKGVTFG
     AGYTDAHVSL LLYKIIAAAS IISAVIIFIS ILVSKVKPII VSITVIVALI LIKSLSYTVV
     QNFIVKSNQK TLEQPYIKYN IDYTRKAFNI ENIDANPFQV KDNLTSQDID NNMDTINNIR
     INSFEPTLEF YNQVQIIRYY YKFNNIDVDR YNINGKFNQI FIGTREINTK AIDPNTWQNR
     HLIYTHGYGI VMNKVNSVTS EGQPNFVIKD MPPQNSTDIK LDNARIYFGE KTDDYAIVDT
     KLKEFDYPKG SENATNNYDG SAGIKLGFIN RILFAINQKD INFLLSRDIL KESKILINRS
     IKDRVSKIAP FLNYDSDPYI VMSGGKLYWI LDGYTVSDRY PFAQPQNNLN YIRNSVKVTV
     DAENGNVNFY IMDKSDPIVQ SYAKIFPDLF KDINKLPSDI VQHFKYPKDL FNIQCSVLGK
     YHVTDPGVFY SGEDLWEVAK NQKQVSGEKY SMESSYMVMK LPNEQKEEMI LLQYFNMRDK
     DNMVALFGAR MDGENYGKMV LYKFPAEKTV YSPYLFKQKL NQDTTISSQL SLWNKDGSEV
     QFGDTIIVPI NQSLVYVEPM YLRASGKEGI PEMKRVIVSY SDKMVLAESI DDALQQIFSY
     KQDYNQENSN ESQIETPSYD INAEKLKEAK SLYEQALEAQ KNGDWSKYGE NIKKLGDIID
     SLQK