ID   Y018_CLOBJ              Reviewed;         893 AA.
AC   C1FPI3;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   26-MAY-2009, sequence version 1.
DT   25-MAY-2022, entry version 54.
DE   RecName: Full=UPF0182 protein CLM_0018 {ECO:0000255|HAMAP-Rule:MF_01600};
GN   OrderedLocusNames=CLM_0018;
OS   Clostridium botulinum (strain Kyoto / Type A2).
OC   Bacteria; Firmicutes; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=536232;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Kyoto / Type A2;
RA   Shrivastava S., Brinkac L.M., Brown J.L., Bruce D., Detter C.C.,
RA   Johnson E.A., Munk C.A., Smith L.A., Smith T.J., Sutton G., Brettin T.S.;
RT   "Genome sequence of Clostridium botulinum A2 Kyoto.";
RL   Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01600};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01600}.
CC   -!- SIMILARITY: Belongs to the UPF0182 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01600}.
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DR   EMBL; CP001581; ACO84722.1; -; Genomic_DNA.
DR   RefSeq; WP_012704378.1; NC_012563.1.
DR   AlphaFoldDB; C1FPI3; -.
DR   SMR; C1FPI3; -.
DR   STRING; 536232.CLM_0018; -.
DR   EnsemblBacteria; ACO84722; ACO84722; CLM_0018.
DR   KEGG; cby:CLM_0018; -.
DR   eggNOG; COG1615; Bacteria.
DR   HOGENOM; CLU_007733_0_0_9; -.
DR   OMA; HLRYPQD; -.
DR   Proteomes; UP000001374; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   HAMAP; MF_01600; UPF0182; 1.
DR   InterPro; IPR005372; UPF0182.
DR   PANTHER; PTHR39344; PTHR39344; 1.
DR   Pfam; PF03699; UPF0182; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..893
FT                   /note="UPF0182 protein CLM_0018"
FT                   /id="PRO_1000185783"
FT   TRANSMEM        9..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        49..69
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        94..114
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        154..174
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        202..222
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        246..266
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        273..293
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
SQ   SEQUENCE   893 AA;  104073 MW;  73B7D1E67AF5BD8F CRC64;
     MKNKKALFIP LFIIILFIAF FNKIINFIIN IKWFKEVNYL AVYFTKMRAI IILMIPIFII
     FFISIWMYYK SLIINKNKSV VDIGLNKNNY GKKLFFIFNF IVSIFLAYIF SSSYWYRILQ
     FNNSVDFNVK DPIFFKDVSF YIFKLPLFES LYKVIISLLL FLVITTFIAY FILEAKYKIQ
     SRKDINLKNI NHGIKSFAGK QLAIVSGLII LFISFGHLIK IWNLVYSSNG VSFGASYTDV
     HATLLFYKII VVITLISSIV TLLSIVKGKF KPVSVCIGIT IFLIVSQNIA SFLVQNFIVK
     SNEKTLEQPY IKNNIDLTRK AFALDDIEIR DFDIKNDLQK QDIADNKASI DNVRINSFKP
     TLEFYNQVQI IRYYYTFNDI DIDRYNINGK YNQVFLAARE IDTDALNPNT WQNRHLIYTH
     GFGAVMNKVN SVTSEGQPDF VIKDIPPYNK TNIKLTNPRI YFGEKTNDYV IVNTKINEFD
     YPREDSNKTN KYNGHAGIKM SFINRLLFAI NKKDINFLLS KDIKKDSKII INRNIVERAK
     KIAPFLTYDS DPYMVIYNGK IYWIIDAYTT TNRYPYSEPY DSINYIRNSA KVVIDSVDGD
     TNFYITDKKD PIVNNYAKIF KGLFKEEKDA PKEIREHFRY PKDLFSIQSK VLGKYHVKDP
     GVFYNGEDLW EVSKDQKHVE GETNTNDAPY IIMKLPDQNK EEMVLLNYFN VMKKDNMIAL
     FGARMDGEQY GKKILYKLPS DKTVYSPYLF KQKINQDTNI SKELSLWNRE GSKVQYGDTI
     ILPIKNSLLY IEPLYLRASG KNSIPEMKRV ILSYNDKLVL SSSIQEGIKE IFNSKDNKIN
     DKNEKDSTKT IDDSKLKKAQ EYYNKAIEAQ KNGDWTKYGE NINELGNILN SIK