ID   Y022_SIFVH              Reviewed;         559 AA.
AC   Q914K8;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   03-AUG-2022, entry version 85.
DE   RecName: Full=Putative helicase 22;
DE            EC=3.6.4.-;
GN   Name=SIFV0022;
OS   Sulfolobus islandicus filamentous virus (isolate Iceland/Hveragerdi)
OS   (SIFV).
OC   Viruses; Adnaviria; Zilligvirae; Taleaviricota; Tokiviricetes;
OC   Ligamenvirales; Lipothrixviridae; Betalipothrixvirus.
OX   NCBI_TaxID=654908;
OH   NCBI_TaxID=43080; Sulfolobus islandicus.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=10662621; DOI=10.1006/viro.1999.0105;
RA   Arnold H.P., Zillig W., Ziese U., Holz I., Crosby M., Utterback T.,
RA   Weidmann J.F., Umayam L.A., Teffera K., Kristjanson J.K., Klenk H.P.,
RA   Nelson K.E., Fraser C.M.;
RT   "A novel lipothrixvirus, SIFV, of the extremely thermophilic crenarchaeon
RT   Sulfolobus.";
RL   Virology 267:252-266(2000).
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DR   EMBL; AF440571; AAL27733.1; -; Genomic_DNA.
DR   RefSeq; NP_445687.1; NC_003214.2.
DR   SMR; Q914K8; -.
DR   PRIDE; Q914K8; -.
DR   GeneID; 922314; -.
DR   KEGG; vg:922314; -.
DR   Proteomes; UP000007017; Genome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 2.
DR   InterPro; IPR006935; Helicase/UvrB_N.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF04851; ResIII; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding; Helicase; Hydrolase; Nucleotide-binding; Reference proteome.
FT   CHAIN           1..559
FT                   /note="Putative helicase 22"
FT                   /id="PRO_0000385375"
FT   DOMAIN          186..347
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00541"
FT   DOMAIN          410..552
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00542"
FT   MOTIF           300..303
FT                   /note="DEAH box"
FT   BINDING         199..206
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00541"
SQ   SEQUENCE   559 AA;  65148 MW;  D13D6CC769E65F29 CRC64;
     MTQNINKIYL PSPNKYLSRE DFLNYTNLMR EIANFDPSTK KWYINEYKIS RLTKDELKGI
     IDQIAEYIGN SIYNILSNYI KDDNNIINAY IKGNYIYIRD NLEKYKNLLT YKIKTFDYKE
     GKYTEEEILL AWQKSYGFVT LRGLYWKLKN IANFDLKPFT NLRFYDIQLK NFEMRNYQIN
     SIKSWVSDVN VIGNGIIKAP TGSGKSVIAI LSALEILKNK NNAKIVYAVN STTLLKQFQN
     FAKKEDLPFV LVSGEIDEIK KGERSDFIAL SISYYYSKKK RNEHEKLKEL VTNADLVIID
     EAHHTPANIV KSLLLDSPNS IRLGLSATPI REDGKELEIM GLLGKISFTI DYTELVRNRY
     LVPIEYIRYI PEIPKKLKLK IQDLDDNKDP ENFAKYYSSL LRSFEHSPNT NKQIISKIKQ
     LNQYPCLVIV RRIAIAKKLA EIMRENGIIA DWVSSKTKLE ERMEKIEALK NEKLQVLIST
     SLADEGLDIP NLRLVVLLTQ GKSRIKLIQR IGRVMRVSQN KRKGYILDVI YNHDLFIKQS
     VKKMNFIENE YNGIITIHY