ID   Y027_MYCA9              Reviewed;         299 AA.
AC   B1ME65;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   29-APR-2008, sequence version 1.
DT   03-AUG-2022, entry version 73.
DE   RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase MAB_0027c;
DE            EC=2.1.1.-;
GN   OrderedLocusNames=MAB_0027c;
OS   Mycobacteroides abscessus (strain ATCC 19977 / DSM 44196 / CIP 104536 / JCM
OS   13569 / NCTC 13031 / TMC 1543) (Mycobacterium abscessus).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacteroides; Mycobacteroides abscessus.
OX   NCBI_TaxID=561007;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 19977 / DSM 44196 / CIP 104536 / JCM 13569 / NCTC 13031 / TMC
RC   1543;
RX   PubMed=19543527; DOI=10.1371/journal.pone.0005660;
RA   Ripoll F., Pasek S., Schenowitz C., Dossat C., Barbe V., Rottman M.,
RA   Macheras E., Heym B., Herrmann J.L., Daffe M., Brosch R., Risler J.L.,
RA   Gaillard J.L.;
RT   "Non mycobacterial virulence genes in the genome of the emerging pathogen
RT   Mycobacterium abscessus.";
RL   PLoS ONE 4:E5660-E5660(2009).
CC   -!- FUNCTION: Exhibits S-adenosyl-L-methionine-dependent methyltransferase
CC       activity. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UPF0677 family. {ECO:0000305}.
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DR   EMBL; CU458896; CAM60129.1; -; Genomic_DNA.
DR   RefSeq; WP_005082857.1; NZ_MLCG01000007.1.
DR   AlphaFoldDB; B1ME65; -.
DR   SMR; B1ME65; -.
DR   EnsemblBacteria; CAM60129; CAM60129; MAB_0027c.
DR   GeneID; 66970414; -.
DR   KEGG; mab:MAB_0027c; -.
DR   OMA; NEQCAPA; -.
DR   Proteomes; UP000007137; Chromosome.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR011610; CHP00027_methylltransferase.
DR   InterPro; IPR007213; Ppm1/Ppm2/Tcmp.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   Pfam; PF04072; LCM; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   TIGRFAMs; TIGR00027; mthyl_TIGR00027; 1.
PE   3: Inferred from homology;
KW   Methyltransferase; S-adenosyl-L-methionine; Transferase.
FT   CHAIN           1..299
FT                   /note="Putative S-adenosyl-L-methionine-dependent
FT                   methyltransferase MAB_0027c"
FT                   /id="PRO_0000361119"
FT   BINDING         126
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
FT   BINDING         155..156
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   299 AA;  33446 MW;  AA18A3D68AE216A6 CRC64;
     MTRTDGDQWD IVSSVGFTAL MVSSFRALET TRTEPLIRDE YARAFVEASG EPRLTEALAA
     GTPESEWDTA TVYLVNHLAV RTKYFDEFFA AATGSGIQQV VILAAGLDSR VYRLPWPDGT
     VVYELDQPKV LEFKDHVLRE EHAVPLAERR EVAVDLRDDW IAALRTAGFD ATKPTAWLAE
     GLLAYLPGAA QDALFENITA HSAPGSFLAT EWRRRQATAG QWQDAVNKLK PEFIKDISIG
     SLIYDDERQD PIEWLREHGW QVDTANRLEQ AAAYGRPAPS EHSDVTSLWS DAYFITATR