ID   CAPPA_SULTO             Reviewed;         511 AA.
AC   Q96YS2;
DT   13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   25-MAY-2022, entry version 99.
DE   RecName: Full=Phosphoenolpyruvate carboxylase {ECO:0000255|HAMAP-Rule:MF_01904};
DE            Short=PEPC {ECO:0000255|HAMAP-Rule:MF_01904};
DE            Short=PEPCase {ECO:0000255|HAMAP-Rule:MF_01904};
DE            EC=4.1.1.31 {ECO:0000255|HAMAP-Rule:MF_01904};
GN   Name=ppcA {ECO:0000255|HAMAP-Rule:MF_01904}; OrderedLocusNames=STK_21010;
OS   Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)
OS   (Sulfolobus tokodaii).
OC   Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC   Sulfurisphaera.
OX   NCBI_TaxID=273063;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 16993 / JCM 10545 / NBRC 100140 / 7;
RX   PubMed=11572479; DOI=10.1093/dnares/8.4.123;
RA   Kawarabayasi Y., Hino Y., Horikawa H., Jin-no K., Takahashi M., Sekine M.,
RA   Baba S., Ankai A., Kosugi H., Hosoyama A., Fukui S., Nagai Y.,
RA   Nishijima K., Otsuka R., Nakazawa H., Takamiya M., Kato Y., Yoshizawa T.,
RA   Tanaka T., Kudoh Y., Yamazaki J., Kushida N., Oguchi A., Aoki K.,
RA   Masuda S., Yanagii M., Nishimura M., Yamagishi A., Oshima T., Kikuchi H.;
RT   "Complete genome sequence of an aerobic thermoacidophilic Crenarchaeon,
RT   Sulfolobus tokodaii strain7.";
RL   DNA Res. 8:123-140(2001).
CC   -!- FUNCTION: Catalyzes the irreversible beta-carboxylation of
CC       phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon
CC       dicarboxylic acid source for the tricarboxylic acid cycle.
CC       {ECO:0000255|HAMAP-Rule:MF_01904}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=oxaloacetate + phosphate = hydrogencarbonate +
CC         phosphoenolpyruvate; Xref=Rhea:RHEA:28370, ChEBI:CHEBI:16452,
CC         ChEBI:CHEBI:17544, ChEBI:CHEBI:43474, ChEBI:CHEBI:58702; EC=4.1.1.31;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01904};
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01904};
CC   -!- SUBUNIT: Homotetramer. {ECO:0000255|HAMAP-Rule:MF_01904}.
CC   -!- SIMILARITY: Belongs to the PEPCase type 2 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01904}.
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DR   EMBL; BA000023; BAB67205.1; -; Genomic_DNA.
DR   RefSeq; WP_010980180.1; NC_003106.2.
DR   AlphaFoldDB; Q96YS2; -.
DR   SMR; Q96YS2; -.
DR   STRING; 273063.STK_21010; -.
DR   EnsemblBacteria; BAB67205; BAB67205; STK_21010.
DR   GeneID; 1460173; -.
DR   KEGG; sto:STK_21010; -.
DR   PATRIC; fig|273063.9.peg.2393; -.
DR   eggNOG; arCOG04435; Archaea.
DR   OMA; QSAFRYD; -.
DR   OrthoDB; 23334at2157; -.
DR   Proteomes; UP000001015; Chromosome.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0008964; F:phosphoenolpyruvate carboxylase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0015977; P:carbon fixation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006107; P:oxaloacetate metabolic process; IEA:UniProtKB-UniRule.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR   HAMAP; MF_01904; PEPcase_type2; 1.
DR   InterPro; IPR007566; PEP_COase_arc-type.
DR   InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR   Pfam; PF14010; PEPcase_2; 1.
DR   PIRSF; PIRSF006677; UCP006677; 1.
DR   SUPFAM; SSF51621; SSF51621; 1.
DR   TIGRFAMs; TIGR02751; PEPCase_arch; 1.
PE   3: Inferred from homology;
KW   Carbon dioxide fixation; Lyase; Magnesium; Reference proteome.
FT   CHAIN           1..511
FT                   /note="Phosphoenolpyruvate carboxylase"
FT                   /id="PRO_0000309616"
SQ   SEQUENCE   511 AA;  58839 MW;  95930EE53A0623ED CRC64;
     MRKIPRTMST QHPDNARVPE WSRSEVISGE SEVIEAYLAY EHYEVDEVMW DAEGKDVDTH
     VVRKLLTQYP EFFKEKILGR DIFLTYRIPN PKIEGAEKKV FAETMESIPI TYDLAEKFFN
     TKPTPPVFEV ILPFTTDYKE LIAILKYYEV AIVNKENVKL VDDIYVKDLI GEINPKSIEI
     IPLIEDRDSM FKIDQIVGEY IKAMKPPYMR VFLARSDPAM NYGLISAVLS VKYALNRLGK
     IEKKYGIKIF PLIGVGSLPF RGHFNPMNFE KVIDEYRGVY TFTVQSAFKY DYEDNEVINA
     IRKINEREIS EFELLDEEEE KILHRIANVY TSSYQPIIES LADVINKIAL FLPRRRARKL
     HIGLFGYSRS TGKVTLPRAI TFTGALYSIG IPPELIGISS LSTLTEKEWN VLEKNYKYIK
     HDLQAAARFV SYESIDLMKE TWNVNEEIIK KIMEDLSYAE NTLNIKIGDS NSVGRKHALI
     SSLALIALKE GNIDEAKSYL LEMAKIRKSL G