ID   Y034_PYRHO              Reviewed;         335 AA.
AC   O57746;
DT   10-OCT-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   25-MAY-2022, entry version 102.
DE   RecName: Full=UPF0284 protein PH0034 {ECO:0000255|HAMAP-Rule:MF_01086};
GN   OrderedLocusNames=PH0034;
OS   Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC
OS   100139 / OT-3).
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Pyrococcus.
OX   NCBI_TaxID=70601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3;
RX   PubMed=9679194; DOI=10.1093/dnares/5.2.55;
RA   Kawarabayasi Y., Sawada M., Horikawa H., Haikawa Y., Hino Y., Yamamoto S.,
RA   Sekine M., Baba S., Kosugi H., Hosoyama A., Nagai Y., Sakai M., Ogura K.,
RA   Otsuka R., Nakazawa H., Takamiya M., Ohfuku Y., Funahashi T., Tanaka T.,
RA   Kudoh Y., Yamazaki J., Kushida N., Oguchi A., Aoki K., Yoshizawa T.,
RA   Nakamura Y., Robb F.T., Horikoshi K., Masuchi Y., Shizuya H., Kikuchi H.;
RT   "Complete sequence and gene organization of the genome of a hyper-
RT   thermophilic archaebacterium, Pyrococcus horikoshii OT3.";
RL   DNA Res. 5:55-76(1998).
CC   -!- SIMILARITY: Belongs to the UPF0284 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01086}.
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DR   EMBL; BA000001; BAA29102.1; -; Genomic_DNA.
DR   PIR; G71221; G71221.
DR   PDB; 3U4G; X-ray; 1.90 A; A=1-335.
DR   PDBsum; 3U4G; -.
DR   AlphaFoldDB; O57746; -.
DR   SMR; O57746; -.
DR   STRING; 70601.3256419; -.
DR   EnsemblBacteria; BAA29102; BAA29102; BAA29102.
DR   KEGG; pho:PH0034; -.
DR   eggNOG; arCOG04272; Archaea.
DR   OMA; TRWVAED; -.
DR   Proteomes; UP000000752; Chromosome.
DR   GO; GO:0008939; F:nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity; IEA:InterPro.
DR   CDD; cd02439; DMB-PRT_CobT; 1.
DR   Gene3D; 3.40.50.10210; -; 1.
DR   HAMAP; MF_01086; UPF0284; 1.
DR   InterPro; IPR003200; Nict_dMeBzImd_PRibTrfase.
DR   InterPro; IPR002805; Nict_dMeBzImd_PRibTrfase_arc.
DR   InterPro; IPR036087; Nict_dMeBzImd_PRibTrfase_sf.
DR   PANTHER; PTHR38811; PTHR38811; 1.
DR   SUPFAM; SSF52733; SSF52733; 1.
DR   TIGRFAMs; TIGR00303; TIGR00303; 1.
PE   1: Evidence at protein level;
KW   3D-structure.
FT   CHAIN           1..335
FT                   /note="UPF0284 protein PH0034"
FT                   /id="PRO_0000151058"
FT   STRAND          7..13
FT                   /evidence="ECO:0007829|PDB:3U4G"
FT   HELIX           16..19
FT                   /evidence="ECO:0007829|PDB:3U4G"
FT   STRAND          26..29
FT                   /evidence="ECO:0007829|PDB:3U4G"
FT   HELIX           31..34
FT                   /evidence="ECO:0007829|PDB:3U4G"
FT   HELIX           36..45
FT                   /evidence="ECO:0007829|PDB:3U4G"
FT   STRAND          46..48
FT                   /evidence="ECO:0007829|PDB:3U4G"
FT   STRAND          50..54
FT                   /evidence="ECO:0007829|PDB:3U4G"
FT   HELIX           66..76
FT                   /evidence="ECO:0007829|PDB:3U4G"
FT   STRAND          80..86
FT                   /evidence="ECO:0007829|PDB:3U4G"
FT   TURN            106..108
FT                   /evidence="ECO:0007829|PDB:3U4G"
FT   HELIX           115..129
FT                   /evidence="ECO:0007829|PDB:3U4G"
FT   TURN            130..132
FT                   /evidence="ECO:0007829|PDB:3U4G"
FT   STRAND          133..141
FT                   /evidence="ECO:0007829|PDB:3U4G"
FT   HELIX           145..155
FT                   /evidence="ECO:0007829|PDB:3U4G"
FT   HELIX           170..185
FT                   /evidence="ECO:0007829|PDB:3U4G"
FT   TURN            189..194
FT                   /evidence="ECO:0007829|PDB:3U4G"
FT   HELIX           196..203
FT                   /evidence="ECO:0007829|PDB:3U4G"
FT   HELIX           206..217
FT                   /evidence="ECO:0007829|PDB:3U4G"
FT   STRAND          220..227
FT                   /evidence="ECO:0007829|PDB:3U4G"
FT   HELIX           228..239
FT                   /evidence="ECO:0007829|PDB:3U4G"
FT   STRAND          247..252
FT                   /evidence="ECO:0007829|PDB:3U4G"
FT   HELIX           253..257
FT                   /evidence="ECO:0007829|PDB:3U4G"
FT   HELIX           263..270
FT                   /evidence="ECO:0007829|PDB:3U4G"
FT   STRAND          273..277
FT                   /evidence="ECO:0007829|PDB:3U4G"
FT   HELIX           287..290
FT                   /evidence="ECO:0007829|PDB:3U4G"
FT   HELIX           291..294
FT                   /evidence="ECO:0007829|PDB:3U4G"
FT   HELIX           303..312
FT                   /evidence="ECO:0007829|PDB:3U4G"
FT   HELIX           317..330
FT                   /evidence="ECO:0007829|PDB:3U4G"
SQ   SEQUENCE   335 AA;  36178 MW;  F14CC3F86AFE05EE CRC64;
     MKKVKSLFLL VLGNTEISTI PGISVAGATP ELTKITPVAD AEYLFYEKPL TIDTIPVTPE
     GHPTPAIITK AARELSNFPI LVVRGGTYLA PLIPHVHISN VVGRDFRREP ALPEVEVIIE
     RAKLLGKELE KIANEIVIGE STPGGTTTAQ AILWALGYEA KTSSASPENP QELKEKVIKE
     GFKRVGIEKG GLKDKPLEAL KEFGDPMIAT VLGLSLGFGG DVVLAGGTQM LAVSALLKSL
     GEDLSRFMIA TTRWVVEDPS ATFIETAREI GIISYVAELD FSKSKFKGLR DYERGYVKEG
     VGAGGATWLA VKAGYSPEDV SKKVEELYER LMGLR