ID   Y034_STRR6              Reviewed;         336 AA.
AC   Q8DRN6;
DT   16-AUG-2004, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 2.
DT   25-MAY-2022, entry version 92.
DE   RecName: Full=UPF0324 membrane protein spr0034;
GN   OrderedLocusNames=spr0034;
OS   Streptococcus pneumoniae (strain ATCC BAA-255 / R6).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=171101;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-255 / R6;
RX   PubMed=11544234; DOI=10.1128/jb.183.19.5709-5717.2001;
RA   Hoskins J., Alborn W.E. Jr., Arnold J., Blaszczak L.C., Burgett S.,
RA   DeHoff B.S., Estrem S.T., Fritz L., Fu D.-J., Fuller W., Geringer C.,
RA   Gilmour R., Glass J.S., Khoja H., Kraft A.R., Lagace R.E., LeBlanc D.J.,
RA   Lee L.N., Lefkowitz E.J., Lu J., Matsushima P., McAhren S.M., McHenney M.,
RA   McLeaster K., Mundy C.W., Nicas T.I., Norris F.H., O'Gara M., Peery R.B.,
RA   Robertson G.T., Rockey P., Sun P.-M., Winkler M.E., Yang Y.,
RA   Young-Bellido M., Zhao G., Zook C.A., Baltz R.H., Jaskunas S.R.,
RA   Rosteck P.R. Jr., Skatrud P.L., Glass J.I.;
RT   "Genome of the bacterium Streptococcus pneumoniae strain R6.";
RL   J. Bacteriol. 183:5709-5717(2001).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the UPF0324 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAK98838.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AE007317; AAK98838.1; ALT_INIT; Genomic_DNA.
DR   PIR; B97876; B97876.
DR   RefSeq; NP_357628.1; NC_003098.1.
DR   RefSeq; WP_000009141.1; NC_003098.1.
DR   AlphaFoldDB; Q8DRN6; -.
DR   STRING; 171101.spr0034; -.
DR   EnsemblBacteria; AAK98838; AAK98838; spr0034.
DR   GeneID; 60233119; -.
DR   KEGG; spr:spr0034; -.
DR   PATRIC; fig|171101.6.peg.40; -.
DR   eggNOG; COG2855; Bacteria.
DR   HOGENOM; CLU_033541_2_1_9; -.
DR   Proteomes; UP000000586; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   InterPro; IPR018383; UPF0324_pro.
DR   PANTHER; PTHR30106; PTHR30106; 1.
DR   Pfam; PF03601; Cons_hypoth698; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..336
FT                   /note="UPF0324 membrane protein spr0034"
FT                   /id="PRO_0000157463"
FT   TRANSMEM        65..84
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        91..113
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        118..140
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        153..175
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        211..233
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        249..271
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        286..305
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        312..334
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   336 AA;  36019 MW;  B7B738540438E7F7 CRC64;
     MSFLSKNGAG ILACLLISIL SWYLGGFFPV IGAPVFAIFI GMLLHPFLSS YKQLDAGLTF
     SSKKLLQYAV VLLGFGLNIS QVFAVGQSSL PVILSTISIA LIIAYLFQRF FALDTKLATL
     VGVGSSICGG SAIAATAPVI HAKEKEVAQA ISVIFFFNVL AALIFPTLGT WLHLSNEGFA
     LFAGTAVNDT SSVTAAASAW DSLYQSNTLE SATIVKLTRT LAIIPITLFL SYWQSRQQEN
     KQSLQLKKVF PLFILYFILA SLLTTLLTSL GVSSSFFTPL KQLSKFLIVM AMSAIGLKTN
     LVAMVKSSGK SILLGAICWI AIILTTLGMQ TLIGIF