ID   Y035_HAEIN              Reviewed;         551 AA.
AC   P44472;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   03-AUG-2022, entry version 119.
DE   RecName: Full=Putative transport protein HI_0035 {ECO:0000255|HAMAP-Rule:MF_01016};
GN   OrderedLocusNames=HI_0035;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01016};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01016}.
CC   -!- SIMILARITY: Belongs to the AAE transporter (TC 2.A.81) family. YidE
CC       subfamily. {ECO:0000255|HAMAP-Rule:MF_01016}.
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DR   EMBL; L42023; AAC21713.1; -; Genomic_DNA.
DR   PIR; I64140; I64140.
DR   RefSeq; NP_438208.1; NC_000907.1.
DR   RefSeq; WP_005693880.1; NC_000907.1.
DR   AlphaFoldDB; P44472; -.
DR   STRING; 71421.HI_0035; -.
DR   EnsemblBacteria; AAC21713; AAC21713; HI_0035.
DR   KEGG; hin:HI_0035; -.
DR   PATRIC; fig|71421.8.peg.35; -.
DR   eggNOG; COG2985; Bacteria.
DR   HOGENOM; CLU_035023_3_1_6; -.
DR   OMA; AMWLIRL; -.
DR   PhylomeDB; P44472; -.
DR   BioCyc; HINF71421:G1GJ1-35-MON; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR   Gene3D; 3.30.70.1450; -; 2.
DR   HAMAP; MF_01016; YidE; 1.
DR   InterPro; IPR006037; RCK_C.
DR   InterPro; IPR036721; RCK_C_sf.
DR   InterPro; IPR023018; Transpt_YidE_put.
DR   InterPro; IPR006512; YidE_YbjL.
DR   Pfam; PF06826; Asp-Al_Ex; 2.
DR   Pfam; PF02080; TrkA_C; 1.
DR   SUPFAM; SSF116726; SSF116726; 2.
DR   TIGRFAMs; TIGR01625; YidE_YbjL_dupl; 2.
DR   PROSITE; PS51202; RCK_C; 2.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Repeat; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..551
FT                   /note="Putative transport protein HI_0035"
FT                   /id="PRO_0000208801"
FT   TRANSMEM        4..24
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01016"
FT   TRANSMEM        28..48
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01016"
FT   TRANSMEM        65..85
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01016"
FT   TRANSMEM        95..115
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01016"
FT   TRANSMEM        157..177
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01016"
FT   TRANSMEM        370..390
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01016"
FT   TRANSMEM        402..424
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01016"
FT   TRANSMEM        438..458
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01016"
FT   TRANSMEM        463..483
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01016"
FT   TRANSMEM        492..512
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01016"
FT   TRANSMEM        529..549
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01016"
FT   DOMAIN          191..275
FT                   /note="RCK C-terminal 1"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01016"
FT   DOMAIN          277..360
FT                   /note="RCK C-terminal 2"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01016"
SQ   SEQUENCE   551 AA;  59014 MW;  4550021090CDFA1F CRC64;
     MSDIAITISL LALVAVIGLW IGHWKIRGVG LGIGGVLFGG IIVAHFTNQY GLKLDAHTLH
     FVQEFGLILF VYTIGIQVGP GFFSSLRKSG LKLNAFAILI ILLGSIAVVL VHKIADVPLD
     IALGIYSGAV TNTPALGAGQ QILAELGVPQ TTVTMGVSYA MAYPFGICGI LLAMWLIRLF
     FNVKVDDEAA RFNAESSQDK ESLHNISLKV TNQNLDGLTL IQIPGFSDEE VVCSRLKRDD
     MEIVPKASTE IRTNDILQLV GDDNSLAKMR LIIGHEVDAP TVAYSGEIRS ERVVVTNEKV
     LGKKIRALGI HQKYGVVISR LNRAGIELVP TGNTTLQFGD VLHMVGRSDV LNQAISVIGN
     AQQKLLQVQM LPVFIGIGLG VLVGSIPFYI PGFPVALKLG LAGGPLVVAL ILARIGTIGK
     LYWFMPPSAN LALREIGIVL FLAVVGLKSG GSFFDTLVNG SGLEWMGYGI FITFVPLIIV
     GTIARLYGKL NYLTICGLLA GSMTDPPALA FANEIKEDNG AAALSYATVY PLVMFLRIMS
     PQLLAVLLWA A