ID   Y035_HELPY              Reviewed;          97 AA.
AC   O24876;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   25-MAY-2022, entry version 113.
DE   RecName: Full=Nucleoid-associated protein HP_0035 {ECO:0000255|HAMAP-Rule:MF_00274};
GN   OrderedLocusNames=HP_0035;
OS   Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori).
OC   Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=85962;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700392 / 26695;
RX   PubMed=9252185; DOI=10.1038/41483;
RA   Tomb J.-F., White O., Kerlavage A.R., Clayton R.A., Sutton G.G.,
RA   Fleischmann R.D., Ketchum K.A., Klenk H.-P., Gill S.R., Dougherty B.A.,
RA   Nelson K.E., Quackenbush J., Zhou L., Kirkness E.F., Peterson S.N.,
RA   Loftus B.J., Richardson D.L., Dodson R.J., Khalak H.G., Glodek A.,
RA   McKenney K., FitzGerald L.M., Lee N., Adams M.D., Hickey E.K., Berg D.E.,
RA   Gocayne J.D., Utterback T.R., Peterson J.D., Kelley J.M., Cotton M.D.,
RA   Weidman J.F., Fujii C., Bowman C., Watthey L., Wallin E., Hayes W.S.,
RA   Borodovsky M., Karp P.D., Smith H.O., Fraser C.M., Venter J.C.;
RT   "The complete genome sequence of the gastric pathogen Helicobacter
RT   pylori.";
RL   Nature 388:539-547(1997).
RN   [2]
RP   X-RAY CRYSTALLOGRAPHY (1.78 ANGSTROMS).
RG   Midwest center for structural genomics (MCSG);
RT   "Crystal structure of uncharacterized protein HP0035 from Helicobacter
RT   pylori.";
RL   Submitted (JUL-2011) to the PDB data bank.
CC   -!- FUNCTION: Binds to DNA and alters its conformation. May be involved in
CC       regulation of gene expression, nucleoid organization and DNA
CC       protection. {ECO:0000255|HAMAP-Rule:MF_00274}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_00274}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, nucleoid {ECO:0000255|HAMAP-
CC       Rule:MF_00274}.
CC   -!- SIMILARITY: Belongs to the YbaB/EbfC family. {ECO:0000255|HAMAP-
CC       Rule:MF_00274}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE000511; AAD07104.1; -; Genomic_DNA.
DR   PIR; C64524; C64524.
DR   RefSeq; NP_206837.1; NC_000915.1.
DR   RefSeq; WP_000347915.1; NC_018939.1.
DR   PDB; 3F42; X-ray; 1.78 A; A/B=1-97.
DR   PDBsum; 3F42; -.
DR   AlphaFoldDB; O24876; -.
DR   SMR; O24876; -.
DR   DIP; DIP-3108N; -.
DR   MINT; O24876; -.
DR   STRING; 85962.C694_00165; -.
DR   PaxDb; O24876; -.
DR   EnsemblBacteria; AAD07104; AAD07104; HP_0035.
DR   KEGG; hpy:HP_0035; -.
DR   PATRIC; fig|85962.47.peg.36; -.
DR   eggNOG; COG0718; Bacteria.
DR   OMA; KSQAMGM; -.
DR   PhylomeDB; O24876; -.
DR   EvolutionaryTrace; O24876; -.
DR   Proteomes; UP000000429; Chromosome.
DR   GO; GO:0043590; C:bacterial nucleoid; IEA:UniProtKB-UniRule.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-UniRule.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.1310.10; -; 1.
DR   HAMAP; MF_00274; DNA_YbaB_EbfC; 1.
DR   InterPro; IPR036894; YbaB-like_sf.
DR   InterPro; IPR004401; YbaB/EbfC.
DR   Pfam; PF02575; YbaB_DNA_bd; 1.
DR   PIRSF; PIRSF004555; UCP004555; 1.
DR   SUPFAM; SSF82607; SSF82607; 1.
DR   TIGRFAMs; TIGR00103; DNA_YbaB_EbfC; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Cytoplasm; DNA-binding; Reference proteome.
FT   CHAIN           1..97
FT                   /note="Nucleoid-associated protein HP_0035"
FT                   /id="PRO_0000170399"
FT   HELIX           3..25
FT                   /evidence="ECO:0007829|PDB:3F42"
FT   STRAND          28..33
FT                   /evidence="ECO:0007829|PDB:3F42"
FT   HELIX           34..36
FT                   /evidence="ECO:0007829|PDB:3F42"
FT   STRAND          38..43
FT                   /evidence="ECO:0007829|PDB:3F42"
FT   STRAND          48..53
FT                   /evidence="ECO:0007829|PDB:3F42"
FT   HELIX           55..59
FT                   /evidence="ECO:0007829|PDB:3F42"
FT   HELIX           61..91
FT                   /evidence="ECO:0007829|PDB:3F42"
SQ   SEQUENCE   97 AA;  10724 MW;  11060AFF9957357D CRC64;
     MDFSQLGGLL DGMKKEFSQL EEKNKDTIHT SKSGGGMVSV SFNGLGELVD LQIDDSLLED
     KEAMQIYLMS ALNDGYKAVE ENRKNLAFNM LGNFAKL