ID   Y036_HAEIN              Reviewed;         592 AA.
AC   Q57335; O05006;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 125.
DE   RecName: Full=Uncharacterized ABC transporter ATP-binding protein HI_0036;
GN   OrderedLocusNames=HI_0036;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC       membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. {ECO:0000305}.
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DR   EMBL; L42023; AAC21714.1; -; Genomic_DNA.
DR   PIR; D64044; D64044.
DR   RefSeq; NP_438209.1; NC_000907.1.
DR   RefSeq; WP_005668011.1; NC_000907.1.
DR   AlphaFoldDB; Q57335; -.
DR   SMR; Q57335; -.
DR   STRING; 71421.HI_0036; -.
DR   EnsemblBacteria; AAC21714; AAC21714; HI_0036.
DR   KEGG; hin:HI_0036; -.
DR   PATRIC; fig|71421.8.peg.36; -.
DR   eggNOG; COG4178; Bacteria.
DR   HOGENOM; CLU_007587_6_2_6; -.
DR   OMA; FRYGLVH; -.
DR   PhylomeDB; Q57335; -.
DR   BioCyc; HINF71421:G1GJ1-36-MON; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR   GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IBA:GO_Central.
DR   GO; GO:0042626; F:ATPase-coupled transmembrane transporter activity; IBA:GO_Central.
DR   Gene3D; 1.20.1560.10; -; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR011527; ABC1_TM_dom.
DR   InterPro; IPR036640; ABC1_TM_sf.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF06472; ABC_membrane_2; 1.
DR   Pfam; PF00005; ABC_tran; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   SUPFAM; SSF90123; SSF90123; 1.
DR   PROSITE; PS50929; ABC_TM1F; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cell inner membrane; Cell membrane; Membrane;
KW   Nucleotide-binding; Reference proteome; Transmembrane; Transmembrane helix;
KW   Transport.
FT   CHAIN           1..592
FT                   /note="Uncharacterized ABC transporter ATP-binding protein
FT                   HI_0036"
FT                   /id="PRO_0000093198"
FT   TRANSMEM        12..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        58..78
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        102..122
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        191..211
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        214..234
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        299..319
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   DOMAIN          58..358
FT                   /note="ABC transmembrane type-1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   DOMAIN          391..592
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   BINDING         424..431
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ   SEQUENCE   592 AA;  67904 MW;  6F2E91C0C0708237 CRC64;
     MDYSQEAITS LIWILQTLAI TSVVFSFGIF LLVRFTQWGK QFWMFAGGYL SPKRSIKPIL
     FFLLIVAMTL LSVRISLVNS EWYKNMYTSL QEFNEHVFWQ QMGLFCVIAA SSVSAALVSY
     YLEQRFVINW IEWLNEQLVN KWMAHRAYYK TQYLSENLDN PDQRIQQDVQ SYVKTTLSLS
     TGVIDAVTSM ISYTILLWGL AGPMIVLGVE IPHMMVFLVF GYVIFTTLIA FWLGRPLISL
     NFINERLNAN YRYSLIRIKE YAESIAFYAG EKVEKNQLYQ QFNAVIHNMW VIIFRTLKFS
     GFNLVVSQIS VVFPLLIQVG RYFEKQIKLG DLMQTLQVFG QLHANLSFFR STYDNFASYK
     ATLDRLTGFC YAIEKANNKS QTQIHNHPTD VIFKNLSIQN PLGHTLIKHL NITLPQGTSL
     LIQGKSGAGK TTLLRTIAGL WSYAEGEINC PTHNQLFLSQ KPYVPQGNLM SALAYPNNAD
     NISHTQAVEI LNKVQLGHLA EQLEKEQDWT RILSLGEQQR LAFARLILHK PAVAFLDEAT
     ASMDEGLEFS MYQLLQQELP QTTIISVGHR STLKTLHQQQ LILQDKGQWQ VL