ID   CAPP_ACTP2              Reviewed;         879 AA.
AC   A3MZ57;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   03-APR-2007, sequence version 1.
DT   03-AUG-2022, entry version 95.
DE   RecName: Full=Phosphoenolpyruvate carboxylase {ECO:0000255|HAMAP-Rule:MF_00595};
DE            Short=PEPC {ECO:0000255|HAMAP-Rule:MF_00595};
DE            Short=PEPCase {ECO:0000255|HAMAP-Rule:MF_00595};
DE            EC=4.1.1.31 {ECO:0000255|HAMAP-Rule:MF_00595};
GN   Name=ppc {ECO:0000255|HAMAP-Rule:MF_00595}; OrderedLocusNames=APL_0339;
OS   Actinobacillus pleuropneumoniae serotype 5b (strain L20).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Actinobacillus.
OX   NCBI_TaxID=416269;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=L20;
RX   PubMed=18065534; DOI=10.1128/jb.01845-07;
RA   Foote S.J., Bosse J.T., Bouevitch A.B., Langford P.R., Young N.M.,
RA   Nash J.H.E.;
RT   "The complete genome sequence of Actinobacillus pleuropneumoniae L20
RT   (serotype 5b).";
RL   J. Bacteriol. 190:1495-1496(2008).
CC   -!- FUNCTION: Forms oxaloacetate, a four-carbon dicarboxylic acid source
CC       for the tricarboxylic acid cycle. {ECO:0000255|HAMAP-Rule:MF_00595}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=oxaloacetate + phosphate = hydrogencarbonate +
CC         phosphoenolpyruvate; Xref=Rhea:RHEA:28370, ChEBI:CHEBI:16452,
CC         ChEBI:CHEBI:17544, ChEBI:CHEBI:43474, ChEBI:CHEBI:58702; EC=4.1.1.31;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00595};
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00595};
CC   -!- SIMILARITY: Belongs to the PEPCase type 1 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00595}.
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DR   EMBL; CP000569; ABN73443.1; -; Genomic_DNA.
DR   RefSeq; WP_011848359.1; NC_009053.1.
DR   AlphaFoldDB; A3MZ57; -.
DR   SMR; A3MZ57; -.
DR   STRING; 416269.APL_0339; -.
DR   EnsemblBacteria; ABN73443; ABN73443; APL_0339.
DR   KEGG; apl:APL_0339; -.
DR   PATRIC; fig|416269.6.peg.348; -.
DR   eggNOG; COG2352; Bacteria.
DR   HOGENOM; CLU_006557_2_0_6; -.
DR   OMA; PWVFGWT; -.
DR   Proteomes; UP000001432; Chromosome.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0008964; F:phosphoenolpyruvate carboxylase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0015977; P:carbon fixation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006107; P:oxaloacetate metabolic process; IEA:UniProtKB-UniRule.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR   HAMAP; MF_00595; PEPcase_type1; 1.
DR   InterPro; IPR021135; PEP_COase.
DR   InterPro; IPR022805; PEP_COase_bac/pln-type.
DR   InterPro; IPR018129; PEP_COase_Lys_AS.
DR   InterPro; IPR033129; PEPCASE_His_AS.
DR   InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR   PANTHER; PTHR30523; PTHR30523; 1.
DR   Pfam; PF00311; PEPcase; 1.
DR   PRINTS; PR00150; PEPCARBXLASE.
DR   SUPFAM; SSF51621; SSF51621; 1.
DR   PROSITE; PS00781; PEPCASE_1; 1.
DR   PROSITE; PS00393; PEPCASE_2; 1.
PE   3: Inferred from homology;
KW   Carbon dioxide fixation; Lyase; Magnesium; Reference proteome.
FT   CHAIN           1..879
FT                   /note="Phosphoenolpyruvate carboxylase"
FT                   /id="PRO_1000025543"
FT   ACT_SITE        138
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00595"
FT   ACT_SITE        545
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00595"
SQ   SEQUENCE   879 AA;  99144 MW;  4311EE8513C0894A CRC64;
     MNQPYSAMRN NIHMLGDFLG ETIREAQGNE ILELIESIRV LSRDSRAGDE KAREQLLDKL
     ANISTENVLP VARAFSQFLN LTNIAEQYQT ISRHHQDESL GNRSLSALFA RLKAQGTPVE
     TVIKTVEKLS IELVLTAHPT EVTRRSLVHK HVEINKCLGQ LEHDDLTEAE QTKLKRRLMQ
     LIALAWHTNE IRAARPTPVD EAKWGMAIIE NSLWKAVPDF CRELNFQLEK HFDVQYEVAL
     SPVRFSSWMG GDRDGNPFVT AEITQKVLRM NRWKAAELFL NDVSDLVEEL SIVQCTPEFR
     EKYGDHIEPY RVVVKGLRSK LQKTLTYFGE LIEAKPTTVD PSEIITCDND LWEPLYDCYQ
     SLHACGMRII ANGSLLDCLR RIRCFGLGLS RLDIRQESSR HETAIAEITR YIGLGDYAQW
     TEDDKQAFLV RELSSRRPLV PTNWTPSPET QEILDTCKVV AQQPEGTISA YVISMAREAS
     DVLAVHLLLK EAGCNYTLPV APLFETLDDL DHSEKVMTDL FNIGWYRGVI NNYQMVMIGY
     SDSAKDAGML AASWAQYRAQ EALVNLAEKY HIELVLFHGR GGTVGRGGAP AHAALLSQPP
     RSLKSGLRVT EQGEMIRFKL GLPAVAVETL NLYASAILEA NLLPPPEPKQ KWRDIMDKGA
     AISCEIYRGV VRGEPDFVPY FRSATPEQEL GKLPLGSRPS KRNPNGGVES LRAIPWIFAW
     MQNRLMLPAW LGAGAALRQM IEQGEESTLK EMCNEWPFFS TRIGMLEMVF SKADLWLAEH
     YDQRLVAKEL HRLGKTLRAQ LSADIQTVLT LAHDGQLMAD LPWIAESIAL RNVYTDPLNL
     LQVELLQRLR SQGEVRDPQL EQALMITITG IAAGMRNTG