Y044_HAEIN
ID Y044_HAEIN Reviewed; 220 AA.
AC P44477;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1995, sequence version 1.
DT 03-AUG-2022, entry version 110.
DE RecName: Full=Uncharacterized protein HI_0044;
GN OrderedLocusNames=HI_0044;
OS Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC Pasteurellaceae; Haemophilus.
OX NCBI_TaxID=71421;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX PubMed=7542800; DOI=10.1126/science.7542800;
RA Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT Rd.";
RL Science 269:496-512(1995).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the BI1 family. {ECO:0000305}.
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DR EMBL; L42023; AAC21722.1; -; Genomic_DNA.
DR PIR; A64141; A64141.
DR RefSeq; NP_438217.1; NC_000907.1.
DR RefSeq; WP_005649826.1; NC_000907.1.
DR AlphaFoldDB; P44477; -.
DR SMR; P44477; -.
DR STRING; 71421.HI_0044; -.
DR EnsemblBacteria; AAC21722; AAC21722; HI_0044.
DR KEGG; hin:HI_0044; -.
DR PATRIC; fig|71421.8.peg.44; -.
DR eggNOG; COG0670; Bacteria.
DR HOGENOM; CLU_058671_2_1_6; -.
DR OMA; MGDVIGM; -.
DR PhylomeDB; P44477; -.
DR BioCyc; HINF71421:G1GJ1-44-MON; -.
DR Proteomes; UP000000579; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0043066; P:negative regulation of apoptotic process; IEA:InterPro.
DR InterPro; IPR006213; Bax_inhbtr1_CS.
DR InterPro; IPR006214; Bax_inhibitor_1-related.
DR PANTHER; PTHR23291; PTHR23291; 1.
DR Pfam; PF01027; Bax1-I; 1.
DR PROSITE; PS01243; BI1; 1.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..220
FT /note="Uncharacterized protein HI_0044"
FT /id="PRO_0000179104"
FT TRANSMEM 24..44
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 45..65
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 74..94
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 105..125
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 137..157
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 158..178
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 196..216
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 220 AA; 24246 MW; FDE34BE90F3F915C CRC64;
MQSRLIVDAQ KESLLSTHKV LRNTYFLLGL TMAFSAVVAF ISMSLNLPYP NIIVLLVGFY
GLLFLTNKLA DRPAGILAAF AFTGFMGYTI GPILNMYVAR GMEDLIMLAF AGTAIVFFAC
SAYVLTTKKD MSFLSSAMFA LFIVLLLGMV ASFFFQIPAL SVAISALFVV FSTMTILYET
SNIIHGGETN YIRATVNIYV SIYNLFLSLL RLLSIFSSDE