ID   Y044_MYCBO              Reviewed;         244 AA.
AC   P67738; A0A1R3XU51; P71700; X2BDV8;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   25-MAY-2022, entry version 99.
DE   RecName: Full=Uncharacterized HTH-type transcriptional regulator Mb0044c;
GN   OrderedLocusNames=BQ2027_MB0044C;
OS   Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=233413;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=12788972; DOI=10.1073/pnas.1130426100;
RA   Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M.,
RA   Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B.,
RA   Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J.,
RA   Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G.;
RT   "The complete genome sequence of Mycobacterium bovis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=28385856; DOI=10.1128/genomea.00157-17;
RA   Malone K.M., Farrell D., Stuber T.P., Schubert O.T., Aebersold R.,
RA   Robbe-Austerman S., Gordon S.V.;
RT   "Updated reference genome sequence and annotation of Mycobacterium bovis
RT   AF2122/97.";
RL   Genome Announc. 5:E00157-E00157(2017).
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DR   EMBL; LT708304; SIT98404.1; -; Genomic_DNA.
DR   RefSeq; NP_853713.1; NC_002945.3.
DR   RefSeq; WP_003899786.1; NC_002945.4.
DR   AlphaFoldDB; P67738; -.
DR   SMR; P67738; -.
DR   EnsemblBacteria; SIT98404; SIT98404; BQ2027_MB0044C.
DR   GeneID; 45424002; -.
DR   PATRIC; fig|233413.5.peg.50; -.
DR   OMA; HVQWIGR; -.
DR   Proteomes; UP000001419; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   CDD; cd07377; WHTH_GntR; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 1.20.120.530; -; 1.
DR   InterPro; IPR008920; TF_FadR/GntR_C.
DR   InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00392; GntR; 1.
DR   SMART; SM00345; HTH_GNTR; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS50949; HTH_GNTR; 1.
PE   4: Predicted;
KW   DNA-binding; Transcription; Transcription regulation.
FT   CHAIN           1..244
FT                   /note="Uncharacterized HTH-type transcriptional regulator
FT                   Mb0044c"
FT                   /id="PRO_0000050696"
FT   DOMAIN          7..74
FT                   /note="HTH gntR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00307"
FT   DNA_BIND        34..53
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00307"
SQ   SEQUENCE   244 AA;  27328 MW;  39BC96246E5F58BB CRC64;
     MPKKYGVKEK DQVVAHILNL LLTGKLRSGD RVDRNEIAHG LGVSRVPIQE ALVQLEHDGI
     VSTRYHRGAF IERFDVATIL EHHELDGLLN GIASARAAAN PTPRILGQLD AVMRSLRNSK
     ESRAFAECVW EYRRTVNDEY AGPRLHATIR ASQNLIPRVF WMTYQNSRDD VLPFYEEENA
     AIHRREPEAA RAACIGRSEL MAQTMLAELF RRRVLVPPEG ACPGPFGAPI PGFARSYQPS
     SPVP