ID   Y048_ARCFU              Reviewed;         413 AA.
AC   O30188;
DT   20-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   03-AUG-2022, entry version 81.
DE   RecName: Full=Uncharacterized protein AF_0048;
DE   Flags: Precursor;
GN   OrderedLocusNames=AF_0048;
OS   Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC
OS   100126 / VC-16).
OC   Archaea; Euryarchaeota; Archaeoglobi; Archaeoglobales; Archaeoglobaceae;
OC   Archaeoglobus.
OX   NCBI_TaxID=224325;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16;
RX   PubMed=9389475; DOI=10.1038/37052;
RA   Klenk H.-P., Clayton R.A., Tomb J.-F., White O., Nelson K.E., Ketchum K.A.,
RA   Dodson R.J., Gwinn M.L., Hickey E.K., Peterson J.D., Richardson D.L.,
RA   Kerlavage A.R., Graham D.E., Kyrpides N.C., Fleischmann R.D.,
RA   Quackenbush J., Lee N.H., Sutton G.G., Gill S.R., Kirkness E.F.,
RA   Dougherty B.A., McKenney K., Adams M.D., Loftus B.J., Peterson S.N.,
RA   Reich C.I., McNeil L.K., Badger J.H., Glodek A., Zhou L., Overbeek R.,
RA   Gocayne J.D., Weidman J.F., McDonald L.A., Utterback T.R., Cotton M.D.,
RA   Spriggs T., Artiach P., Kaine B.P., Sykes S.M., Sadow P.W., D'Andrea K.P.,
RA   Bowman C., Fujii C., Garland S.A., Mason T.M., Olsen G.J., Fraser C.M.,
RA   Smith H.O., Woese C.R., Venter J.C.;
RT   "The complete genome sequence of the hyperthermophilic, sulphate-reducing
RT   archaeon Archaeoglobus fulgidus.";
RL   Nature 390:364-370(1997).
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DR   EMBL; AE000782; AAB91184.1; -; Genomic_DNA.
DR   PIR; H69255; H69255.
DR   RefSeq; WP_010877562.1; NC_000917.1.
DR   AlphaFoldDB; O30188; -.
DR   STRING; 224325.AF_0048; -.
DR   EnsemblBacteria; AAB91184; AAB91184; AF_0048.
DR   GeneID; 1483257; -.
DR   KEGG; afu:AF_0048; -.
DR   eggNOG; arCOG07760; Archaea.
DR   HOGENOM; CLU_664988_0_0_2; -.
DR   OrthoDB; 32038at2157; -.
DR   Proteomes; UP000002199; Chromosome.
DR   GO; GO:0008234; F:cysteine-type peptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   Gene3D; 3.40.50.10390; -; 1.
DR   InterPro; IPR029030; Caspase-like_dom_sf.
DR   InterPro; IPR001769; Gingipain.
DR   InterPro; IPR029031; Gingipain_N_sf.
DR   Pfam; PF01364; Peptidase_C25; 1.
DR   SUPFAM; SSF52129; SSF52129; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Signal.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255"
FT   CHAIN           21..413
FT                   /note="Uncharacterized protein AF_0048"
FT                   /id="PRO_0000013635"
SQ   SEQUENCE   413 AA;  45964 MW;  512EB4A93A467864 CRC64;
     MRVIIVIMMV VFVVVGTSSG QEIILTSEKL INSAYQLQEI HEKVGIQSDI VTVEQIWDSY
     SPVEDPLVSG YSTEQVYDSY NYTLALKIIS FLRTVNASYV TILGDADIVP PSYYAKLIFY
     EPFPTDFFYA SPDYDLKPDF AVGRIPAGSE DEAEKVLGKI NDWLSDIGSG NYVNAALIGM
     RIYAAPYSIE RETIDDYEVW QGETAVKLLE DLGFTETFNT TIALQSDEEW TSVKQTFDEA
     LSGGYGVVFH VGHGIPYALD SDDGGMYTTR YMNMLDKRRP LLPVVLSSGC SAAAFDEEIR
     DIYLPNWAPG LWSEFLLTND AGGIAFVGFT GTTGSDYQFS ESDGFVEVAG VKHADNILIK
     TLKNLPGNRL GDAFKAALEE VKSEENIKLN PSTEVEEWKL RVYLEAETKF LET