ID   Y049_PYRAE              Reviewed;         371 AA.
AC   Q8ZZW3;
DT   13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2005, sequence version 2.
DT   25-MAY-2022, entry version 87.
DE   RecName: Full=Uncharacterized serpin-like protein PAE0049;
GN   OrderedLocusNames=PAE0049;
OS   Pyrobaculum aerophilum (strain ATCC 51768 / DSM 7523 / JCM 9630 / CIP
OS   104966 / NBRC 100827 / IM2).
OC   Archaea; Crenarchaeota; Thermoprotei; Thermoproteales; Thermoproteaceae;
OC   Pyrobaculum.
OX   NCBI_TaxID=178306;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51768 / DSM 7523 / JCM 9630 / CIP 104966 / NBRC 100827 / IM2;
RX   PubMed=11792869; DOI=10.1073/pnas.241636498;
RA   Fitz-Gibbon S.T., Ladner H., Kim U.-J., Stetter K.O., Simon M.I.,
RA   Miller J.H.;
RT   "Genome sequence of the hyperthermophilic crenarchaeon Pyrobaculum
RT   aerophilum.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:984-989(2002).
CC   -!- SIMILARITY: Belongs to the serpin family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAL62526.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AE009441; AAL62526.1; ALT_INIT; Genomic_DNA.
DR   AlphaFoldDB; Q8ZZW3; -.
DR   SMR; Q8ZZW3; -.
DR   STRING; 178306.PAE0049; -.
DR   MEROPS; I04.079; -.
DR   EnsemblBacteria; AAL62526; AAL62526; PAE0049.
DR   KEGG; pai:PAE0049; -.
DR   PATRIC; fig|178306.9.peg.35; -.
DR   eggNOG; arCOG04933; Archaea.
DR   HOGENOM; CLU_023330_0_4_2; -.
DR   InParanoid; Q8ZZW3; -.
DR   OMA; KDVWRGL; -.
DR   Proteomes; UP000002439; Chromosome.
DR   GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR   Gene3D; 2.30.39.10; -; 1.
DR   Gene3D; 3.30.497.10; -; 1.
DR   InterPro; IPR023795; Serpin_CS.
DR   InterPro; IPR023796; Serpin_dom.
DR   InterPro; IPR000215; Serpin_fam.
DR   InterPro; IPR036186; Serpin_sf.
DR   InterPro; IPR042178; Serpin_sf_1.
DR   InterPro; IPR042185; Serpin_sf_2.
DR   PANTHER; PTHR11461; PTHR11461; 1.
DR   Pfam; PF00079; Serpin; 1.
DR   SMART; SM00093; SERPIN; 1.
DR   SUPFAM; SSF56574; SSF56574; 1.
DR   PROSITE; PS00284; SERPIN; 1.
PE   3: Inferred from homology;
KW   Protease inhibitor; Reference proteome; Serine protease inhibitor.
FT   CHAIN           1..371
FT                   /note="Uncharacterized serpin-like protein PAE0049"
FT                   /id="PRO_0000094164"
FT   SITE            328..329
FT                   /note="Reactive bond"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   371 AA;  41029 MW;  DD31398A30D52C60 CRC64;
     MRPLPSQLPI PLSPEGYGRF AVEFYKRVAV GILGENLVLS PYSVYKAFAM AYAGASGATR
     EELKAVFGFG EDPCVLPAAS RGVEEALSAW LQTDFPFKPN YLNKLRCIGA EAKYVDFERD
     YKSAIAAINK WAEEKTRGLI KDLVPADYPE GWDVRAVLVS ALYFKGNWWP DRFQRVGKRE
     FKGAGPADFI ALDLSSCGDP SLRGRASSDL TVVELPFNNT EVALYIIMPR DLPSFVKELT
     YEKLREIIST LPDQVIRVEM PLFKAEFKGS VKQALREMGV VRAFETADFT EMAYRRLYID
     DVFHGAYLNA DENGVVAAAA TAVVFKPVCA KGGGVEVVVD KPFLFVLADR TSGVIYFIGH
     VVNPSPGFTP T