ID   Y051_MYCTU              Reviewed;         640 AA.
AC   P9WIW3; L0T497; O53628; Q10880;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 31.
DE   RecName: Full=Uncharacterized protein Rv0083;
GN   OrderedLocusNames=Rv0083; ORFNames=MTCY251.01, MTV030.27;
OS   Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=9634230; DOI=10.1038/31159;
RA   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA   Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA   Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA   Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA   Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA   Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA   Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA   Barrell B.G.;
RT   "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT   genome sequence.";
RL   Nature 393:537-544(1998).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the complex I subunit 4 family. {ECO:0000305}.
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DR   EMBL; AL123456; CCP42808.1; -; Genomic_DNA.
DR   PIR; D70850; D70850.
DR   RefSeq; NP_214597.1; NC_000962.3.
DR   RefSeq; WP_003907280.1; NZ_NVQJ01000005.1.
DR   AlphaFoldDB; P9WIW3; -.
DR   SMR; P9WIW3; -.
DR   STRING; 83332.Rv0083; -.
DR   PaxDb; P9WIW3; -.
DR   GeneID; 886965; -.
DR   KEGG; mtu:Rv0083; -.
DR   TubercuList; Rv0083; -.
DR   eggNOG; COG0651; Bacteria.
DR   OMA; AMCFVKV; -.
DR   PhylomeDB; P9WIW3; -.
DR   Proteomes; UP000001584; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR   GO; GO:0042773; P:ATP synthesis coupled electron transport; IEA:InterPro.
DR   InterPro; IPR003918; NADH_UbQ_OxRdtase.
DR   InterPro; IPR001750; ND/Mrp_mem.
DR   Pfam; PF00361; Proton_antipo_M; 1.
DR   PRINTS; PR01437; NUOXDRDTASE4.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Oxidoreductase; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..640
FT                   /note="Uncharacterized protein Rv0083"
FT                   /id="PRO_0000118049"
FT   TRANSMEM        8..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        52..72
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        90..110
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        136..156
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        179..199
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        208..228
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        241..261
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        277..297
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        298..318
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        352..372
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        391..411
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        446..466
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        497..517
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        619..639
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   640 AA;  65628 MW;  6254C289DBD108A8 CRC64;
     MTAAPTAGGV VTSGVGVAGV GVGLLGMFGP VRVVHVGWLL PLSGVHIELD RLGGFFMALT
     GAVAAPVGCY LIGYVRREHL GRVPMAVVPL FVAAMLLVPA AGSVTTFLLA WELMAIASLI
     LVLSEHARPQ VRSAGLWYAV MTQLGFIAIL VGLVVLAAAG GSDRFAGLGA VCDGVRAAVF
     MLTLVGFGSK AGLVPLHAWL PRAHPEAPSP VSALMSAAMV NLGIYGIVRF DLQLLGPGPR
     WWGLALLAVG GTSALYGVLQ ASVAADLKRL LAYSTTENMG LITLALGAAT LFADTGAYGP
     ASIAAAAAML HMIAHAAFKS LAFMAAGSVL AATGLRDLDL LGGLARRMPA TTVFFGVAAL
     GACGLPLGAG FVSEWLLVQS LIHAAPGHDP IVALTTPLAV GVVALATGLS VAAMTKAFGI
     GFLARPRSTQ AEAAREAPAS MRAGMAIAAG ACLVLAVAPL LVAPMVRRAA ATLPAAQAVK
     FTGLGAVVRL PAMSGSIAPG VIAAAVLAAA LAVAVLARWR FRRRPAPARL PLWACGAADL
     TVRMQYTATS FAEPLQRVFG DVLRPDTDIE VTHTAESRYM AERITYRTAV ADAIEQRLYT
     PVVGAVAAMA ELLRRAHTGS VHRYLAYGAL GVLIVLVVAR