ID   CAPP_CAUVC              Reviewed;         909 AA.
AC   Q9A871;
DT   08-NOV-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   03-AUG-2022, entry version 103.
DE   RecName: Full=Phosphoenolpyruvate carboxylase {ECO:0000255|HAMAP-Rule:MF_00595};
DE            Short=PEPC {ECO:0000255|HAMAP-Rule:MF_00595};
DE            Short=PEPCase {ECO:0000255|HAMAP-Rule:MF_00595};
DE            EC=4.1.1.31 {ECO:0000255|HAMAP-Rule:MF_00595};
GN   Name=ppc {ECO:0000255|HAMAP-Rule:MF_00595}; OrderedLocusNames=CC_1493;
OS   Caulobacter vibrioides (strain ATCC 19089 / CB15) (Caulobacter crescentus).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Caulobacterales;
OC   Caulobacteraceae; Caulobacter.
OX   NCBI_TaxID=190650;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 19089 / CB15;
RX   PubMed=11259647; DOI=10.1073/pnas.061029298;
RA   Nierman W.C., Feldblyum T.V., Laub M.T., Paulsen I.T., Nelson K.E.,
RA   Eisen J.A., Heidelberg J.F., Alley M.R.K., Ohta N., Maddock J.R.,
RA   Potocka I., Nelson W.C., Newton A., Stephens C., Phadke N.D., Ely B.,
RA   DeBoy R.T., Dodson R.J., Durkin A.S., Gwinn M.L., Haft D.H., Kolonay J.F.,
RA   Smit J., Craven M.B., Khouri H.M., Shetty J., Berry K.J., Utterback T.R.,
RA   Tran K., Wolf A.M., Vamathevan J.J., Ermolaeva M.D., White O.,
RA   Salzberg S.L., Venter J.C., Shapiro L., Fraser C.M.;
RT   "Complete genome sequence of Caulobacter crescentus.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:4136-4141(2001).
CC   -!- FUNCTION: Forms oxaloacetate, a four-carbon dicarboxylic acid source
CC       for the tricarboxylic acid cycle. {ECO:0000255|HAMAP-Rule:MF_00595}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=oxaloacetate + phosphate = hydrogencarbonate +
CC         phosphoenolpyruvate; Xref=Rhea:RHEA:28370, ChEBI:CHEBI:16452,
CC         ChEBI:CHEBI:17544, ChEBI:CHEBI:43474, ChEBI:CHEBI:58702; EC=4.1.1.31;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00595};
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00595};
CC   -!- SIMILARITY: Belongs to the PEPCase type 1 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00595}.
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DR   EMBL; AE005673; AAK23472.1; -; Genomic_DNA.
DR   PIR; D87434; D87434.
DR   RefSeq; NP_420304.1; NC_002696.2.
DR   RefSeq; WP_010919367.1; NC_002696.2.
DR   AlphaFoldDB; Q9A871; -.
DR   SMR; Q9A871; -.
DR   STRING; 190650.CC_1493; -.
DR   EnsemblBacteria; AAK23472; AAK23472; CC_1493.
DR   KEGG; ccr:CC_1493; -.
DR   PATRIC; fig|190650.5.peg.1520; -.
DR   eggNOG; COG2352; Bacteria.
DR   HOGENOM; CLU_006557_2_0_5; -.
DR   OMA; PWVFGWT; -.
DR   BioCyc; CAULO:CC1493-MON; -.
DR   Proteomes; UP000001816; Chromosome.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0008964; F:phosphoenolpyruvate carboxylase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0015977; P:carbon fixation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006107; P:oxaloacetate metabolic process; IEA:UniProtKB-UniRule.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR   HAMAP; MF_00595; PEPcase_type1; 1.
DR   InterPro; IPR021135; PEP_COase.
DR   InterPro; IPR022805; PEP_COase_bac/pln-type.
DR   InterPro; IPR018129; PEP_COase_Lys_AS.
DR   InterPro; IPR033129; PEPCASE_His_AS.
DR   InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR   PANTHER; PTHR30523; PTHR30523; 1.
DR   Pfam; PF00311; PEPcase; 1.
DR   PRINTS; PR00150; PEPCARBXLASE.
DR   SUPFAM; SSF51621; SSF51621; 1.
DR   PROSITE; PS00781; PEPCASE_1; 1.
DR   PROSITE; PS00393; PEPCASE_2; 1.
PE   3: Inferred from homology;
KW   Carbon dioxide fixation; Lyase; Magnesium; Reference proteome.
FT   CHAIN           1..909
FT                   /note="Phosphoenolpyruvate carboxylase"
FT                   /id="PRO_0000166586"
FT   ACT_SITE        151
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00595"
FT   ACT_SITE        578
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00595"
SQ   SEQUENCE   909 AA;  98874 MW;  905B101672477012 CRC64;
     MRNPALSIDV DRPTSRHVRQ NAHLLSDLLI EAITYLEGEE KAELVAKARK AASREDVVNG
     DAPLLDHLFS DLTTEQAVFL ARAFASHSLL ANIGEDVAGR RRHAEADAQP GDERPRTLID
     AVKALKAAGK SDAELAKIFA AMNVVPVLTA HPTEVRRRSM VDRETEISRL MALRRHHLPP
     DLEAEIRESL FREIALMWRT RLYRPERITV KDEIRNALSI VRTSILPAII DLYGDWTGKI
     GQHGQLAPLL KMGSWLGGDR DGHPGVNGQT LKLALSSQSR VILDWYAGEV RKLWSNLAVS
     TAYTPVSDEL LALAAQAKDP SVHRIDEPYR LALELIFDRL TAVSQKLTGA PVAFASGVTS
     VEPYAHPDAF VADLSVIIDS LERNGGERLV GSALRTLVEV AKACGFHLMS LDLRQNADVH
     ERTLDELFRR AGTGVEYLKL DEDARCKVLI DELSHQRPLV SPFTAYGEET SKELATMEAA
     AQAVRDYGHG CLGAYIISKS ATLSDMLEPL VLLKQVGLVW GGAAPRASVK VAPLFETIGD
     LENGPAVLRQ WLELPLSRTI LGDRPVQEIM LGYSDSNKDG GYVASRRGVA TGASALAHEA
     DRMGVGLQLF HGRGGSVGRG GGPAAEAVLA QPAGTVQGRI RMTEQGEMIA RRFGDQPTAR
     RNLDGLAAAV LMASERPIPK RDPKVEGAMT ALAQSSFEGY RALVYDDAAF EDFFWSVTPI
     SEIVGLNIGS RPASRTASRK IEDLRAIPWV FSWSQARFML PGWYGFASGV ERAGLSVEQL
     RDLAGNFDFF ASLLSNMELA LAQSQMGIAA RYVALSPDKA NAERIFATIR REHEAATGLA
     LAIRGGAALL DNQPDLAESV ALASRSVDPL NHLQLELLSR RRAGDIDEEL RLAIQLTVAG
     IAAGLRNTG