ID   Y0555_DICDI             Reviewed;         508 AA.
AC   Q54FW9;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 96.
DE   RecName: Full=WD repeat-containing protein DDB_G0290555;
GN   ORFNames=DDB_G0290555;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
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DR   EMBL; AAFI02000164; EAL62138.1; -; Genomic_DNA.
DR   RefSeq; XP_635648.1; XM_630556.1.
DR   AlphaFoldDB; Q54FW9; -.
DR   SMR; Q54FW9; -.
DR   STRING; 44689.DDB0304570; -.
DR   PaxDb; Q54FW9; -.
DR   EnsemblProtists; EAL62138; EAL62138; DDB_G0290555.
DR   GeneID; 8627720; -.
DR   KEGG; ddi:DDB_G0290555; -.
DR   dictyBase; DDB_G0290555; -.
DR   eggNOG; KOG3881; Eukaryota.
DR   HOGENOM; CLU_536864_0_0_1; -.
DR   InParanoid; Q54FW9; -.
DR   OMA; TDNMDSD; -.
DR   PhylomeDB; Q54FW9; -.
DR   PRO; PR:Q54FW9; -.
DR   Proteomes; UP000002195; Chromosome 5.
DR   GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR   GO; GO:0030687; C:preribosome, large subunit precursor; IBA:GO_Central.
DR   GO; GO:0042273; P:ribosomal large subunit biogenesis; IBA:GO_Central.
DR   Gene3D; 2.130.10.10; -; 1.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   InterPro; IPR037379; WDR74/Nsa1.
DR   PANTHER; PTHR16038; PTHR16038; 1.
DR   SMART; SM00320; WD40; 2.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   4: Predicted;
KW   Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..508
FT                   /note="WD repeat-containing protein DDB_G0290555"
FT                   /id="PRO_0000384447"
FT   REPEAT          32..74
FT                   /note="WD 1"
FT   REPEAT          159..198
FT                   /note="WD 2"
FT   REPEAT          252..292
FT                   /note="WD 3"
FT   REPEAT          295..334
FT                   /note="WD 4"
FT   REGION          368..508
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        368..399
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        400..430
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        432..446
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        466..496
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   508 AA;  57151 MW;  C812B0F6F174A6C4 CRC64;
     MDVLVGCSTG INKIYNIHKK TPTGLYGALN TTSELNVMTF GWNSVENNED YVFYGYSNGI
     LKYWNQKEKQ LIGEIDYGQS IKAIHPLNND KLLVALENGL VDVKTLTAPI TTQLAPMNLP
     TLNKKKSPAA AAAASTVGKN NKSKQVIVEP VNTQSFSLNV ATNLSGFAMN PSNDKFAFGG
     KDVNLTIWDL EKQVKTYSAK FKHDFLNLQE PVSINVVKYM NDDKILIGSD FRIKAYDLRS
     KTNRSSFLDV SFSKHPIQSI QYTNQKEHYF YASDSIGKVF CYDVRTSRQV GSFKDSAGSV
     KDIAIHPTLP LLATVGLDRH LRVYNLDNRK MLHKIFLKQR LSCVLFSKEE PTNEIAQEEE
     EIWKNLEENK NRINNDDNDD NNEGNDKKKS ISIKVTDNMD SDDDIEDGDD NDVEFPMEAD
     SDDSDFDLGN SDDDNISVKK ENKGDSDDSD DDSDEDEKPK RKTPAKSNLR NNNNNNNKGK
     NNKGKNNSST KKTSQVLKKK FAGLKKRK