ID   Y0569_BRAHW             Reviewed;         368 AA.
AC   C0QYX7; C4MGG2;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-MAY-2009, sequence version 1.
DT   25-MAY-2022, entry version 60.
DE   RecName: Full=Uncharacterized protein BHWA1_00569;
DE   AltName: Full=H-34;
GN   OrderedLocusNames=BHWA1_00569;
OS   Brachyspira hyodysenteriae (strain ATCC 49526 / WA1).
OC   Bacteria; Spirochaetes; Brachyspirales; Brachyspiraceae; Brachyspira.
OX   NCBI_TaxID=565034;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND BIOTECHNOLOGY.
RX   PubMed=19179021; DOI=10.1016/j.vetmic.2008.12.018;
RA   Song Y., La T., Phillips N.D., Bellgard M.I., Hampson D.J.;
RT   "A reverse vaccinology approach to swine dysentery vaccine development.";
RL   Vet. Microbiol. 137:111-119(2009).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 49526 / WA1;
RX   PubMed=19262690; DOI=10.1371/journal.pone.0004641;
RA   Bellgard M.I., Wanchanthuek P., La T., Ryan K., Moolhuijzen P.,
RA   Albertyn Z., Shaban B., Motro Y., Dunn D.S., Schibeci D., Hunter A.,
RA   Barrero R., Phillips N.D., Hampson D.J.;
RT   "Genome sequence of the pathogenic intestinal spirochete Brachyspira
RT   hyodysenteriae reveals adaptations to its lifestyle in the porcine large
RT   intestine.";
RL   PLoS ONE 4:E4641-E4641(2009).
CC   -!- FUNCTION: Might be involved in sporulation.
CC   -!- BIOTECHNOLOGY: Has shown promise in a 4-component vaccine with
CC       BHWA1_00430 (AC C0QY54), SecA (AC C0QZS7) and FlaAL (AC C0QWY9).
CC       {ECO:0000269|PubMed:19179021}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ACD74836.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; EU555166; ACD74836.1; ALT_INIT; Genomic_DNA.
DR   EMBL; CP001357; ACN83065.1; -; Genomic_DNA.
DR   AlphaFoldDB; C0QYX7; -.
DR   SMR; C0QYX7; -.
DR   STRING; 565034.BHWA1_00569; -.
DR   EnsemblBacteria; ACN83065; ACN83065; BHWA1_00569.
DR   KEGG; bhy:BHWA1_00569; -.
DR   eggNOG; COG2385; Bacteria.
DR   HOGENOM; CLU_021203_3_3_12; -.
DR   OMA; LCQWGAK; -.
DR   Proteomes; UP000001803; Chromosome.
DR   GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:InterPro.
DR   InterPro; IPR013486; SpoIID/LytB.
DR   InterPro; IPR013693; SpoIID/LytB_N.
DR   PANTHER; PTHR30032:SF4; PTHR30032:SF4; 1.
DR   Pfam; PF08486; SpoIID; 1.
DR   TIGRFAMs; TIGR02669; SpoIID_LytB; 1.
PE   1: Evidence at protein level;
FT   CHAIN           1..368
FT                   /note="Uncharacterized protein BHWA1_00569"
FT                   /id="PRO_0000380705"
SQ   SEQUENCE   368 AA;  41325 MW;  CBA171A209391765 CRC64;
     MNSIYAFANQ NIIRVQLTDV KAPYTINIKG PYKAYNYKYE SEIISALTNE TVMVVENRLG
     LKVNEVGVYK EGIVFETQDG FTLNGIEYYG SLMFIPYNDT MIVVNELNIE DYVKGVLPHE
     MSPDWPMEAL KAQAVAARTY AMYHILKNAN KLPFDVDNTT KYQVYNGKEK MNWSVEQAVD
     RTRYEIAVYK GKVIATYFSA LCGGHTDSAE NVFGVAVPYL GGVACPYCNA QIKPWTNALS
     YNELNNDLAN YSVHATEKSS IGISTDPKSG KATNIKIDNN DITSRDFRTT LSPRLVPSLN
     FTIKKVDNGI IITGKGSGHG VGMCQWGAYG MAQVKKDYKE ILKFYYNGVD IVDYNRVNKE
     FEPDVWGN