ID   Y0585_STAHJ             Reviewed;         231 AA.
AC   Q4L8Y1;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   02-AUG-2005, sequence version 1.
DT   03-AUG-2022, entry version 118.
DE   RecName: Full=Uncharacterized oxidoreductase SH0585;
DE            EC=1.-.-.-;
GN   OrderedLocusNames=SH0585;
OS   Staphylococcus haemolyticus (strain JCSC1435).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=279808;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCSC1435;
RX   PubMed=16237012; DOI=10.1128/jb.187.21.7292-7308.2005;
RA   Takeuchi F., Watanabe S., Baba T., Yuzawa H., Ito T., Morimoto Y.,
RA   Kuroda M., Cui L., Takahashi M., Ankai A., Baba S., Fukui S., Lee J.C.,
RA   Hiramatsu K.;
RT   "Whole-genome sequencing of Staphylococcus haemolyticus uncovers the
RT   extreme plasticity of its genome and the evolution of human-colonizing
RT   staphylococcal species.";
RL   J. Bacteriol. 187:7292-7308(2005).
CC   -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC       family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AP006716; BAE03894.1; -; Genomic_DNA.
DR   RefSeq; WP_011274910.1; NC_007168.1.
DR   AlphaFoldDB; Q4L8Y1; -.
DR   SMR; Q4L8Y1; -.
DR   STRING; 279808.SH0585; -.
DR   EnsemblBacteria; BAE03894; BAE03894; SH0585.
DR   KEGG; sha:SH0585; -.
DR   eggNOG; COG4221; Bacteria.
DR   HOGENOM; CLU_010194_2_1_9; -.
DR   OMA; ITGGRNW; -.
DR   OrthoDB; 1261526at2; -.
DR   Proteomes; UP000000543; Chromosome.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR002347; SDR_fam.
DR   Pfam; PF00106; adh_short; 1.
DR   PRINTS; PR00081; GDHRDH.
DR   PRINTS; PR00080; SDRFAMILY.
DR   SUPFAM; SSF51735; SSF51735; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase.
FT   CHAIN           1..231
FT                   /note="Uncharacterized oxidoreductase SH0585"
FT                   /id="PRO_0000300480"
FT   ACT_SITE        153
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000250"
FT   BINDING         10..34
FT                   /ligand="NADP(+)"
FT                   /ligand_id="ChEBI:CHEBI:58349"
FT                   /evidence="ECO:0000250"
FT   BINDING         140
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   231 AA;  24679 MW;  47803F953885860C CRC64;
     MTELNGRVAI ITGASSGIGA ATAKALEKQG VKVVLAGRSH DKLNTLAKDM NEDNIHIVPT
     DVTNQVEVDA LVAKVIDVFG HVDIFVNCAG VMRSSKITDY QVESWDSMVD TNIKGLLYSL
     NAILPKFEAQ GSGHVVNLAS ISANEVSKES ALYSATKSAV LMIFNGLEKE LAKTGIKTTS
     ILPGMVDTPM TERSDFGGRK KLDPENIADA IIYALTQPAH VNVNEVTVRP V