ID   Y0656_EMENI             Reviewed;         286 AA.
AC   Q5BFM4; C8VRZ7;
DT   10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT   26-APR-2005, sequence version 1.
DT   03-AUG-2022, entry version 80.
DE   RecName: Full=Uncharacterized methyltransferase AN0656;
DE            EC=2.1.1.-;
GN   ORFNames=AN0656;
OS   Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 /
OS   M139) (Aspergillus nidulans).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Nidulantes.
OX   NCBI_TaxID=227321;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX   PubMed=16372000; DOI=10.1038/nature04341;
RA   Galagan J.E., Calvo S.E., Cuomo C., Ma L.-J., Wortman J.R., Batzoglou S.,
RA   Lee S.-I., Bastuerkmen M., Spevak C.C., Clutterbuck J., Kapitonov V.,
RA   Jurka J., Scazzocchio C., Farman M.L., Butler J., Purcell S., Harris S.,
RA   Braus G.H., Draht O., Busch S., D'Enfert C., Bouchier C., Goldman G.H.,
RA   Bell-Pedersen D., Griffiths-Jones S., Doonan J.H., Yu J., Vienken K.,
RA   Pain A., Freitag M., Selker E.U., Archer D.B., Penalva M.A., Oakley B.R.,
RA   Momany M., Tanaka T., Kumagai T., Asai K., Machida M., Nierman W.C.,
RA   Denning D.W., Caddick M.X., Hynes M., Paoletti M., Fischer R., Miller B.L.,
RA   Dyer P.S., Sachs M.S., Osmani S.A., Birren B.W.;
RT   "Sequencing of Aspergillus nidulans and comparative analysis with A.
RT   fumigatus and A. oryzae.";
RL   Nature 438:1105-1115(2005).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX   PubMed=19146970; DOI=10.1016/j.fgb.2008.12.003;
RA   Wortman J.R., Gilsenan J.M., Joardar V., Deegan J., Clutterbuck J.,
RA   Andersen M.R., Archer D., Bencina M., Braus G., Coutinho P., von Dohren H.,
RA   Doonan J., Driessen A.J., Durek P., Espeso E., Fekete E., Flipphi M.,
RA   Estrada C.G., Geysens S., Goldman G., de Groot P.W., Hansen K.,
RA   Harris S.D., Heinekamp T., Helmstaedt K., Henrissat B., Hofmann G.,
RA   Homan T., Horio T., Horiuchi H., James S., Jones M., Karaffa L.,
RA   Karanyi Z., Kato M., Keller N., Kelly D.E., Kiel J.A., Kim J.M.,
RA   van der Klei I.J., Klis F.M., Kovalchuk A., Krasevec N., Kubicek C.P.,
RA   Liu B., Maccabe A., Meyer V., Mirabito P., Miskei M., Mos M., Mullins J.,
RA   Nelson D.R., Nielsen J., Oakley B.R., Osmani S.A., Pakula T., Paszewski A.,
RA   Paulsen I., Pilsyk S., Pocsi I., Punt P.J., Ram A.F., Ren Q., Robellet X.,
RA   Robson G., Seiboth B., van Solingen P., Specht T., Sun J.,
RA   Taheri-Talesh N., Takeshita N., Ussery D., vanKuyk P.A., Visser H.,
RA   van de Vondervoort P.J., de Vries R.P., Walton J., Xiang X., Xiong Y.,
RA   Zeng A.P., Brandt B.W., Cornell M.J., van den Hondel C.A., Visser J.,
RA   Oliver S.G., Turner G.;
RT   "The 2008 update of the Aspergillus nidulans genome annotation: a community
RT   effort.";
RL   Fungal Genet. Biol. 46:S2-13(2009).
RN   [3]
RP   INDUCTION, AND IDENTIFICATION BY MASS SPECTROMETRY.
RX   PubMed=17258477; DOI=10.1016/j.fgb.2006.12.001;
RA   Kim Y., Nandakumar M.P., Marten M.R.;
RT   "Proteome map of Aspergillus nidulans during osmoadaptation.";
RL   Fungal Genet. Biol. 44:886-895(2007).
CC   -!- FUNCTION: Involved in osmoadaptation.
CC   -!- INDUCTION: Down-regulated when grown with elevated levels of potassium
CC       chloride. {ECO:0000269|PubMed:17258477}.
CC   -!- SIMILARITY: Belongs to the methyltransferase superfamily.
CC       {ECO:0000305}.
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DR   EMBL; AACD01000010; EAA65432.1; -; Genomic_DNA.
DR   EMBL; BN001308; CBF89047.1; -; Genomic_DNA.
DR   RefSeq; XP_658260.1; XM_653168.1.
DR   AlphaFoldDB; Q5BFM4; -.
DR   SMR; Q5BFM4; -.
DR   EnsemblFungi; CBF89047; CBF89047; ANIA_00656.
DR   EnsemblFungi; EAA65432; EAA65432; AN0656.2.
DR   GeneID; 2876428; -.
DR   KEGG; ani:AN0656.2; -.
DR   VEuPathDB; FungiDB:AN0656; -.
DR   eggNOG; ENOG502S3GB; Eukaryota.
DR   HOGENOM; CLU_072385_0_0_1; -.
DR   InParanoid; Q5BFM4; -.
DR   OMA; TNMHSEM; -.
DR   OrthoDB; 785883at2759; -.
DR   Proteomes; UP000000560; Chromosome VIII.
DR   Proteomes; UP000005890; Unassembled WGS sequence.
DR   GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR   GO; GO:0004395; F:hexaprenyldihydroxybenzoate methyltransferase activity; IBA:GO_Central.
DR   GO; GO:0008168; F:methyltransferase activity; IBA:GO_Central.
DR   GO; GO:0071470; P:cellular response to osmotic stress; IEP:AspGD.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   GO; GO:0006744; P:ubiquinone biosynthetic process; IBA:GO_Central.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR041698; Methyltransf_25.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   Pfam; PF13649; Methyltransf_25; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
PE   1: Evidence at protein level;
KW   Methyltransferase; Reference proteome; Stress response; Transferase.
FT   CHAIN           1..286
FT                   /note="Uncharacterized methyltransferase AN0656"
FT                   /id="PRO_0000363401"
SQ   SEQUENCE   286 AA;  31032 MW;  F5E7AC6611B35F12 CRC64;
     MTNQTIQEAL GHGQGNDLGN SDGHRIEYVE TIEAYNKWAE VYDTDGNFLQ ALDTFEMKDL
     LPRFLCLVQT QTNGKSNMTP GEQVLKLVDL GCGTGRNTLQ LAKSAPKEAQ IIGLDASPGM
     LEVAEGNLKA QGVMGTVDER RVVLGVYDLL SPRPESLPVS LRGEARASGA ISTLVLEHIP
     LDKFFEGAAR LIRPGGYLLV TNMHAEMGAI SQAGFVDVTS GKKIRPTSYA HEVGNVIAAA
     ERAGFEIVPL NGAEKVRERR VNEEMVALLG SRARKWVNVV VWFGLS