ID   Y066_METJA              Reviewed;         480 AA.
AC   Q60377;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 1.
DT   25-MAY-2022, entry version 98.
DE   RecName: Full=Uncharacterized protein MJ0066;
GN   OrderedLocusNames=MJ0066;
OS   Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM
OS   10045 / NBRC 100440) (Methanococcus jannaschii).
OC   Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC   Methanocaldococcaceae; Methanocaldococcus.
OX   NCBI_TaxID=243232;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX   PubMed=8688087; DOI=10.1126/science.273.5278.1058;
RA   Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G.,
RA   Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R.,
RA   Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R.,
RA   Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L.,
RA   Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R.,
RA   Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D.,
RA   Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P.,
RA   Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
RT   "Complete genome sequence of the methanogenic archaeon, Methanococcus
RT   jannaschii.";
RL   Science 273:1058-1073(1996).
CC   -!- SIMILARITY: In the C-terminal section; belongs to the PAPS reductase
CC       family. {ECO:0000305}.
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DR   EMBL; L77117; AAB98046.1; -; Genomic_DNA.
DR   PIR; B64308; B64308.
DR   AlphaFoldDB; Q60377; -.
DR   SMR; Q60377; -.
DR   STRING; 243232.MJ_0066; -.
DR   EnsemblBacteria; AAB98046; AAB98046; MJ_0066.
DR   KEGG; mja:MJ_0066; -.
DR   eggNOG; arCOG00073; Archaea.
DR   HOGENOM; CLU_026622_0_0_2; -.
DR   InParanoid; Q60377; -.
DR   OMA; RWCCKVT; -.
DR   PhylomeDB; Q60377; -.
DR   Proteomes; UP000000805; Chromosome.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   CDD; cd01713; PAPS_reductase; 1.
DR   Gene3D; 2.30.130.10; -; 1.
DR   Gene3D; 3.40.50.620; -; 1.
DR   InterPro; IPR002500; PAPS_reduct.
DR   InterPro; IPR002478; PUA.
DR   InterPro; IPR015947; PUA-like_sf.
DR   InterPro; IPR036974; PUA_sf.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   InterPro; IPR004521; Uncharacterised_CHP00451.
DR   Pfam; PF01507; PAPS_reduct; 1.
DR   Pfam; PF01472; PUA; 1.
DR   SMART; SM00359; PUA; 1.
DR   SUPFAM; SSF88697; SSF88697; 1.
DR   TIGRFAMs; TIGR00451; unchar_dom_2; 1.
DR   PROSITE; PS50890; PUA; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase; Reference proteome.
FT   CHAIN           1..480
FT                   /note="Uncharacterized protein MJ0066"
FT                   /id="PRO_0000100693"
FT   DOMAIN          131..207
FT                   /note="PUA"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00161"
SQ   SEQUENCE   480 AA;  56371 MW;  8076C1D9A79B53D3 CRC64;
     MWEVIIMKTY IGKIHLKWCK NCNVPLLGRV CEVCGSKAEE VKLTPPGDPR LGFQYDMDFI
     NKILEEEFGA KNVLNGKIIL LNKIPGNEEA YEIIVDGEVK YLIYFDEDKE KWKVKLKLNG
     AKDLMEKGAY KKIIKIKNDV VEFLKNRKGS VLRPGIVEFT DDIEEKDDVI IVDENDRVVG
     VGLAVVSSED IKNMEKGKVV KVRFFIKDNE DYKPGKIYDN LEEAFDLMVR ANEGVIDNYE
     RNAIGFIKNT YEKIKKPVMV AFSGGKDSLV TLILTLKALG KDIDVVFIDT GLEFEETLKN
     VEDVERHYGI KIIRLRGENF WEKVKEYGIP ARDYRWCSEI CKLEPLKKFI EENYEDDVLS
     FVGIRKYESF NRATKKRIHR NTYIKKQINA LPIFHWSSLH VWIYLLREKA PYNKLYEKGF
     DRIGCFMCPA MEMGEMNKIK REFPKLWEKW ENVLREYAEK HNLGEGWIKK GLWRWKHKRQ