ID   Y072_MYCTO              Reviewed;         349 AA.
AC   P9WG16; L0T2H8; O53617; Q7DAI3;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 38.
DE   RecName: Full=Uncharacterized ABC transporter permease MT0078;
GN   OrderedLocusNames=MT0078;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- FUNCTION: Probably part of an ABC transporter complex. Probably
CC       responsible for the translocation of the substrate across the membrane
CC       (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins (MT0079),
CC       two transmembrane proteins (MT0078) and a solute-binding protein.
CC       {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the ABC-4 integral membrane protein family.
CC       {ECO:0000305}.
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DR   EMBL; AE000516; AAK44302.1; -; Genomic_DNA.
DR   PIR; A70849; A70849.
DR   RefSeq; WP_003400616.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WG16; -.
DR   SMR; P9WG16; -.
DR   EnsemblBacteria; AAK44302; AAK44302; MT0078.
DR   GeneID; 45424034; -.
DR   KEGG; mtc:MT0078; -.
DR   PATRIC; fig|83331.31.peg.83; -.
DR   HOGENOM; CLU_068246_0_0_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..349
FT                   /note="Uncharacterized ABC transporter permease MT0078"
FT                   /id="PRO_0000428440"
FT   TRANSMEM        16..36
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        231..251
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        284..304
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        307..327
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          111..139
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   349 AA;  36410 MW;  BE1F86496FDD8B32 CRC64;
     MLFAALRDMQ WRKRRLVITI ISTGLIFGMT LVLTGLANGF RVEARHTVDS MGVDVFVVRS
     GAAGPFLGSI PFPDVDLARV AAEPGVMAAA PLGSVGTIMK EGTSTRNVTV FGAPEHGPGM
     PRVSEGRSPS KPDEVAASST MGRHLGDTVE VGARRLRVVG IVPNSTALAK IPNVFLTTEG
     LQKLAYNGQP NITSIGIIGM PRQLPEGYQT FDRVGAVNDL VRPLKVAVNS ISIVAVLLWI
     VAVLIVGSVV YLSALERLRD FAVFKAIGTP TRSIMAGLAL QALVIALLAA VVGVVLAQVL
     APLFPMIVAV PVGAYLALPV AAIVIGLFAS VAGLKRVVTV DPAQAFGGP