ID   Y072_MYCTU              Reviewed;         349 AA.
AC   P9WG17; L0T2H8; O53617; Q7DAI3;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 39.
DE   RecName: Full=Uncharacterized ABC transporter permease Rv0072;
GN   OrderedLocusNames=Rv0072;
OS   Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=9634230; DOI=10.1038/31159;
RA   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA   Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA   Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA   Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA   Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA   Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA   Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA   Barrell B.G.;
RT   "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT   genome sequence.";
RL   Nature 393:537-544(1998).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=21969609; DOI=10.1074/mcp.m111.011627;
RA   Kelkar D.S., Kumar D., Kumar P., Balakrishnan L., Muthusamy B., Yadav A.K.,
RA   Shrivastava P., Marimuthu A., Anand S., Sundaram H., Kingsbury R.,
RA   Harsha H.C., Nair B., Prasad T.S., Chauhan D.S., Katoch K., Katoch V.M.,
RA   Kumar P., Chaerkady R., Ramachandran S., Dash D., Pandey A.;
RT   "Proteogenomic analysis of Mycobacterium tuberculosis by high resolution
RT   mass spectrometry.";
RL   Mol. Cell. Proteomics 10:M111.011627-M111.011627(2011).
CC   -!- FUNCTION: Probably part of an ABC transporter complex. Probably
CC       responsible for the translocation of the substrate across the membrane
CC       (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins (Rv0073),
CC       two transmembrane proteins (Rv0072) and a solute-binding protein.
CC       {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the ABC-4 integral membrane protein family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AL123456; CCP42795.1; -; Genomic_DNA.
DR   PIR; A70849; A70849.
DR   RefSeq; NP_214586.1; NC_000962.3.
DR   RefSeq; WP_003400616.1; NZ_NVQJ01000005.1.
DR   AlphaFoldDB; P9WG17; -.
DR   SMR; P9WG17; -.
DR   STRING; 83332.Rv0072; -.
DR   PaxDb; P9WG17; -.
DR   DNASU; 886984; -.
DR   GeneID; 45424034; -.
DR   GeneID; 886984; -.
DR   KEGG; mtu:Rv0072; -.
DR   TubercuList; Rv0072; -.
DR   eggNOG; COG0577; Bacteria.
DR   OMA; GDASYSH; -.
DR   PhylomeDB; P9WG17; -.
DR   Proteomes; UP000001584; Chromosome.
DR   GO; GO:0005576; C:extracellular region; HDA:MTBBASE.
DR   GO; GO:0005887; C:integral component of plasma membrane; HDA:MTBBASE.
DR   GO; GO:0005886; C:plasma membrane; HDA:MTBBASE.
PE   1: Evidence at protein level;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..349
FT                   /note="Uncharacterized ABC transporter permease Rv0072"
FT                   /id="PRO_0000395862"
FT   TRANSMEM        16..36
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        231..251
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        284..304
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        307..327
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          111..139
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   349 AA;  36410 MW;  BE1F86496FDD8B32 CRC64;
     MLFAALRDMQ WRKRRLVITI ISTGLIFGMT LVLTGLANGF RVEARHTVDS MGVDVFVVRS
     GAAGPFLGSI PFPDVDLARV AAEPGVMAAA PLGSVGTIMK EGTSTRNVTV FGAPEHGPGM
     PRVSEGRSPS KPDEVAASST MGRHLGDTVE VGARRLRVVG IVPNSTALAK IPNVFLTTEG
     LQKLAYNGQP NITSIGIIGM PRQLPEGYQT FDRVGAVNDL VRPLKVAVNS ISIVAVLLWI
     VAVLIVGSVV YLSALERLRD FAVFKAIGTP TRSIMAGLAL QALVIALLAA VVGVVLAQVL
     APLFPMIVAV PVGAYLALPV AAIVIGLFAS VAGLKRVVTV DPAQAFGGP