Y0777_DICDI
ID Y0777_DICDI Reviewed; 1823 AA.
AC Q54UW4;
DT 03-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT 24-MAY-2005, sequence version 1.
DT 25-MAY-2022, entry version 88.
DE RecName: Full=Bromodomain-containing protein DDB_G0280777;
GN ORFNames=DDB_G0280777;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
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DR EMBL; AAFI02000038; EAL67046.1; -; Genomic_DNA.
DR RefSeq; XP_641023.1; XM_635931.1.
DR AlphaFoldDB; Q54UW4; -.
DR SMR; Q54UW4; -.
DR STRING; 44689.DDB0220698; -.
DR PaxDb; Q54UW4; -.
DR PRIDE; Q54UW4; -.
DR EnsemblProtists; EAL67046; EAL67046; DDB_G0280777.
DR GeneID; 8622725; -.
DR KEGG; ddi:DDB_G0280777; -.
DR dictyBase; DDB_G0280777; -.
DR eggNOG; KOG1472; Eukaryota.
DR HOGENOM; CLU_237569_0_0_1; -.
DR InParanoid; Q54UW4; -.
DR PRO; PR:Q54UW4; -.
DR Proteomes; UP000002195; Chromosome 3.
DR GO; GO:0000124; C:SAGA complex; IBA:GO_Central.
DR GO; GO:0046695; C:SLIK (SAGA-like) complex; IBA:GO_Central.
DR GO; GO:0005198; F:structural molecule activity; IBA:GO_Central.
DR GO; GO:0016573; P:histone acetylation; IBA:GO_Central.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR Gene3D; 1.20.920.10; -; 1.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR037782; Spt7.
DR PANTHER; PTHR47343; PTHR47343; 2.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00297; BROMO; 1.
DR SUPFAM; SSF47370; SSF47370; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
PE 4: Predicted;
KW Bromodomain; Reference proteome.
FT CHAIN 1..1823
FT /note="Bromodomain-containing protein DDB_G0280777"
FT /id="PRO_0000365738"
FT DOMAIN 324..394
FT /note="Bromo"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00035"
FT REGION 44..83
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 200..281
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 429..654
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 753..781
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 855..886
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 949..993
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1055..1079
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1190..1386
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1453..1477
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1679..1823
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 44..63
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 200..214
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 221..250
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 251..265
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 429..556
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 568..596
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 597..617
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 963..993
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1194..1386
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1679..1714
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1715..1756
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1757..1777
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1791..1808
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1823 AA; 213172 MW; 35628BBBE73102C0 CRC64;
MDHITMEEKI NKKTKHIFSN NYDNILSDKQ VQCIYKEFFN NNKDNNNNKR FNENGNQINQ
IDFNSNKEEE KEEKEEKEKE EDEDNITILD DVYYSLEYDF EDYIKYSKIL TEKIEKERIT
QLFEQEKQNR LIRYHQRIQQ QKVIKEQLNV NMELLEKRKL LETELSLKSN QLNQCQTQLQ
QFQSTMTLLQ SQHQQTINKL KQTQSEQLQK RRNQQHQNLL KKQKIQKEKE EREQKEKEQK
EKEQKEKEEQ QQQLFLLQQQ QQQEEESKTT NKKKRNSRTT SINRVFRSLL TDVKVPAKKF
NGLKSEAQEE MYDQLDTVLN QLKDYSDHSF PFLTKVRPSE APNYYEIIKK PMDLSLMTKK
LKKLEYQSKF EFQLDLNLIF TNCRIYNTDP SGKVYVEHAN KMEKKSKDLM KNVKDLDFSM
DILKDIVDEN KNNNNSNNSV DNNNSLKKGR TSTPNKKQKT SNSTTTTTTT TTTTTATTPN
LLNTPLSSPP YTPCSPSTIS TVSSTPTTPQ SADCPLSPFQ QQQQQQTQAQ QQPTSNSPRN
TTTTTTTITS PISPRETNKD VIMEEEEESS SSSLSSSSLA LNSQNENGVN KSIEDSTGVK
MESEESTNVK KEENQSGDCE NQTTTTTTKE EGEEQQEQED EEQQQQQQQQ EEQTLEIENE
EDIINNFNSE IESLNNDFSE KTLQLSIQIK EISEKTEHFK INNSKIQQNL DELPLADKLN
LDINNAKELV DDNIELDDSE IIIPPYLNNN NNNCNNNNNN NDNNNNNNID NDNDNNNNNS
LENSFEIEKS KKINKFKELT KENRVRKLKY FLDQQSLPFN KREAFIRTPY FMNTFYNLDL
QQQNQKQQQI FNQEINDNDD DNNNNNNNNN NNNNNNNNNN NNNNKPKVMS AIQKMDQDFM
DLKVGFFPEL THLSNSIPII TPNYPITCKN SSIDNSVTTP SKSLLRLLNS SKSNNNSNNK
KEKQCNYNRE GEDDEGRGEE QKEKEEEKED EDFPNIITND IAYILLSKSI AKSIESESCL
HGTTQETMLI FTDIVSSFIG KIGKLFNKYY SNNGLPNNKS TTTQTTPTTQ LQPPPPPPSL
SLPPSLLLNS IVTDIFGDSL GILLLKDYMI KKSKNQQIYD DPLFELEVEF ENDHLQSDNI
LQNNNGDIDI NESMEIDILG EDDIIDIDDT GLFGHYPRYI EEPAEITLFI DPKPIQKPTT
NTTTNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNSNSN NNNNNNNSNS
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNSINNNN HNNNNNNNNN INNNNNNNNN
NNNNNNNNNN INNNNNNNIN NNNNNINNYN NNYNNNNNNN NNNNNNNNNN NNNNNNNNYP
KPIQASTQTG NLGIQQQLQQ QQLHQLQQQQ QLQQQYQIQQ QQLHLQQQQQ QQQQLKLQQI
QFQQMQQQQQ QQQLQQQTRQ PSQPQTPQMQ SQPQTPQILS QPQQQLQQLQ QQQLQQQQQL
QQQQLQQQQL FQQQQQQQQQ QQQQQQQQQQ QQQQQQQLLH PQQMQIQQNL QQPLQQIQQQ
QQIQQQQQQQ LQQQQQQQQQ QQQQQQQQQQ QQQQQQQQQQ HHQQLQQLQP QQQQQLQQLQ
PQQLQQLQQL QQLQQLQQLQ QLQPQQLQQL QQLQQLQPQQ LQQPQQLQPQ QLQQQQLQQQ
QQPQQQQQQP QQQPQQQPQQ QQQPQYQTTF QSIASPKEKD KEREKEKERE REKEKDRKFK
KVKKTESKKE SKKSLNDSSN SDINTSVEQH SPLSPQPISS SKPTPPPVSS KQPQTTQSNT
TTTQDSIPPI EQKKKRGRPQ KKQ
